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Journal ArticleDOI

Deep learning

28 May 2015-Nature (Nature Research)-Vol. 521, Iss: 7553, pp 436-444
TL;DR: Deep learning is making major advances in solving problems that have resisted the best attempts of the artificial intelligence community for many years, and will have many more successes in the near future because it requires very little engineering by hand and can easily take advantage of increases in the amount of available computation and data.
Abstract: Deep learning allows computational models that are composed of multiple processing layers to learn representations of data with multiple levels of abstraction. These methods have dramatically improved the state-of-the-art in speech recognition, visual object recognition, object detection and many other domains such as drug discovery and genomics. Deep learning discovers intricate structure in large data sets by using the backpropagation algorithm to indicate how a machine should change its internal parameters that are used to compute the representation in each layer from the representation in the previous layer. Deep convolutional nets have brought about breakthroughs in processing images, video, speech and audio, whereas recurrent nets have shone light on sequential data such as text and speech.
Citations
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Journal ArticleDOI
TL;DR: It is proposed that principles and techniques from the field of machine learning can help psychology become a more predictive science and an increased focus on prediction, rather than explanation, can ultimately lead to greater understanding of behavior.
Abstract: Psychology has historically been concerned, first and foremost, with explaining the causal mechanisms that give rise to behavior. Randomized, tightly controlled experiments are enshrined as the gold standard of psychological research, and there are endless investigations of the various mediating and moderating variables that govern various behaviors. We argue that psychology’s near-total focus on explaining the causes of behavior has led much of the field to be populated by research programs that provide intricate theories of psychological mechanism but that have little (or unknown) ability to predict future behaviors with any appreciable accuracy. We propose that principles and techniques from the field of machine learning can help psychology become a more predictive science. We review some of the fundamental concepts and tools of machine learning and point out examples where these concepts have been used to conduct interesting and important psychological research that focuses on predictive research ques...

1,026 citations


Cites background from "Deep learning"

  • ...…it is true that the representations learned by many state-of-the-art machine learning approaches— most notably “deep” artificial neural networks (LeCun et al., 2015)—can be impenetrable to human comprehension (but see Zeiler & Fergus, 2014), this is a property of specific approaches or…...

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  • ...…virtually all other models—as is increasingly the case in many psychologyrelated domains such as computer vision and natural language processing (LeCun et al., 2015)—one may want to consider the possibility that simpler, more interpretable models are simply not adequate for explaining the…...

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Journal ArticleDOI
TL;DR: Deep learning has advanced rapidly since the early 2000s and now demonstrates state-of-the-art performance in various fields, including bioinformatics as discussed by the authors, which has been emphasized in both academia and industry.
Abstract: In the era of big data, transformation of biomedical big data into valuable knowledge has been one of the most important challenges in bioinformatics. Deep learning has advanced rapidly since the early 2000s and now demonstrates state-of-the-art performance in various fields. Accordingly, application of deep learning in bioinformatics to gain insight from data has been emphasized in both academia and industry. Here, we review deep learning in bioinformatics, presenting examples of current research. To provide a useful and comprehensive perspective, we categorize research both by the bioinformatics domain (i.e. omics, biomedical imaging, biomedical signal processing) and deep learning architecture (i.e. deep neural networks, convolutional neural networks, recurrent neural networks, emergent architectures) and present brief descriptions of each study. Additionally, we discuss theoretical and practical issues of deep learning in bioinformatics and suggest future research directions. We believe that this review will provide valuable insights and serve as a starting point for researchers to apply deep learning approaches in their bioinformatics studies.

1,010 citations

Journal ArticleDOI
TL;DR: The past decade has allowed the development of a multitude of digital tools, now they can be used to remediate the COVID-19 outbreak.
Abstract: The past decade has allowed the development of a multitude of digital tools. Now they can be used to remediate the COVID-19 outbreak.

