Journal ArticleDOI
DNAs catalyzing DNA nanoconstruction
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TLDR
An overview of recent progress in the development of DNA nanotechnology promoted by the DNA/RNA-cleaving DNAs is presented and an outlook of how the two seemingly distant types of DNA could further collide with and mutually benefit each other, leading to the unprecedented downstream applications in various areas is provided.About:
This article is published in Chem.The article was published on 2021-10-14. It has received 11 citations till now. The article focuses on the topics: DNA origami & DNA nanotechnology.read more
Citations
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Journal ArticleDOI
Self-Assembly of DNA Molecules: Towards DNA Nanorobots for Biomedical Applications
TL;DR: In this paper, the authors proposed a scalable and cost-efficient method to control DNA nanorobots' stability, cargo loading and release, analyte binding, and dynamic switching.
Journal ArticleDOI
DNA-Based Molecular Machines
TL;DR: In this paper , the authors highlight the potential and strategies to construct artificial molecular machines using double-stranded DNA, functional nucleic acids, and DNA frameworks, which enable improved control over reaction pathways and motion behaviors.
Journal ArticleDOI
Spatial- and Valence-Matched Neutralizing DNA Nanostructure Blocks Wild-Type SARS-CoV-2 and Omicron Variant Infection
Shuang Wan,Siwen Liu,Miao Sun,Jialu Zhang,Xinyu Wei,Ting Song,Yuhao Li,Xinyang Liu,Honglin Chen Chen,Chaoyong James Yang,Yanling Song +10 more
TL;DR: The present design ensures improved binding affinity and neutralizing activity against SARS-CoV-2 and its varied mutant strains, particularly the current Omicron variant, that are evasive of the majority of existing neutralizing antibodies.
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Spherical nucleic acids-based biosensors for cancer biomarkers detection
TL;DR: Spherical nucleic acids (SNAs) are three-dimensional and polyvalent nanostructures with highly oriented and densely arranged nucleic acid shell attached to the surface of nanomaterials cores as discussed by the authors .
Journal ArticleDOI
Principles and Applications of Liquid‐Environment Atomic Force Microscopy
TL;DR: A review on the development history of liquid-environment atomic force microscopy (LE•AFM) can be found in this article , with an emphasis on challenges posed by liquid environments and corresponding solutions.
References
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Journal ArticleDOI
Folding DNA to create nanoscale shapes and patterns
TL;DR: This work describes a simple method for folding long, single-stranded DNA molecules into arbitrary two-dimensional shapes, which can be programmed to bear complex patterns such as words and images on their surfaces.
Journal ArticleDOI
DNA in a material world
TL;DR: The specific bonding of DNA base pairs provides the chemical foundation for genetics and this powerful molecular recognition system can be used in nanotechnology to direct the assembly of highly structured materials with specific nanoscale features, as well as in DNA computation to process complex information.
Journal ArticleDOI
Self-assembly of DNA into nanoscale three-dimensional shapes
Shawn M. Douglas,Hendrik Dietz,Tim Liedl,Björn Högberg,Franziska Graf,Franziska Graf,William M. Shih,William M. Shih +7 more
TL;DR: This work demonstrates the design and assembly of nanostructures approximating six shapes—monolith, square nut, railed bridge, genie bottle, stacked cross, slotted cross, and heterotrimeric wireframe icosahedra with precisely controlled dimensions.
Journal ArticleDOI
A General Purpose RNA-Cleaving DNA Enzyme
TL;DR: An in vitro selection procedure was used to develop a DNA enzyme that can be made to cleave almost any targeted RNA substrate under simulated physiological conditions, and its activity is dependent on the presence of Mg2+ ion.
Journal ArticleDOI
A DNA enzyme that cleaves RNA
TL;DR: Using in vitro selection techniques, a DNA enzyme is obtained that catalyzes the Pb(2+)-dependent cleavage of an RNA phosphoester in a reaction that proceeds with rapid turnover, and compares favorably to that of known RNA enzymes.
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