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Journal ArticleDOI

Current knowledge of Schisandra chinensis (Turcz.) Baill. (Chinese magnolia vine) as a medicinal plant species: a review on the bioactive components, pharmacological properties, analytical and biotechnological studies

01 Apr 2017-Phytochemistry Reviews (Springer Netherlands)-Vol. 16, Iss: 2, pp 195-218
TL;DR: The article presents latest available information on the chemical composition of this plant species and gives a short resume of their beneficial effects in biological systems in vitro, in animals, and in humans, thus underlining their medicinal potential.
Abstract: Schisandra chinensis Turcz. (Baill.) is a plant species whose fruits have been well known in Far Eastern medicine for a long time. However, schisandra seems to be a plant still underestimated in contemporary therapy still in the countries of East Asia. The article presents latest available information on the chemical composition of this plant species. Special attention is given to dibenzo cyclooctadiene lignans. In addition, recent studies of the biological activity of dibenzocyclooctadiene lignans and schisandra fruit extracts are recapitulated. The paper gives a short resume of their beneficial effects in biological systems in vitro, in animals, and in humans, thus underlining their medicinal potential. The cosmetic properties are depicted, too. The analytical methods used for assaying schisandra lignans in the scientific studies and also in industry are also presented. Moreover, special attention is given to the information on the latest biotechnological studies of this plant species. The intention of this review is to contribute to a better understanding of the huge potential of the pharmacological relevance of S. chinensis.

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Citations
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Journal ArticleDOI
Zijian Li1, Xin He1, Fei Liu1, Jue Wang1, Juan Feng1 
TL;DR: This review summarizes the physicochemical properties and biological functions of polysaccharides from two Schisandra fruits, and the application prospects of these bioactive macromolecules in future daily life and medicine.

98 citations

01 Jan 1997
TL;DR: It is shown that in the scope of a particular but quite general functional class it is possible to automatically choose the best equation form to represent a physical process, avoiding the hard work of analytical model definition that the designer should do.
Abstract: In this paper we propose an original modeling method. Our work can be considered as somewhere between classical modeling methods and learning based methods. We show that in the scope of a particular but quite general functional class it is possible to automatically choose the best equation form to represent a physical process, avoiding the hard work of analytical model definition that the designer should do. Our method uses an experimental protocol where the parameters identification is limited to one entry dimension problems, reducing the amount of data required by the model acquisition. The models generated by our method can be easily differentiated, corrected and reused. The method can be particularly useful in robotics where the functional form the method hands can be easily found in many kinds of problems.

90 citations

Journal ArticleDOI
TL;DR: The experimental findings support the extracts and lignan components from S. chinensis can be used as new therapeutic agents to treat various neurodegenerative diseases and are highlighted as promising resources for the development of natural and effective agents for neuroprotective and cognitive enhancement effects.

86 citations

Journal ArticleDOI
TL;DR: Two types of antiviral lignan—podophyllotoxin and bicyclol, which are used to treat venereal warts and chronic hepatitis B in clinical, serve as examples of using lignans for antivirals—are discussed in some detail.
Abstract: Lignans are widely produced by various plant species; they are a class of natural products that share structural similarity. They usually contain a core scaffold that is formed by two or more phenylpropanoid units. Lignans possess diverse pharmacological properties, including their antiviral activities that have been reported in recent years. This review discusses the distribution of lignans in nature according to their structural classification, and it provides a comprehensive summary of their antiviral activities. Among them, two types of antiviral lignans-podophyllotoxin and bicyclol, which are used to treat venereal warts and chronic hepatitis B (CHB) in clinical, serve as examples of using lignans for antivirals-are discussed in some detail. Prospects of lignans in antiviral drug discovery are also discussed.

85 citations


Cites background from "Current knowledge of Schisandra chi..."

  • ...Schisandra Chinensis (Turcz.) Baill. is the most famous plant in Schisandraceae family, and the fruits (called Fructus Schizandrae) were widely used as a traditional Chinese medicine for treating hepatitis, myocardial disorders, and hyperlipidemia and neurodegenerative diseases in the countries of East Asia and others [70] [71] [72] ....

