Journal ArticleDOI
Early autologous fresh whole blood transfusion leads to less allogeneic transfusions and is safe.
Peter Rhee,Kenji Inaba,Viraj Pandit,Mazhar Khalil,Stefano Siboni,Gary Vercruysse,Narong Kulvatunyou,Andrew Tang,Anum Asif,Terence O'Keeffe,Bellal Joseph +10 more
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TLDR
The autologous transfusion of the patient’s shed blood collected through chest tubes for hemothorax was found to be safe without complications in this study and would help in designing larger prospective multicenter studies to determine whether this practice is truly safe and effective.Abstract:
BACKGROUNDThe practice of transfusing ones’ own shed whole blood has obvious benefits such as reducing the need for allogeneic transfusions and decreasing the need for other fluids that are typically used for resuscitation in trauma. It is not widely adopted in the trauma setting because of the concread more
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Journal ArticleDOI
Allogeneic Blood Transfusion Increases the Risk of Postoperative Bacterial Infection: A Meta-Analysis: [2002][A-423]
TL;DR: It is demonstrated that allogeneic blood transfusion is a greater risk factor in the traumatically injured patient when compared with the elective surgical patient for the development of postoperative bacterial infection.
Journal ArticleDOI
Traumatic Hemothorax Blood Contains Elevated Levels of Microparticles that are Prothrombotic but Inhibit Platelet Aggregation
Thomas A. Mitchell,Maryanne C. Herzig,Chriselda G. Fedyk,Marc A. Salhanick,Aaron T. Henderson,Bijaya K. Parida,Nicolas Prat,Daniel L. Dent,Martin G. Schwacha,Andrew P. Cap +9 more
TL;DR: Autologous transfusion of shed traumatic hemothorax blood may induce a range of undesirable effects in patients with acute traumatic coagulopathy, and plasma hypercoagulability is induced that is likely related to increased tissue factor and phosphatidylserine expression originating from cell-derived MP.
Journal ArticleDOI
The European guideline on management of major bleeding and coagulopathy following trauma: sixth edition
Rolf Rossaint,Arash Afshari,Bertil Bouillon,Vladimir Cerny,Diana Cimpoesu,Nicola Curry,Jacques Duranteau,Daniela Filipescu,Oliver Grottke,Lars Grønlykke,Anatole Harrois,Beverley J. Hunt,Alexander Kaserer,Radko Komadina,Mikkel Herold Madsen,Marc Maegele,Lidia Mora,Louis Riddez,Carolina S Romero,Charles Marc Samama,Jean Louis Vincent,Sebastian Wiberg,Donat R. Spahn +22 more
TL;DR: The pan-European, multidisciplinary Task Force for Advanced Bleeding Care in Trauma included representatives from six European professional societies and convened to assess and update the previous version of this guideline using a structured, evidence-based consensus approach as mentioned in this paper .
Journal ArticleDOI
Shed Pleural Blood from Traumatic Hemothorax Contains Elevated Levels of Pro-Inflammatory Cytokines.
Marc A. Salhanick,Valere G. Sams,Heather F. Pidcoke,Chriselda G. Fedyk,Michael R. Scherer,Michael A. Dubick,Daniel L. Dent,Andrew P. Cap,Martin G. Schwacha +8 more
TL;DR: USHB, even collected within the accepted four-hour window, contains significantly elevated cytokine levels, suggesting the potential for deleterious effects from autotransfusion.
References
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Journal ArticleDOI
The Ratio of Blood Products Transfused Affects Mortality in Patients Receiving Massive Transfusions at a Combat Support Hospital
Matthew A. Borgman,Philip C. Spinella,Jeremy G. Perkins,Kurt W. Grathwohl,Thomas Repine,Alec C. Beekley,James A. Sebesta,Donald H. Jenkins,Charles E. Wade,John B. Holcomb +9 more
TL;DR: In patients with combat-related trauma requiring massive transfusion, a high 1:1.4 plasma to RBC ratio is independently associated with improved survival to hospital discharge, primarily by decreasing death from hemorrhage.
Journal ArticleDOI
2011 Update to The Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists Blood Conservation Clinical Practice Guidelines
Victor A. Ferraris,Jeremiah R. Brown,George J. Despotis,John W. Hammon,T. Brett Reece,Sibu P. Saha,Howard K. Song,Ellen R. Clough,Linda Shore-Lesserson,Lawrence T. Goodnough,C. David Mazer,Aryeh Shander,Mark Stafford-Smith,Jonathan H. Waters,Robert A. Baker,Timothy A. Dickinson,Daniel J. Fitzgerald,Donald S. Likosky,Kenneth G. Shann +18 more
TL;DR: Much has changed since the previously published 2007 STS blood management guidelines and this document contains new and revised recommendations.
Journal ArticleDOI
Increased plasma and platelet to red blood cell ratios improves outcome in 466 massively transfused civilian trauma patients
John B. Holcomb,Charles E. Wade,Joel E. Michalek,Gary B. Chisholm,Lee Ann Zarzabal,Martin A. Schreiber,Ernest A. Gonzalez,Gregory J. Pomper,Jeremy G. Perkins,Phillip C. Spinella,Kari L. Williams,Myung S. Park +11 more
TL;DR: The combination of high plasma and high platelet to RBC ratios were associated with decreased truncal hemorrhage, increased 6-hour, 24 hours, and 30-day survival, and increased intensive care unit, ventilator, and hospital-free days, with no change in multiple organ failure deaths.
Journal ArticleDOI
Allogeneic blood transfusion increases the risk of postoperative bacterial infection: a meta-analysis.
TL;DR: It is demonstrated that allogeneic blood transfusion is a greater risk factor in the traumatically injured patient when compared with the elective surgical patient for the development of postoperative bacterial infection.
Reference EntryDOI
Cell salvage for minimising perioperative allogeneic blood transfusion
TL;DR: The results suggest cell salvage is efficacious in reducing the need for allogeneic red cell transfusion in adult elective cardiac and orthopaedic surgery and the methodological quality of trials was poor.