Determinants of multidrug-resistant tuberculosis in patients who underwent first-line treatment in Addis Ababa: a case control study
Selamawit Hirpa,Girmay Medhin,Belaineh Girma,Muluken Melese,Alemayehu Mekonen,Pedro Suarez,Gobena Ameni +6 more
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TLDR
Patients who were not in strict DOTS programs and did not adhere to first- line TB treatment and patients who experienced side effects during first-line treatment and Category II retreatment were at significantly increased risk of developing MDR-TB.Abstract:
Background
Worldwide, there were 650,000 multidrug-resistant tuberculosis (MDR-TB) cases in 2010, and in 2008 the World Health Organization estimated that 150,000 deaths occurred annually due to MDR-TB. Ethiopia is 15th among the 27 MDR-TB high-burden countries. This study identifies factors associated with the occurrence of MDR-TB in patients who underwent first-line TB treatment in Addis Ababa City.read more
Citations
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Directly observed therapy for treating tuberculosis
Jimmy Volmink,Paul Garner +1 more
TL;DR: The results of randomized controlled trials conducted in low-, middle-, and high-income countries provide no assurance that directly observed therapy compared with self administration of treatment has any quantitatively important effect on cure or treatment completion in people receiving treatment for tuberculosis.
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Adherence interventions and outcomes of tuberculosis treatment: A systematic review and meta-analysis of trials and observational studies.
Narges Alipanah,Narges Alipanah,Leah G. Jarlsberg,Cecily Miller,Nguyen Nhat Linh,Dennis Falzon,Ernesto Jaramillo,Payam Nahid +7 more
TL;DR: TB treatment outcomes are improved with the use of adherence interventions, such as patient education and counseling, incentives and enablers, psychological interventions, reminders and tracers, and digital health technologies.
Journal ArticleDOI
Psychological and Educational Intervention to Improve Tuberculosis Treatment Adherence in Ethiopia Based on Health Belief Model: A Cluster Randomized Control Trial
Habteyes Hailu Tola,Davoud Shojaeizadeh,Azar Tol,Gholamreza Garmaroudi,Mir Saeed Yekaninejad,Abebaw Kebede,Luche Tadesse Ejeta,Desta Kassa,Eveline Klinkenberg +8 more
TL;DR: Psychological counseling and educational interventions, which were guided by HBM, significantly decreased treatment non-adherence level among intervention group in TB patients who are on regular treatment.
Journal ArticleDOI
Risk factors for multidrug resistant tuberculosis patients in Amhara National Regional State.
TL;DR: TB treatment failure, cavitation on chest X-ray, contact with MDR-TB patients and low socioeconomic status were important risk factors for development of MDR -TB.
Journal ArticleDOI
Multidrug resistant tuberculosis: prevalence and risk factors in districts of metema and west armachiho, Northwest Ethiopia
TL;DR: The overall prevalence of MDR-TB was 5.7 % among cases at five health centers and a history of previous treatment was found to be a risk factor for being infected by an M DR-TB strain.
References
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Journal ArticleDOI
Risk factors for multidrug resistant tuberculosis in Europe: a systematic review
TL;DR: Previous treatment was the strongest determinant of MDR-TB in Europe, and the risk of MDA in foreign born people needs to be re-evaluated, taking into account any previous treatment.
Journal ArticleDOI
Multidrug-resistant tuberculosis (MDR-TB): epidemiology, prevention and treatment
TL;DR: There should be a strong suspicion of drug resistance, including MDR-TB, in persons with a history of prior treatment or in treatment failure cases, and the diagnosis depends on confirming the drug susceptibility pattern of isolated organisms, which is often only possible in resource-rich settings.
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Multidrug-Resistant Tuberculosis: A Menace That Threatens To Destabilize Tuberculosis Control
Surendra K. Sharma,Alladi Mohan +1 more
TL;DR: With newer effective anti-TB drugs still a distant dream, innovative approaches such as DOTS-Plus are showing promise for the management of patients with MDR-TB under program conditions and appear to be a hope for future.
Journal Article
Defaulting from DOTS and its determinants in three districts of Arsi Zone in Ethiopia.
B Tekle,D H Mariam,A Ali +2 more
TL;DR: Major factors contributing to high rates of defaulting were found to be lack of family support, inadequate knowledge about treatment duration and medication side effects, which should be taken into consideration in control programmes to reduce defaulting.