scispace - formally typeset
Search or ask a question
Journal ArticleDOI

Current status and perspectives of zinc-based absorbable alloys for biomedical applications

TL;DR: This review provides the most recent progress in the development of absorbable Zn-based alloys for biomedical implant applications, primarily for cardiovascular and orthopedic devices and summarizes the research advances to date.
About: This article is published in Acta Biomaterialia.The article was published on 2019-10-01 and is currently open access. It has received 146 citations till now.
Citations
More filters
Journal ArticleDOI
TL;DR: Recent research and development on Zn-based BMs are reviewed in conjunction with discussion of their advantages and limitations in relation to existing BMs, and the underlying roles of alloy composition, microstructure, and processing technique on the mechanical and corrosion properties are discussed.

170 citations


Cites background from "Current status and perspectives of ..."

  • ...In fact, the exceptional grain refinement achieved in SPD-processed Zn-based materials simultaneously improves their mechanical properties and corrosion resistance [49]....

    [...]

Journal ArticleDOI
TL;DR: Reduced graphene oxide (RGO) was used as reinforcement in Zn scaffold fabricated via laser additive manufacturing and showed that the homogeneously dispersed RGO simultaneously enhanced the strength and ductility of ZN scaffold.

131 citations


Cites background from "Current status and perspectives of ..."

  • ...44 V), which potentially has a more suitable degradation rate in clinical requirement [10]....

    [...]

Journal ArticleDOI
TL;DR: A Zn-1Cu-0.1Ti alloy is developed with enhanced mechanical strength, corrosion wear property, biocompatibility, and antibacterial ability for biodegradable implant material applications.

95 citations

Journal ArticleDOI
TL;DR: In this article, the role of common antibacterial metallic elements in improving the antibacterial properties and corrosion resistance of Mg-based alloys, including sliver (Ag), Zinc (Zn), and copper (Cu).

68 citations

Journal ArticleDOI
TL;DR: In this paper, a review of the functionalization treatment of micro-arc oxidation (MAO) coatings on Mg alloys, including endowing MAO coatings with antibacterial properties, corrosion resistance, biocompatibility and bioactivity is presented.

64 citations

References
More filters
Journal ArticleDOI

5,415 citations


"Current status and perspectives of ..." refers background in this paper

  • ...Both Mg and Fe are essential trace elements in the human body, with recommended daily intakes (RDI) of 240-420 mg and 8-18 mg, respectively, for adults (gender and age specific) [5]....

    [...]

  • ...Note that based on the RDI values reported for mature adults, the biocompatibility of Zn (RDI: 8-20 mg/day) is not as good as that of Mg (RDI: 240-420 mg/day), but very similar to that of Fe (RDI: 8-18 mg/day) [5,31]....

    [...]

Journal ArticleDOI
31 Oct 2002-Nature
TL;DR: A thermomechanical treatment of Cu is described that results in a bimodal grain size distribution, with micrometre-sized grains embedded inside a matrix of nanocrystalline and ultrafine (<300 nm) grains, which impart high strength, as expected from an extrapolation of the Hall–Petch relationship.
Abstract: Nanocrystalline metals--with grain sizes of less than 100 nm--have strengths exceeding those of coarse-grained and even alloyed metals, and are thus expected to have many applications. For example, pure nanocrystalline Cu (refs 1-7) has a yield strength in excess of 400 MPa, which is six times higher than that of coarse-grained Cu. But nanocrystalline materials often exhibit low tensile ductility at room temperature, which limits their practical utility. The elongation to failure is typically less than a few per cent; the regime of uniform deformation is even smaller. Here we describe a thermomechanical treatment of Cu that results in a bimodal grain size distribution, with micrometre-sized grains embedded inside a matrix of nanocrystalline and ultrafine (<300 nm) grains. The matrix grains impart high strength, as expected from an extrapolation of the Hall-Petch relationship. Meanwhile, the inhomogeneous microstructure induces strain hardening mechanisms that stabilize the tensile deformation, leading to a high tensile ductility--65% elongation to failure, and 30% uniform elongation. We expect that these results will have implications in the development of tough nanostructured metals for forming operations and high-performance structural applications including microelectromechanical and biomedical systems.

2,531 citations

Journal ArticleDOI
TL;DR: High pressure torsion (HPT) is a well-known technique for metal forming as discussed by the authors, where samples are subjected to a compressive force and concurrent torsional straining.

2,499 citations


"Current status and perspectives of ..." refers background in this paper

  • ...Another SPD process, HPT, considered the most promising in terms of producing true bulk nanostructures [155], has been applied to synthesize Zn-Mg hybrids with an interesting hardness-plasticity relationship that could be attractive for absorbable applications [113,137]....

    [...]

Journal ArticleDOI
TL;DR: Parts of zinc biology of the immune system are explored and a biological basis for the altered host resistance to infections observed during zinc deficiency and supplementation is attempted.

1,488 citations


"Current status and perspectives of ..." refers background in this paper

  • ...Epidermal system Acrodermatitis enteropathica, alopecia, skin ulcers, delayed wound healing [36,41,42]...

    [...]

Journal ArticleDOI
TL;DR: The state-of-the-art of topological design and manufacturing processes of various types of porous metals, in particular for titanium alloys, biodegradable metals and shape memory alloys are reviewed.

1,393 citations