995 citations

Journal ArticleDOI
TL;DR: This survey focuses on more generic object categories including, but not limited to, road, building, tree, vehicle, ship, airport, urban-area, and proposes two promising research directions, namely deep learning- based feature representation and weakly supervised learning-based geospatial object detection.
Abstract: Object detection in optical remote sensing images, being a fundamental but challenging problem in the field of aerial and satellite image analysis, plays an important role for a wide range of applications and is receiving significant attention in recent years. While enormous methods exist, a deep review of the literature concerning generic object detection is still lacking. This paper aims to provide a review of the recent progress in this field. Different from several previously published surveys that focus on a specific object class such as building and road, we concentrate on more generic object categories including, but are not limited to, road, building, tree, vehicle, ship, airport, urban-area. Covering about 270 publications we survey (1) template matching-based object detection methods, (2) knowledge-based object detection methods, (3) object-based image analysis (OBIA)-based object detection methods, (4) machine learning-based object detection methods, and (5) five publicly available datasets and three standard evaluation metrics. We also discuss the challenges of current studies and propose two promising research directions, namely deep learning-based feature representation and weakly supervised learning-based geospatial object detection. It is our hope that this survey will be beneficial for the researchers to have better understanding of this research field.

994 citations


Cites background from "Deep learning"

  • ...l., 2007), and land-use classification (Pacifici et al., 2009). Here, we briefly review the structure of neural networks. For more details and the latest advances, readers can refer to (Bishop, 1995; LeCun et al., 2015). Neural networks are made up of a large number of simple processing units called nodes or neurons. The main task of a neuron is to receive input from its neighbors, to compute an output and to send t...

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Proceedings Article
01 Nov 2017
TL;DR: A sensitivity analysis of one-layer CNNs is conducted to explore the effect of architecture components on model performance; the aim is to distinguish between important and comparatively inconsequential design decisions for sentence classification.
Abstract: Convolutional Neural Networks (CNNs) have recently achieved remarkably strong performance on the practically important task of sentence classification (Kim, 2014; Kalchbrenner et al., 2014; Johnson and Zhang, 2014; Zhang et al., 2016). However, these models require practitioners to specify an exact model architecture and set accompanying hyperparameters, including the filter region size, regularization parameters, and so on. It is currently unknown how sensitive model performance is to changes in these configurations for the task of sentence classification. We thus conduct a sensitivity analysis of one-layer CNNs to explore the effect of architecture components on model performance; our aim is to distinguish between important and comparatively inconsequential design decisions for sentence classification. We focus on one-layer CNNs (to the exclusion of more complex models) due to their comparative simplicity and strong empirical performance, which makes it a modern standard baseline method akin to Support Vector Machine (SVMs) and logistic regression. We derive practical advice from our extensive empirical results for those interested in getting the most out of CNNs for sentence classification in real world settings.

984 citations


Cites methods from "Deep learning"

  • ...Deep and neural learning methods are now well established in machine learning (LeCun et al., 2015; Bengio, 2009)....

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References
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Journal ArticleDOI
TL;DR: A novel, efficient, gradient based method called long short-term memory (LSTM) is introduced, which can learn to bridge minimal time lags in excess of 1000 discrete-time steps by enforcing constant error flow through constant error carousels within special units.
Abstract: Learning to store information over extended time intervals by recurrent backpropagation takes a very long time, mostly because of insufficient, decaying error backflow. We briefly review Hochreiter's (1991) analysis of this problem, then address it by introducing a novel, efficient, gradient based method called long short-term memory (LSTM). Truncating the gradient where this does not do harm, LSTM can learn to bridge minimal time lags in excess of 1000 discrete-time steps by enforcing constant error flow through constant error carousels within special units. Multiplicative gate units learn to open and close access to the constant error flow. LSTM is local in space and time; its computational complexity per time step and weight is O. 1. Our experiments with artificial data involve local, distributed, real-valued, and noisy pattern representations. In comparisons with real-time recurrent learning, back propagation through time, recurrent cascade correlation, Elman nets, and neural sequence chunking, LSTM leads to many more successful runs, and learns much faster. LSTM also solves complex, artificial long-time-lag tasks that have never been solved by previous recurrent network algorithms.

