Journal ArticleDOI
Dual-Stimuli Responsive Single-Chain Polymer Folding via Intrachain Complexation of Tetramethoxyazobenzene and β-Cyclodextrin.
Daniel C. Lee,Kathryn N. Guye,Rajan K. Paranji,Kacper Lachowski,Lilo D. Pozzo,David S. Ginger,Suzie H. Pun +6 more
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TLDR
In this article, a triblock polymer with asymmetric tetramethoxyazobenzene (TMAB) and β-cyclodextrin functionalization was synthesized and characterized.Abstract:
We synthesize and characterize a triblock polymer with asymmetric tetramethoxyazobenzene (TMAB) and β-cyclodextrin functionalization, taking advantage of the well-characterized azobenzene derivative-cyclodextrin inclusion complex to promote photoresponsive, self-contained folding of the polymer in an aqueous system. We use 1H NMR to show the reversibility of (E)-to-(Z) and (Z)-to-(E) TMAB photoisomerization, and evaluate the thermal stability of (Z)-TMAB and the comparatively rapid acid-catalyzed thermal (Z)-to-(E) isomerization. Important for its potential use as a functional material, we show the photoisomerization cyclability of the polymeric TMAB chromophore and calculate isomerization quantum yields by extinction spectroscopy. To verify self-inclusion of the polymeric TMAB and cyclodextrin, we use two-dimensional 1H NOESY NMR data to show proximity of TMAB and cyclodextrin in the (E)-state only; however, (Z)-TMAB is not locally correlated with cyclodextrin. Finally, the observed decrease in photoisomerization quantum yield for the dual-functionalized polymer compared to the isolated chromophore in an aqueous solution confirms TMAB and β-cyclodextrin not only are in proximity to one another, but also form the inclusion complex.read more
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pH-Triggered Transition from Micellar Aggregation to a Host-Guest Complex Accompanied by a Color Change.
TL;DR: In this article , a pH-triggered transition from micellar aggregation to a host-guest complex was achieved based on the supramolecular interactions between calixpyridinium and pyrroloquinoline quinone disodium salt (PQQ-2Na) accompanied by a color change.
Journal ArticleDOI
Multiple Effects of an Anionic Cyclodextrin Macrocycle on the Reversible Isomerization of a Photoactive Guest Dye.
TL;DR: In this article , the effects of an anionic cyclodextrin host (sulfated-βCD, SCD) on the photoisomerization and protonation equilibrium of an important hemicyanine dye (trans-4]-4-(dimethylamino)styryl]-1-methylpyridinium iodide, DSP).
Journal ArticleDOI
Tetrafluorinated versus hydrogenated azobenzene polymers in water: access to visible-light stimulus at the expense of responsiveness
Camille Courtine,Pierre-Louis Brient,Inés Hamouda,Nicolas Pataluch,Pierre Lavedan,Jean-Luc Putaux,Camille Chatard,Céline Galés,Anne-Françoise Mingotaud,N Lauth de Viguerie,Erwan Nicol +10 more
References
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Journal ArticleDOI
Stimuli-responsive nanocarriers for drug delivery
TL;DR: Recent advances in the design of nanoscale stimuli-responsive systems that are able to control drug biodistribution in response to specific stimuli, either exogenous (variations in temperature, magnetic field, ultrasound intensity, light or electric pulses) or endogenous (changes in pH, enzyme concentration or redox gradients).
Journal ArticleDOI
Photoisomerization in different classes of azobenzene
TL;DR: This critical review details the studies completed to date on the 3 main classes of azobenzene derivatives and explains the mechanism behind the isomerization mechanism.
Journal ArticleDOI
NMR Studies of Cyclodextrins and Cyclodextrin Complexes
Journal ArticleDOI
Stimuli-responsive polymers and their applications
TL;DR: Recent advances in the areas of sensing and biosensing, drug delivery, and actuators are reviewed, and the group's work on poly(N-isopropylacrylamide)-based microgels and assemblies is highlighted.
Journal ArticleDOI
Protein folding studied by single-molecule FRET.
TL;DR: Single-molecule fluorescence studies are still in their infancy and have already produced novel and important information on current issues in protein folding that has been impossible or difficult to obtain from ensemble measurements.
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