Deuterium magnetic resonance: theory and application to lipid membranes.
01 Aug 1977-Quarterly Reviews of Biophysics (Cambridge University Press)-Vol. 10, Iss: 3, pp 353-418
TL;DR: Proton and carbon-13 nmr spectra of unsonicated lipid bilayers and biological membranes are generally dominated by strong proton-proton and proton–carbon dipolar interactions and are rather difficult to analyse.
Abstract: Proton and carbon-13 nmr spectra of unsonicated lipid bilayers and biological membranes are generally dominated by strong proton–proton and proton–carbon dipolar interactions. As a result the spectra contain a large number of overlapping resonances and are rather difficult to analyse. Nevertheless, important information on the structure and dynamic behaviour of lipid systems has been provided by these techniques (Wennerstrom & Lindblom, 1977).
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TL;DR: The motivation for this review arises from the conviction that, as a result of the mass of experimental data and observations collected in recent years, the study of the physical properties of membranes is now entering a new stage of development.
Abstract: The motivation for this review arises from the conviction that, as a result of the mass of experimental data and observations collected in recent years, the study of the physical properties of membranes is now entering a new stage of development. More and more, experiments are being designed to answer specific, detailed questions about membranes which will lead to a quantitative understanding of the way in which the physical properties of membranes are related to and influence their biological function.
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TL;DR: DHA's interaction with other membrane lipids, particularly cholesterol, may play a prominent role in modulating the local structure and function of cell membranes.
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Book•
01 Jan 1963
TL;DR: In this article, the effect of changing the precession frequency of the magnetic field has been studied using NMR to study rate properties. But the effect is limited to the case of double and double resonance.
Abstract: 1. Elements of Resonance.- 2 Basic Theory.- 3. Magnetic Dipolar Broadening of Rigid Lattices.- 4. Magnetic Interactions of Nuclei with Electrons.- 5. Spin-Lattice Relaxation and Motional Narrowing of Resonance Lines.- 6. Spin Temperature in Magnetism and in Magnetic Resonance.- 7. Double Resonance.- 8. Advanced Concepts in Pulsed Magnetic Resonance.- 9. Multiple Quantum Coherence.- 10. Electric Quadrupole Effects.- 11. Electron Spin Resonance.- 12. Summary.- Problems.- Appendixes.- A. A Theorem About Exponential Operators.- B. Some Further Expressions for the Susceptibility.- D. A Theorem from Perturbation Theory.- E. The High Temperature Approximation.- F. The Effects of Changing the Precession Frequency - Using NMR to Study Rate Phenomena.- G. Diffusion in an Inhomogeneous Magnetic Field.- H. The Equivalence of Three Quantum Mechanics Problems.- I. Powder Patterns.- J. Time-Dependent Hamiltonians.- K. Correction Terms in Average Hamiltonian Theory - The Magnus Expansion.- Selected Bibliography.- References.- Author Index.
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Book•
17 Sep 2011
TL;DR: This special topics volume represents a complete update on new theoretical aspects and applications of the spin-label method and includes an IBM-compatible diskette supplied by David Schneider and Jack Freed which contains fast, accurate, ready-to-use software for slow-motion simulations.
Abstract: We present this special topics volume on an area which has not received thorough coverage for over 12 years. Spin Labeling: Theory and Applications represents a complete update on new theoretical aspects and applications of the spin-label method. In the "line-shape theory" sections, we are especially pleased to include an IBM-compatible diskette supplied by David Schneider and Jack Freed which contains fast, accurate, ready-to-use software for slow-motion simulations. Barney Bales discusses inhomogeneous broadening phenomena in detail. Several developments in techniques and interpretation in saturation transfer spectroscopy have appeared since the publica tion of Spin Labeling II: Theory and Applications (L. J. Berliner, ed., Academic Press, 1979). We have included an up-to-date chapter on spin-label applications by M. A. Hemminga and P. A. de Jager. By incorporating 15N and deuterium into nitroxide spin labels, several unique advantages are derived in line-shape analysis. Albert Beth and Bruce Robinson have contributed a detailed chapter on the analysis of these labels in the slow-motion regime while Jane Park and Wolfgang Trommer present the advantages for specific biochemical examples in our "applications" section. Derek Marsh's contri bution on spin-label spectral analysis may be regarded as a summary chapter which touches on several of the detailed spectral analysis methods described in the earlier chapters."
1,187 citations