72,897 citations

Journal ArticleDOI
01 Jan 1998
TL;DR: In this article, a graph transformer network (GTN) is proposed for handwritten character recognition, which can be used to synthesize a complex decision surface that can classify high-dimensional patterns, such as handwritten characters.
Abstract: Multilayer neural networks trained with the back-propagation algorithm constitute the best example of a successful gradient based learning technique. Given an appropriate network architecture, gradient-based learning algorithms can be used to synthesize a complex decision surface that can classify high-dimensional patterns, such as handwritten characters, with minimal preprocessing. This paper reviews various methods applied to handwritten character recognition and compares them on a standard handwritten digit recognition task. Convolutional neural networks, which are specifically designed to deal with the variability of 2D shapes, are shown to outperform all other techniques. Real-life document recognition systems are composed of multiple modules including field extraction, segmentation recognition, and language modeling. A new learning paradigm, called graph transformer networks (GTN), allows such multimodule systems to be trained globally using gradient-based methods so as to minimize an overall performance measure. Two systems for online handwriting recognition are described. Experiments demonstrate the advantage of global training, and the flexibility of graph transformer networks. A graph transformer network for reading a bank cheque is also described. It uses convolutional neural network character recognizers combined with global training techniques to provide record accuracy on business and personal cheques. It is deployed commercially and reads several million cheques per day.

42,067 citations

Journal ArticleDOI
01 Jan 1988-Nature
TL;DR: Back-propagation repeatedly adjusts the weights of the connections in the network so as to minimize a measure of the difference between the actual output vector of the net and the desired output vector, which helps to represent important features of the task domain.
Abstract: We describe a new learning procedure, back-propagation, for networks of neurone-like units. The procedure repeatedly adjusts the weights of the connections in the network so as to minimize a measure of the difference between the actual output vector of the net and the desired output vector. As a result of the weight adjustments, internal ‘hidden’ units which are not part of the input or output come to represent important features of the task domain, and the regularities in the task are captured by the interactions of these units. The ability to create useful new features distinguishes back-propagation from earlier, simpler methods such as the perceptron-convergence procedure1.

23,814 citations

Journal ArticleDOI
26 Feb 2015-Nature
TL;DR: This work bridges the divide between high-dimensional sensory inputs and actions, resulting in the first artificial agent that is capable of learning to excel at a diverse array of challenging tasks.
Abstract: The theory of reinforcement learning provides a normative account, deeply rooted in psychological and neuroscientific perspectives on animal behaviour, of how agents may optimize their control of an environment. To use reinforcement learning successfully in situations approaching real-world complexity, however, agents are confronted with a difficult task: they must derive efficient representations of the environment from high-dimensional sensory inputs, and use these to generalize past experience to new situations. Remarkably, humans and other animals seem to solve this problem through a harmonious combination of reinforcement learning and hierarchical sensory processing systems, the former evidenced by a wealth of neural data revealing notable parallels between the phasic signals emitted by dopaminergic neurons and temporal difference reinforcement learning algorithms. While reinforcement learning agents have achieved some successes in a variety of domains, their applicability has previously been limited to domains in which useful features can be handcrafted, or to domains with fully observed, low-dimensional state spaces. Here we use recent advances in training deep neural networks to develop a novel artificial agent, termed a deep Q-network, that can learn successful policies directly from high-dimensional sensory inputs using end-to-end reinforcement learning. We tested this agent on the challenging domain of classic Atari 2600 games. We demonstrate that the deep Q-network agent, receiving only the pixels and the game score as inputs, was able to surpass the performance of all previous algorithms and achieve a level comparable to that of a professional human games tester across a set of 49 games, using the same algorithm, network architecture and hyperparameters. This work bridges the divide between high-dimensional sensory inputs and actions, resulting in the first artificial agent that is capable of learning to excel at a diverse array of challenging tasks.

23,074 citations

Journal ArticleDOI
28 Jul 2006-Science
TL;DR: In this article, an effective way of initializing the weights that allows deep autoencoder networks to learn low-dimensional codes that work much better than principal components analysis as a tool to reduce the dimensionality of data is described.
Abstract: High-dimensional data can be converted to low-dimensional codes by training a multilayer neural network with a small central layer to reconstruct high-dimensional input vectors. Gradient descent can be used for fine-tuning the weights in such "autoencoder" networks, but this works well only if the initial weights are close to a good solution. We describe an effective way of initializing the weights that allows deep autoencoder networks to learn low-dimensional codes that work much better than principal components analysis as a tool to reduce the dimensionality of data.

16,717 citations