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Journal ArticleDOI
TL;DR: The present review focuses on the composition, pharmacology, and results of experimental trials of selected medicinal plants, finding that further research is needed to identify, characterize, and standardize the active ingredients, useful compounds, and their preparations for the treatment of liver diseases.
Abstract: Insight into the hepatoprotective effects of medicinally important plants is important, both for physicians and researchers. Main reasons for the use of herbal medicine include their lesser cost compared with conventional drugs, lesser undesirable drug reactions and thus high safety, and reduced side effects. The present review focuses on the composition, pharmacology, and results of experimental trials of selected medicinal plants: Silybum marianum (L.) Gaertn., Glycyrrhiza glabra, Phyllanthus amarus Schumach. & Thonn., Salvia miltiorrhiza Bunge., Astragalus membranaceus (Fisch.) Bunge, Capparis spinosa (L.), Cichorium intybus (L.), Solanum nigrum (L.), Sapindus mukorossi Gaertn., Ginkgo biloba (L.), Woodfordia fruticosa (L.) Kurz, Vitex trifolia (L.), Schisandra chinensis (Turcz.) Baill., Cuscuta chinensis (Lam.), Lycium barbarum, Angelica sinensis (Oliv.) Diels, and Litsea coreana (H. Lev.). The probable modes of action of these plants include immunomodulation, stimulation of hepatic DNA synthesis, simulation of superoxide dismutase and glutathione reductase to inhibit oxidation in hepatocytes, reduction of intracellular reactive oxygen species by enhancing levels of antioxidants, suppression of ethanol-induced lipid accumulation, inhibition of nucleic acid polymerases to downregulate viral mRNA transcription and translation, free radical scavenging and reduction of hepatic fibrosis by decreasing the levels of transforming growth factor beta-1, and collagen synthesis in hepatic cells. However, further research is needed to identify, characterize, and standardize the active ingredients, useful compounds, and their preparations for the treatment of liver diseases.

82 citations

References
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Journal ArticleDOI
TL;DR: In vivo redox biosensing resolves the spatiotemporal dynamics of compartmental responses to local ROS generation and provide a basis for understanding how compartment-specific redox dynamics may operate in retrograde signaling and stress 67 acclimation in plants.
Abstract: In experiments with tobacco tissue cultured on White's modified medium (basal meditmi hi Tnhles 1 and 2) supplemenk'd with kiticthi and hidoleacctic acid, a slrikin^' fourlo (ive-told intTease iu yield was ohtaitu-d within a three to Tour week j^rowth period on addition of an aqtteotis exlrarl of tobacco leaves (Fi^'ures 1 and 2). Subse(iueutly it was found Ihiit this jnoniotiou oi' f^rowih was due mainly though nol entirely to inorj^auic rather than organic con.stitttenls in the extract. In the isolation of Rrowth factors from plant tissues and other sources inorj '̂anic salts are fre(|uently carried along with fhe organic fraclioits. When tissue cultures are used for bioassays, therefore, il is necessary lo lake into account increases in growth which may result from nutrient elements or other known constituents of the medium which may he present in the te.st materials. To minimize interference trom rontaminaitis of this type, an altempt has heen made to de\\eh)p a nieditmi with such adequate supplies of all re(iuired tnineral nutrients and cotntnott orgattic cottslitueitls that no apprecial»le change in growth rate or yield will result from the inlroduclion of additional amounts in the range ordinarily expected to be present in tnaterials to be assayed. As a point of referetice for this work some of the culture media in mc)st common current use will he cotisidered briefly. For ease of comparis4)n Iheir mineral compositions are listed in Tables 1 and 2. White's nutrient .solution, designed originally for excised root cultures, was based on Uspeuski and Uspetiskaia's medium for algae and Trelease and Trelease's micronutrieni solution. This medium also was employed successfully in the original cttltivation of callus from the tobacco Iiybrid Nicotiana gtauca x A', tanijadorffii, atitl as further modified by White in 194̂ ^ and by others it has been used for the

63,098 citations

12 Nov 1980

2,777 citations


"Current knowledge of Schisandra chi..." refers methods in this paper

  • ...All of the cell lines were grown on Westvaco medium-WV5 (Lloyd and McCown 1980), with 2 % sucrose, 2 mM glutamine and plant growth regulators (PGRs): 6-benzylaminopurine (BA) and 2,4-dichlorophenoxyacetic acid (2,4-...

