Discussion on bone healing rate and expression of cytokines and growth factors in rat models with simple fracture and brain injury
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It was found that the rate of bone healing in the combined group was faster than that in the fracture group, and the bone callus volume, trabecular width, and trABecular proportion of the rats in the Combined group were significantly higher than those in the fractures.About:
This article is published in Journal of King Saud University - Science.The article was published on 2020-06-01 and is currently open access. It has received 2 citations till now. The article focuses on the topics: Bone healing & Bone morphogenetic protein 7.read more
Citations
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Effects of exogenous nerve growth factor on the expression of BMP-9 and VEGF in the healing of rabbit mandible fracture with local nerve injury.
TL;DR: Sen Yang a liated stomatological hospital of zunyi medical university Jiao Cheng ( cjjuse2020@163.com ) a liations stom atologicalhospital of z uni medical university.
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Review of immunological plasma markers for longitudinal analysis of inflammation and infection in rat models
TL;DR: The blood markers that are most consistent with other outcome measures of the immune response in the rat are discussed, by reviewing their utility for longitudinal tracking of infection and/or inflammation in the following types of models: localized inflammation/arthritis, injury, infection, and injury + infection.
References
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Journal ArticleDOI
Osteoimmunology in Bone Fracture Healing.
Takehito Ono,Hiroshi Takayanagi +1 more
TL;DR: Accumulating evidence has begun to reveal the deeper picture of bone fracture healing, and Macrophages and interleukin (IL)-17-producing γδ T cells enhance bone healing, whereas CD8+ T cells impair bone repair.
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Relationship between heterotopic ossification and traumatic brain injury: Why severe traumatic brain injury increases the risk of heterotopic ossification.
TL;DR: A better understanding of the probable causes of traumatic brain injury–induced HO can provide new perspectives and ideas in preventing HO and may support to design more targeted therapies to reduce HO or enhance the bone formation.
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BMP9 a possible alternative drug for the recently withdrawn BMP7? New perspectives for (re-)implementation by personalized medicine
Vrinda Sreekumar,Romina H. Aspera-Werz,Gauri Tendulkar,Marie K. Reumann,Thomas Freude,Katja Breitkopf-Heinlein,Steven Dooley,Stefan Pscherer,Björn Gunnar Ochs,Ingo Flesch,Valeska Hofmann,Andreas K. Nussler,Sabrina Ehnert +12 more
TL;DR: Based on patient’s respective expression profiles, clinical application of rhBMP9 either solely or in combination withrhBMP2 and/or rhB MP7 can become a promising new approach to fit the patient's needs to promote fracture healing.
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Serum EGF and NGF levels of patients with brain injury and limb fracture
Yan-Feng Zhuang,Jie Li +1 more
TL;DR: The serum of NGF, EGF levels significantly increased when limb fracture combined with brain injury, so EGF and NGF may be involved in the process of fracture healing.
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Does the administration of melatonin during post-traumatic brain injury affect cytokine levels?
Fatemeh Dehghan,Nader Shahrokhi,Mohammad Khaksari,Zahra Soltani,Gholamreza Asadikorom,Ali Najafi,Nava Shahrokhi +6 more
TL;DR: Results showed that melatonin administration affected the brain levels of pro-inflammatory and anti-inflammatory cytokines involving in brain edema led to neuronal protection after TBI.