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Journal ArticleDOI

Developmental differences in hippocampal and cortical contributions to episodic retrieval.

01 Jun 2013-Cortex (Elsevier)-Vol. 49, Iss: 6, pp 1482-1493
TL;DR: The view that the development of episodic memory is supported by functional changes in the hippocampus as well as in other critical cortical regions is supported.
About: This article is published in Cortex.The article was published on 2013-06-01. It has received 126 citations till now. The article focuses on the topics: Semantic memory & Episodic memory.
Citations
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Journal ArticleDOI
TL;DR: The hypothesis that adolescent binge drinking leads to long-lasting changes in the adult brain that increase risks of adult psychopathology, particularly for alcohol dependence, is supported.
Abstract: Adolescence is a developmental period when physical and cognitive abilities are optimized, when social skills are consolidated, and when sexuality, adolescent behaviors, and frontal cortical functions mature to adult levels. Adolescents also have unique responses to alcohol compared with adults, being less sensitive to ethanol sedative–motor responses that most likely contribute to binge drinking and blackouts. Population studies find that an early age of drinking onset correlates with increased lifetime risks for the development of alcohol dependence, violence, and injuries. Brain synapses, myelination, and neural circuits mature in adolescence to adult levels in parallel with increased reflection on the consequence of actions and reduced impulsivity and thrill seeking. Alcohol binge drinking could alter human development, but variations in genetics, peer groups, family structure, early life experiences, and the emergence of psychopathology in humans confound studies. As adolescence is common to mammalian species, preclinical models of binge drinking provide insight into the direct impact of alcohol on adolescent development. This review relates human findings to basic science studies, particularly the preclinical studies of the Neurobiology of Adolescent Drinking in Adulthood (NADIA) Consortium. These studies focus on persistent adult changes in neurobiology and behavior following adolescent intermittent ethanol (AIE), a model of underage drinking. NADIA studies and others find that AIE results in the following: increases in adult alcohol drinking, disinhibition, and social anxiety; altered adult synapses, cognition, and sleep; reduced adult neurogenesis, cholinergic, and serotonergic neurons; and increased neuroimmune gene expression and epigenetic modifiers of gene expression. Many of these effects are specific to adolescents and not found in parallel adult studies. AIE can cause a persistence of adolescent-like synaptic physiology, behavior, and sensitivity to alcohol into adulthood. Together, these findings support the hypothesis that adolescent binge drinking leads to long-lasting changes in the adult brain that increase risks of adult psychopathology, particularly for alcohol dependence.

226 citations


Cites background or result from "Developmental differences in hippoc..."

  • ...The developmental trajectory of brain regional volumes in humans has been studied (Giedd et al., 1996; Sowell et al., 1999; Gogtay et al., 2006; Demaster and Ghetti, 2013) and is generally similar to that found in rats (Calabrese et al., 2013; Oguz, et al., 2013)....

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  • ...…the hippocampus and amygdala, mature during adolescence in humans (Giedd, et al., 1996; Sowell et al., 1999; Suzuki et al., 2005; Gogtay et al., 2006; Uematsu et al., 2012; Demaster and Ghetti, 2013) at a relatively faster pace than the prefrontal cortex (PFC) (see Casey et al., 2005 for review)....

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Journal ArticleDOI
TL;DR: It is argued that hippocampus-mediated binding continues to develop during middle childhood along with other cortical regions in the prefrontal and parietal cortex and the role of hippocampal projections to and from cortical regions is underscore.

220 citations

Journal ArticleDOI
TL;DR: Rostral prefrontal cortex (RPFC) supports self-generated, abstract thought processing in adolescence and becomes more specific to relational integration during development, which has implication for education.

159 citations


Cites background from "Developmental differences in hippoc..."

  • ...…et al., 2011), however he available data is limited as some studies only included articipants of one gender (e.g. Dumontheil et al., 2010b, 010c), and others did not test for potential gender differnces (e.g. DeMaster and Ghetti, 2013; Crone et al., 2009), ikely because of sample size limitations....

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  • ...…al., 2011). owever, some studies still show continuing improveents in episodic memory performance between late hildhood and adulthood (DeMaster and Ghetti, 2013; orsbach and Reimer, 2005), in particular in tasks requiring emory for combined features (e.g. objects and locations) Lorsbach and…...

