Journal ArticleDOI
Does Rejection Hurt? An fMRI Study of Social Exclusion
Naomi I. Eisenberger,Naomi I. Eisenberger,Matthew D. Lieberman,Matthew D. Lieberman,Kipling D. Williams,Kipling D. Williams +5 more
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TLDR
A neuroimaging study examined the neural correlates of social exclusion and tested the hypothesis that the brain bases of social pain are similar to those of physical pain, suggesting that RVPFC regulates the distress of socialclusion by disrupting ACC activity.Abstract:
A neuroimaging study examined the neural correlates of social exclusion and tested the hypothesis that the brain bases of social pain are similar to those of physical pain. Participants were scanned while playing a virtual ball-tossing game in which they were ultimately excluded. Paralleling results from physical pain studies, the anterior cingulate cortex (ACC) was more active during exclusion than during inclusion and correlated positively with self-reported distress. Right ventral prefrontal cortex (RVPFC) was active during exclusion and correlated negatively with self-reported distress. ACC changes mediated the RVPFC-distress correlation, suggesting that RVPFC regulates the distress of social exclusion by disrupting ACC activity.read more
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疟原虫var基因转换速率变化导致抗原变异[英]／Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A
TL;DR: PfPMP1）与感染红细胞、树突状组胞以及胎盘的单个或多个受体作用，在黏附及免疫逃避中起关键的作�ly.
Journal ArticleDOI
Dissociable Intrinsic Connectivity Networks for Salience Processing and Executive Control
William W. Seeley,Vinod Menon,Alan F. Schatzberg,Jennifer Keller,Gary H. Glover,Heather A. Kenna,Allan L. Reiss,Michael D. Greicius +7 more
TL;DR: Two distinct networks typically coactivated during functional MRI tasks are identified, anchored by dorsal anterior cingulate and orbital frontoinsular cortices with robust connectivity to subcortical and limbic structures, and an “executive-control network” that links dorsolateral frontal and parietal neocortices.
Journal ArticleDOI
How do you feel--now? The anterior insula and human awareness.
TL;DR: New findings suggest a fundamental role for the AIC (and the von Economo neurons it contains) in awareness, and thus it needs to be considered as a potential neural correlate of consciousness.
Journal ArticleDOI
An Integrative Theory of Locus Coeruleus-Norepinephrine Function: Adaptive Gain and Optimal Performance.
TL;DR: In this article, the locus coeruleus-norepinephrine (LC-NE) system plays a more complex and specific role in the control of behavior than investigators previously thought.
Journal ArticleDOI
Meeting of minds: the medial frontal cortex and social cognition.
David M. Amodio,Chris D. Frith +1 more
TL;DR: This work reviews the emerging literature that relates social cognition to the medial frontal cortex and proposes a theoretical model of medial frontal cortical function relevant to different aspects of social cognitive processing.
References
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疟原虫var基因转换速率变化导致抗原变异[英]／Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A
TL;DR: PfPMP1）与感染红细胞、树突状组胞以及胎盘的单个或多个受体作用，在黏附及免疫逃避中起关键的作�ly.
Journal ArticleDOI
Cognitive and emotional influences in anterior cingulate cortex
TL;DR: Various findings are reviewed in relation to the idea that ACC is a part of a circuit involved in a form of attention that serves to regulate both cognitive and emotional processing, and how the success of this regulation in controlling responses might be correlated with cingulate size.
Journal ArticleDOI
Improved assessment of significant activation in functional magnetic resonance imaging (fMRI) : use of a cluster-size threshold
Steven D. Forman,Jonathan D. Cohen,Mark Fitzgerald,William F. Eddy,Mark A. Mintun,Douglas C. Noll +5 more
TL;DR: In this article, an alternative approach, which relies on the assumption that areas of true neural activity will tend to stimulate signal changes over contiguous pixels, is presented, which can improve statistical power by as much as fivefold over techniques that rely solely on adjusting per pixel false positive probabilities.
Journal ArticleDOI
Pain affect encoded in human anterior cingulate but not somatosensory cortex.
TL;DR: These findings provide direct experimental evidence in humans linking frontal-lobe limbic activity with pain affect, as originally suggested by early clinical lesion studies.
Journal ArticleDOI
Cyberostracism: Effects of being ignored over the Internet.
TL;DR: The more participants were ostracized, the more they reported feeling bad, having less control, and losing a sense of belonging, as well as supporting K. D. Williams's need threat theory of ostracism.
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