Defining community acquired pneumonia severity on presentation to hospital: an international derivation and validation study
Citations
5,558 citations
Cites background or methods from "Defining community acquired pneumon..."
...Objective criteria to identify patients for ICU admission include the initial ATS definition of severe CAP [5] and its subsequent modification [6, 82] , the CURB criteria [39, 45] , and PSI severity class V (or IV and V) [42] ....
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...In a cohort of ∼3000 patients, the mortality with a CURB-65 score of 0 was only 1.2%, whereas 3-4 points were associated with 31% mortality [45] ....
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...The most recent modification of the BTS criteria includes 5 easily measurable factors [45] ....
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...Age, by itself, was not felt to be an appropriate factor for the ICU admission decision, but the remainder of the CURB-65 criteria [45] were retained as minor criteria (with the exception of hypotension requiring vasopressors as a major criterion)....
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...The 2 most interesting are the PSI [42] and the British Thoracic Society (BTS) criteria [39, 45] ....
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3,097 citations
1,708 citations
Cites methods from "Defining community acquired pneumon..."
...pneumonia, using patient demographic and clinical variables from the time of diagnosis to predict 30-day mortality (39, 40)....
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1,333 citations
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Cites background or methods or result from "Defining community acquired pneumon..."
...The CURB65 score was developed based on a study of over 1000 prospectively studied patients with CAP from three countries: the UK, New Zealand and the Netherlands.255 [Ib] The 6-point CURB65 score, one point for each of Confusion, Urea ....
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...CURB65 score The CURB65 score was developed based on a study of over 1000 prospectively studied patients with CAP from three countries: the UK, New Zealand and the Netherlands.(255) [Ib] The 6-point CURB65 score, one point for each of Confusion, Urea ....
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...298 [II] [Ib] In prospective studies reporting from the UK, 41–45% of patients hospitalised with CAP had CURB65 scores of 0–1, 25–28% had a CURB65 score of 2 and 29–34% had CURB65 scores of 3 or more.(255) 257 Other predictive models have been developed, including models to predict admission to intensive care as the primary outcome, or to predict a composite outcome comprising either mortality or need for intensive care....
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...The CRB65 score has been specifically studied in over 6000 patients representing a mix of patients seen both in the community and in hospitals.(255) 286 287 289 296–299 [Ib] [II] [Ib] [II] [Ib] [II] [Ib] [II] All studies reported findings similar to the derivation study and, in certain studies, the CRB65 score was reported to be of similar discriminatory value to the CURB65 score....
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References
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