Disrupted amygdala-prefrontal functional connectivity in civilian women with posttraumatic stress disorder
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Cites background from "Disrupted amygdala-prefrontal funct..."
...Salience network and PTSD In addition to CEN abnormalities in PTSD, a number of studies have demonstrated connectivity alterations among brain areas related to the SN, such as between the anterior insula and other SN regions, including the amygdala (Birn, Patriat, Phillips, Germain, & Herringa, 2014; Cisler et al., 2013, 2014; Fonzo et al., 2010; Peterson, Thome, Frewen, & Lanius, 2014; Rabinak et al., 2011; Shang et al., 2014; Simmons, Norman, Spadoni, & Strigo, 2013; Simmons et al., 2008, 2011; Sripada, King, Garfinkel, et al., 2012; Sripada, King, Welsh, et al., 2012; Stevens et al., 2013; Tursich, Ros, Frewen, Calhoun, & Lanius, 2015)....
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...…Thome, Frewen, & Lanius, 2014; Rabinak et al., 2011; Shang et al., 2014; Simmons, Norman, Spadoni, & Strigo, 2013; Simmons et al., 2008, 2011; Sripada, King, Garfinkel, et al., 2012; Sripada, King, Welsh, et al., 2012; Stevens et al., 2013; Tursich, Ros, Frewen, Calhoun, & Lanius, 2015)....
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175 citations
Cites background from "Disrupted amygdala-prefrontal funct..."
...…Etkin and Wager, 2007; Lanius et al., 2010, 2015; Mickleborough et al., 2011; Patel et al., 2012; Pitman et al., 2012; Shin and Liberzon, 2010; Stevens et al., 2013; Weston, 2014; Yehuda et al., 2015; but also see the dissociative subtype of PTSD Lanius et al., 2010, 2015; Nicholson et al,…...
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...…by patients with posttraumatic stress disorder (PTSD) [Aghajani et al., 2016; Birn et al., 2014; Etkin and Wager, 2007; Lanius et al. 2010, 2015; Mickleborough et al., 2011; Patel et al., 2012; Pitman et al., 2012; Shin and Liberzon, 2010; Stevens et al., 2013; Weston, 2014; Yehuda et al., 2015]....
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...…and monitoring physiological condition with respect to emotion [Birn et al., 2014; Bruce et al., 2013; Craig, 2009; Etkin et al., 2011, 2015; Gasquoine, 2014; Kurth et al., 2010; Patel et al., 2012, 2015; Pitman et al., 2012; Sadeh et al., 2014; Stevens et al., 2013; Yehuda et al., 2015]....
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...…2010; Nicholson et al., 2016a; Rabinak et al., 2011; Sripada et al., 2012] and PFC [Birn et al., 2014; Brown et al., 2014; Nicholson et al., 2015; Stevens et al., 2013] among patients with PTSD. Notably, heightened symptoms of hyperarousal in PTSD are correlated with negative medial PFC-amygdala…...
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163 citations
References
17,213 citations
"Disrupted amygdala-prefrontal funct..." refers background in this paper
...Among the general population, PTSD is estimated to affect approximately 7% (Kessler et al., 2005), and a critical question for the field is why this disorder develops in some, but not others, following severe trauma exposure....
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4,488 citations
"Disrupted amygdala-prefrontal funct..." refers background in this paper
...This is notable given that lower education level may be a risk factor for PTSD (Brewin et al., 2000)....
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3,911 citations
"Disrupted amygdala-prefrontal funct..." refers methods in this paper
...…address the a priori prediction that the PTSD and TC groups would differ in amygdala activation, we additionally examined group differences using small-volume correction within a bilateral amygdala region of interest (ROI), defined anatomically using the SPM Anatomy Toolbox (Eickhoff et al., 2005)....
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...To address the a priori prediction that the PTSD and TC groups would differ in amygdala activation, we additionally examined group differences using small-volume correction within a bilateral amygdala region of interest (ROI), defined anatomically using the SPM Anatomy Toolbox (Eickhoff et al., 2005)....
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3,610 citations
"Disrupted amygdala-prefrontal funct..." refers background in this paper
...This region has served as a target for deep-brain stimulation in severe refractory depression, producing a marked reduction in symptoms and long-term remission (Holtzheimer et al., 2012; Mayberg et al., 2005)....
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