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  • ...Callus cultures were maintained on Murashige and Skoog (MS) (1962) and Woody Plant (WP) (Lloyd and McCown 1980) media in full and half strength (1/2 MS or 1/2 WP) salt formulations, additionally following PGRs were tested: 2,4-...

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Book
01 Jan 1986
TL;DR: The therapeutic use of herbs and herbal medicines in the world s great traditional medical systems is guided by the principles and precepts of that system, generally speaking the standardized applications of chinese herbs began since the publishing of shang han lun.
Abstract: kampo medicine the practice of chinese herbal itm, sargassum seaweed hai zao chinese herbs healing, chinese herbal supplements health benefit side effects, herbal therapeutics and materia medica greek medicine, chinese herbs healing art of herbal remedies revealed, herbal medicine materia medica alphabetic listing, herbal glossary traditional chinese medicine information, evidence based complementary and alternative medicine, consortium for globalization of chinese medicine, journal of herbal medicine elsevier, the lessons of shennong the basis of chinese herb medicine, traditional chinese medicine wikipedia, chinese medicine chronology shen nong com, kudzu benefits uses dosage and side effects, traditional chinese medicine in depth nccih, the benefits of traditional chinese medicine dr axe, traditional chinese medicine unable to stop animal time, amfi herbal medicine resource guide, gate of life acupuncture traditional chinese medicine, traditional chinese medicine study tour beijing theme tour, chinese medicine division cmd gov hk, five elements basics of traditional chinese medicine, tcm basics tcm traditional chinese medicine tcm101, materia medica wikipediaitm online provides education and offers theraputic programs with a focus on natural healing techniques such as herbal formulas acupuncture massage diet nutrition and general health care itm is a 501 c 3 tax exempt non profit organization the primary focus of its efforts is the training of health professionals so that they are better able to provide effective and safe natural, ryan drum december 12 2015 at 4 51 am the recent vilification of sargassum spp is unfortunate it is a tasty nutritious abundant seaweed which dries easily and can be stored for many months after harvest and drying in airtight containers, chinese herbal supplements treatment and therapy chinese herbs supplements and their medical therapeutic benefit a list and definition of several herbal products and information on their uses by ray sahelian m d april 4 2015, herbal therapeutics and materia medica the therapeutic use of herbs and herbal medicines in the world s great traditional medical systems is guided by the principles and precepts of that system, generally speaking the standardized applications of chinese herbs began since the publishing of shang han lun and jin gui yao lue the treatise on cold damage disorders and miscellaneous illnesses collated by zhang zhongjing who is deemed as the founding father of classic formulas, alphabetic listing of herbal medicine materia medica disclaimer the information provided on healthworld online is for educational purposes only and is not intended as a substitute for professional medical advice diagnosis or treatment always seek professional medical advice from your physician or other qualified healthcare provider with any questions you may have regarding a medical, 1 effects on reproductive organs animal studies a 30g kg day dose of radix morindae officinalis decoction was administered to castrated mice once a day for 15 days results showed that the weights of levator ani muscles seminal vesicle and prostate were not significantly effected 11 female rats administered with 20g kg radix morindae officinalis decoction twice a day by gavage for, many americans not completely satisfied with traditional western medicine have turned to alternative and complementary medicine which explains the increasing popularity of the herbal products and the chinese herbal medicine

906 citations


"Current knowledge of Schisandra chi..." refers background in this paper

  • ...It has its natural habitats in north-eastern China, Korea, Japan, in the eastern part of Russia, in Primorsk, on the Kuril Islands and in the south of the Sakhalin Island (Bensky and Gamble 1993)....

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  • ...The material is also known from the traditional Russian medicine, in which it was described as a tonic, reducing hunger, fatigue, delaying the aging process, increasing vitality, and improving mental health (Fil’kin 1952; Bensky and Gamble 1993)....

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Journal ArticleDOI
TL;DR: Schisandra chinensis (Turcz.) Bail is often referred to as an example of a medicinal plant with use in modern Chinese medicine and has been used as an adaptogen in the official medicine of the USSR in the early 1960s.

410 citations