Development of a next-generation antimicrobial wound dressing.
Citations
27 citations
27 citations
Additional excerpts
...This combination was effective against biofilm and reduced the signs of clinical infection in a 42-patient study.(37) Research into the cosmetic use of biosurfactants is developing due to their cleansing, emulsifying, foaming and skin hydrating properties....
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16 citations
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References
3,578 citations
"Development of a next-generation an..." refers background in this paper
...At this stage the bioi lm will be microscopic but may start to illicit an inl ammatory host response, and if unchecked, can develop into larger, more elaborate communities (16)....
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3,321 citations
"Development of a next-generation an..." refers background in this paper
...Established wound bioi lm therefore presents a serious infection risk, and may also seed bioi lm formation elsewhere in the wound (19)....
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1,203 citations
"Development of a next-generation an..." refers background in this paper
...Knowing that the complex three-dimensional matrix of EPS was generally comprised of hydrated polysaccharides, protein and DNA of microbial origin, as well as host-derived devitalised tissues (12,35), the search for safe and ef ective means by which to target this matrix was undertaken....
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896 citations
"Development of a next-generation an..." refers background in this paper
...As a result, bioi lm microorganisms can display tolerance towards systemic antibiotics and topically-applied antiseptics, such as silver or iodine (14), as well as host defence mechanisms, such as phagocytosis and enzyme-mediated microbial killing by neutrophils (15)....
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786 citations
"Development of a next-generation an..." refers background in this paper
...As a result, bioi lm microorganisms can display tolerance towards systemic antibiotics and topically-applied antiseptics, such as silver or iodine (14), as well as host defence mechanisms, such as phagocytosis and enzyme-mediated microbial killing by neutrophils (15)....
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