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  • ...DeMaster and Ghetti (2013) scanned children aged 8–11-year old and adults aged 18–25-year old who were asked whether a drawing shown on the screen had been presented before or not (item memory) and what colour was the border of the drawing during its first presentation (context or source memory)....

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  • ...Overall, younger children perform orse than adolescents on source discrimination tasks, nd adolescents perform themselves worse than adults (De hastelaine et al., 2007; DeMaster and Ghetti, 2013; Ghetti t al., 2010)....

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Journal ArticleDOI
TL;DR: Examination of age-related differences in volumes of the hippocampal head, body, and tail and collected episodic memory measures in children ages 8-11 years and young adults suggests that protracted development of hippocampal subregions contribute to age- related differences in episodi memory.
Abstract: The hippocampus is critically involved in episodic memory, yet relatively little is known about how the development of this structure contributes to the development of episodic memory during middle to late childhood. Previous research has inconsistently reported associations between hippocampal volume and episodic memory performance during this period. We argue that this inconsistency may be due to assessing the hippocampus as a whole, and propose to examine associations separately for subregions along the longitudinal axis of the hippocampus. In the present study, we examined age-related differences in volumes of the hippocampal head, body, and tail, and collected episodic memory measures in children ages 8-11 years and young adults (N = 62). We found that adults had a smaller right hippocampal head, larger hippocampal body bilaterally, and smaller right hippocampal tail compared with children. In adults, but not in children, better episodic memory performance was associated with smaller right hippocampal head and larger hippocampal body. In children, but not in adults, better episodic memory was associated with larger left hippocampal tail. Overall, the results suggest that protracted development of hippocampal subregions contribute to age-related differences in episodic memory.

148 citations


Cites background or methods or result from "Developmental differences in hippoc..."

  • ...the present sample (DeMaster and Ghetti 2012), we investigated developmental differences in the recruitment of hippocampus and cortical regions during one of the episodic...

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  • ...2008) and based on research with fMRI showing the most sizeable differences from adults in the functional profile in the hippocampus (DeMaster and Ghetti 2012; Ghetti et al. 2010; Paz-Alonso et al. 2008; for evidence of developmental differences in hippocampal activation profile, see also Maril et al. 2010)....

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  • ...We had proposed the prediction that the hippocampal tail may be involved in episodic retrieval in children based on our recent results showing that children recruited the hippocampal tail bilaterally, but not the rest of the hippocampus, to retrieve episodic detail (DeMaster and Ghetti 2012); thus, it is possible that this region is the first during development to capture associations with episodic memory....

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Journal ArticleDOI
TL;DR: Age-related differences in hippocampal subfields and correlations between subfield volumes and episodic memory are examined and subfield development appears to follow a protracted developmental trajectory, and likely plays a pivotal role in episodicMemory development.

107 citations


Cites background from "Developmental differences in hippoc..."

  • ...…research; performance on these tasks has been shown to relate to typically developing hippocampal structure (DeMaster et al., 2013) and function (DeMaster and Ghetti, 2012; Ghetti et al., 2010a), and has been found to be sensitive to subtle purported hippocampal damage (Ghetti et al., 2010b)....

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References
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Journal ArticleDOI
TL;DR: The concept of false memories is not new; psychologists have been studying false memories in several laboratory paradigms for years as discussed by the authors and Schacter (in press) provides an historical overview of the study of memory distortions.
Abstract: False memories—either remembering events that never happened, or remembering them quite differently from the way they happened—have recently captured the attention of both psychologists and the public at large. The primary impetus for this recent surge of interest is the increase in the number of cases in which memories of previously unrecognized abuse are reported during the course of therapy. Some researchers have argued that certain therapeutic practices can cause the creation of false memories, and therefore, the apparent "recovery" of memories during the course of therapy may actually represent the creation of memories (Lindsay & Read, 1994; Loftus, 1993). Although the concept of false memories is currently enjoying an increase in publicity, it is not new; psychologists have been studying false memories in several laboratory paradigms for years. Schacter (in press) provides an historical overview of the study of memory distortions. Bartlett (1932) is usually credited with conducting the first experimental investigation of false memories; he had subjects read an Indian folktale, "The War of the Ghosts," and recall it repeatedly. Although he reported no aggregate data, but only sample protocols, his results seemed to show distortions in subjects' memories over repeated attempts to recall the story. Interestingly, Bartlett's repeated reproduction results never have been successfully replicated by later researchers (see Gauld & Stephenson, 1967; Roediger, Wheeler, & Rajaram, 1993); indeed, Wheeler and Roediger (1992) showed that recall of prose passages (including "The War of the Ghosts")

