Diagnostic performance of 64-multidetector row coronary computed tomographic angiography for evaluation of coronary artery stenosis in individuals without known coronary artery disease: results from the prospective multicenter ACCURACY (Assessment by Coronary Computed Tomographic Angiography of Individuals Undergoing Invasive Coronary Angiography) trial.
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Cites background from "Diagnostic performance of 64-multid..."
...In patients with suspected CAD, multicentre studies using 64-slice CT have demonstrated sensitivities of 95–99% and specificities of 64–83% (Table 12) as well as negative predictive values of 97–99% for the identification of individuals with at least one coronary artery stenosis by ICA.103,105 Meta-analyses of smaller trials confirm a high sensitivity (98–99...
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...In patients with suspected CAD, multicentre studies using 64-slice CT have demonstrated sensitivities of 95–99% and specificities of 64–83% (Table 12) as well as negative predictive values of 97–99% for the identification of individuals with at least one coronary artery stenosis by ICA.(103,105) Meta-analyses of smaller trials confirm a high sensitivity (98–99%) and negative predictive value (99–100%), paired with lower specificity (82–89%) and positive predictive value (91–93%)....
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3,879 citations
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Cites background from "Diagnostic performance of 64-multid..."
...However, significant false positive rates underscore a general overestimation of CAD severity by CCTA, and even among obstructive CAD lesions identified by CCTA that are confirmed at ICA, only a minority of such lesions are causal of ischemia (8,10,11)....
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References
3,259 citations
"Diagnostic performance of 64-multid..." refers methods in this paper
...oronary artery classification, as previously described (3)....
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...The aim of the present prospective blinded multicenter tudy was to test the ability of current-generation 64ultidetector row CCTA to detect or exclude significant oronary artery stenosis in chest pain subjects without nown CAD, using an American Heart Association (AHA) lassification of coronary artery segments (3)....
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1,348 citations
"Diagnostic performance of 64-multid..." refers background in this paper
..., stress echocariogram, stress nuclear), whereas the diagnostic sensitivity nd NPV are higher (7)....
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