Dual mode of action of Bt proteins: protoxin efficacy against resistant insects
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Cites background from "Dual mode of action of Bt proteins:..."
...Conversely, they are consistent with the proposition that the C-terminal regions of protoxins contribute to the binding and toxicity of Cry proteins (18, 21)....
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...Furthermore, both forms promoted different post-binding events in the toxic pathway; two different pathways of oligomerization and pore formation have been described that are based on the interaction of protoxin or the activated toxin with the CAD receptor (18, 21)....
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Cites background from "Dual mode of action of Bt proteins:..."
...It is theorized that bacterial production of protoxins is a strategy to impede resistance development [51]....
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...In fact, in some cases, the protoxin was more effective than the activated toxin [51,53]....
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References
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