Cytokines and major depression.
Citations
1,361 citations
Cites methods from "Cytokines and major depression."
...Adapted from Schiepers, Wichers, and Maes (2005), Dantzer, O’Connor, Freund, Johnson, and Kelley (2008), and DellaGioia and Hannestad (2010)....
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982 citations
Cites methods from "Cytokines and major depression."
...Thus, we called this theory the monocyte-T-lymphocyte hypothesis of depression, the cytokine hypothesis of depression, and the inflammatory hypothesis of depression (Maes, 1993, 1995, 1999, 2002; Schiepers et al., 2005)....
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794 citations
Cites background or methods from "Cytokines and major depression."
...Since then there have been many consistent findings over the years of increased levels of proinflammatory cytokines in patients with depression, e.g. interleukin-1 (IL-1), IL-2, IL-6, IL-8, IL-12, interferon-γ (IFNγ and tumor necrosis factor-α (TNFα) (review: Schiepers et al. 2005)....
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...This hypothesis was termed the monocyte-T-lymphocyte or cytokine hypothesis of depression (Maes 1993, 1995, 1999; Maes et al. 1995b; Schiepers et al. 2005)....
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709 citations
Cites background from "Cytokines and major depression."
...tion may contribute to therapy based on both the (a) depressive effects that cytokines can produce, as well as (b) on much evidence that classical anti-depressants have anti-inflammatory effects [59, 63]....
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692 citations
References
4,346 citations
3,751 citations
3,146 citations
"Cytokines and major depression." refers background in this paper
...studied by Yirmiya (1996). The effects of the bacterial endotoxin LPS, which is a potent activator of the immune system, on affective and cognitive functions were investigated in healthy human volunteers....
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...The parasympathetic vagal nucleus, located in the brain stem, may downregulate immune function and cytokine production through ACh signalling by the vagus nerve (cranial nerve X; Tracey, 2002)....
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3,012 citations
2,090 citations
"Cytokines and major depression." refers background in this paper
...TNF-a blockers, such as etanercept (EnbrelR) and infliximab (RemicadeR) have been administered to patients suffering from RA and IBD, respectively (Rogler and Andus, 1998; Weinblatt et al., 1999)....
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