3,277 citations

Journal ArticleDOI
TL;DR: A conceptual framework for understanding adolescence is provided, which emphasizes how the very nature of this developmental transition requires an interdisciplinary approach—one that focuses on brain/behavior/social‐context interactions during this important maturational period.
Abstract: This article introduces and summarizes the goals of the symposium. It also provides an overview of a conceptual framework for understanding adolescence, which emphasizes how the very nature of this developmental transition requires an interdisciplinary approach-one that focuses on brain/behavior/social-context interactions during this important maturational period. More specifically it describes a set of neurobehavioral changes that appear to be linked to pubertal development, which appear to have a significant effect on motivation and emotion, and considers these puberty-specific changes in affect in relation to a much larger set of developmental changes in adolescence. This framework is used to argue for the need for a transdisciplinary dialogue that brings together work in several areas of neuroscience (including animal models) and normal development with clinical and social policy research aimed at early intervention and prevention strategies.

1,527 citations


"Developmental differences in hippoc..." refers background in this paper

  • ...Models of brain development underscore the importance of neurobiological changes occurring in adolescence (e.g., Casey et al., 2010; Crone, 2009; Dahl, 2004); recent studies document associations between levels of circulating sex hormones and hippocampal volumes during adolescence (Bramen et al.,…...

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Journal ArticleDOI
TL;DR: This article surveys the fMRI literature on PPC activation during remembering, a literature that complements earlier electroencephalography data and proposes three hypotheses concerning how parietal cortex might contribute to memory.

1,484 citations


"Developmental differences in hippoc..." refers background in this paper

  • ...…a supportive role to recollection and familiarity processes (Vilberg and Rugg, 2008; see also Shimamura, 2011 for a focus on relational binding in service of recollection), and accounts proposing the PPC as a temporary buffer in the service of assessment of mnemonic evidence (Wagner et al., 2005)....

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Journal ArticleDOI
TL;DR: Differences observed in developmental timing suggest a pattern of maturation in which areas with fronto-temporal connections develop more slowly than other regions, which is consistent with previous postmortem and imaging studies.

1,293 citations


"Developmental differences in hippoc..." refers background in this paper

  • ...…is now initial evidence that white matter tracts connecting the hippocampus with PFC and PPC increase their integrity during childhood and beyond (Lebel et al., 2008), and higher integrity in these tracts has been found to be associated with increased memory performance (Mabbott et al., 2009;…...

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Journal ArticleDOI
TL;DR: In primates, the posterior hippocampus (corresponding to the dorsal hippocampus of rodents) appears to be more important than anterior areas for encoding of spatial memory and certain forms of nonspatial memory.
Abstract: The hippocampus is critically involved in certain kinds of memory. During memory formation, it may operate as an integrated unit, or isolated parts may be responsible for different functions. Recent evidence suggests that the hippocampus is functionally differentiated along its dorsoventral (septotemporal) axis. The cortical and subcortical connections of the dorsal and ventral hippocampus are different, with information derived from the sensory cortices entering mainly in the dorsal two-thirds or three-quarters of the dentate gyrus. Rats can acquire a spatial navigation task if small tissue blocks are spared within this region, but equally large blocks at the ventral end are not capable of supporting spatial learning. In primates, the posterior hippocampus (corresponding to the dorsal hippocampus of rodents) appears to be more important than anterior areas for encoding of spatial memory and certain forms of nonspatial memory. The ventral (or anterior) hippocampal formation is to some extent disconnected from the rest of the structure both in terms of intrahippocampal and extrahippocampal connections and may be performing functions that are qualitatively different from, and independent of, those of the dorsal hippocampal formation.

1,238 citations


"Developmental differences in hippoc..." refers background in this paper

  • ...Though debate on this differentiation is still ongoing (Chua et al., 2007; Greicius et al., 2003; Moser and Moser, 1998; Schacter and Wagner, 1999), recent fMRI work by Giovanello et al. (2009) provided evidence that anterior and posterior regions may be critical for distinct retrieval processes....

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