Current status and perspectives of zinc-based absorbable alloys for biomedical applications
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...In fact, the exceptional grain refinement achieved in SPD-processed Zn-based materials simultaneously improves their mechanical properties and corrosion resistance [49]....
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...44 V), which potentially has a more suitable degradation rate in clinical requirement [10]....
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...Both Mg and Fe are essential trace elements in the human body, with recommended daily intakes (RDI) of 240-420 mg and 8-18 mg, respectively, for adults (gender and age specific) [5]....
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...Note that based on the RDI values reported for mature adults, the biocompatibility of Zn (RDI: 8-20 mg/day) is not as good as that of Mg (RDI: 240-420 mg/day), but very similar to that of Fe (RDI: 8-18 mg/day) [5,31]....
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...Another SPD process, HPT, considered the most promising in terms of producing true bulk nanostructures [155], has been applied to synthesize Zn-Mg hybrids with an interesting hardness-plasticity relationship that could be attractive for absorbable applications [113,137]....
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...Epidermal system Acrodermatitis enteropathica, alopecia, skin ulcers, delayed wound healing [36,41,42]...
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