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Developments and Applications of Calcium Phosphate Bone Cements

Changsheng Liu, +1 more
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TLDR
In this chapter, a further understanding of the chemical, physical, and biological properties of CPC, along with the clinical applications, is addressed to provide a deeper insight into the regulation mechanism between the material properties and the clinical uses.
Abstract
Calcium phosphate cement (CPC) has opened up a new era in the construction of bone-related defects in biomedical fields. Such unique properties as the easy shaping, injectability in practical use, excellent biocompatibility, and biodegradability of CPC make it a perfect substitution material and maintain the research focus during the years. In this chapter, the brief history, classification, setting mechanism, and kinetics of CPC are introduced. A further understanding of the chemical, physical, and biological properties of CPC, along with the clinical applications, is also addressed to provide a deeper insight into the regulation mechanism between the material properties and the clinical uses.

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A Comparative Review of Natural and Synthetic Biopolymer Composite Scaffolds.

TL;DR: An overview of various natural and synthetic polymers and their possible composite scaffolds with their physicochemical properties including biocompatibility, biodegradability, morphology, mechanical strength, pore size, and porosity are discussed in this article.
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Colloidal nanocrystal synthesis and the organic-inorganic interface

TL;DR: In this paper, the authors review what is known about nanocrystal growth and outline strategies for controlling it, and present a review of the current state-of-the-art in this area.
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Chemical insights into bioinks for 3D printing.

TL;DR: This review focuses on the nature of bioink components of natural or synthetic origin, and highlights the chemistry required for the establishment of the 3D network in conditions compatible with the selected 3D printing technique and cell survival.

Next Generation Calcium Phosphate-based Biomaterials

TL;DR: An in depth analysis of several key areas of calcium phosphate cement properties is presented with the aim of developing strategies that could lead to break-through improvements in the functional efficacies of these materials.
Journal ArticleDOI

Scaffolds and coatings for bone regeneration.

TL;DR: Despite the interesting advances which include the development of hybrid scaffolds, there are still important challenges that need to be addressed in order to fasten translation of scaffolds into the clinical scenario.
References
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TL;DR: A new technique for assaying infectivity of adenovirus 5 DNA has been developed and a reproducible relationship between amounts of DNA inoculated per culture and numbers of plaques produced was demonstrated.
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Toxic Potential of Materials at the Nanolevel

TL;DR: The establishment of principles and test procedures to ensure safe manufacture and use of nanomaterials in the marketplace is urgently required and achievable.
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Nanotoxicology: An Emerging Discipline Evolving from Studies of Ultrafine Particles

TL;DR: Results of older bio-kinetic studies with NSPs and newer epidemiologic and toxicologic studies with airborne ultrafine particles can be viewed as the basis for the expanding field of nanotoxicology, which can be defined as safety evaluation of engineered nanostructures and nanodevices.
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Cancer nanotechnology: opportunities and challenges.

TL;DR: Nanotechnology is a multidisciplinary field, which covers a vast and diverse array of devices derived from engineering, biology, physics and chemistry that can provide essential breakthroughs in the fight against cancer.
Journal ArticleDOI

Drug Delivery Systems: Entering the Mainstream

TL;DR: There is considerable interest in exploiting the advantages of DDS for in vivo delivery of new drugs derived from proteomics or genomics research and for their use in ligand-targeted therapeutics.