Effect of body mass index, body composition, age and menopause on total body bone mineral density in Indian women
07 Aug 2002-pp 251-252
TL;DR: Bone mineral density measurement using dual energy X-ray absorptiometry (DEXA) has great clinical significance in the early detection and diagnosis of osteoporosis and the effect of age and menopause in Indian women is studied.
Abstract: Bone mineral density (BMD) measurement using dual energy X-ray absorptiometry (DEXA) has great clinical significance in the early detection and diagnosis of osteoporosis. In this study we evaluated the correlation of body mass index (BMI) and body composition on BMD and studied the effect of age and menopause in Indian women. Data on age, menopausal status, body mass index and body composition (tissue mass, fat tissue mass, lean body mass and bone mineral content) obtained from DEXA were collected from 24 pre-menopausal women (age 23-50) and 31 post-menopausal women (age 42-79). Women with high BMI are found to have greater BNID compared to that with lower BMI. Lean body mass showed strong correlation with BMD and a significant predictor (P<0.0001) of total BMID compared to fat mass. Average BNID in arms is found to be low when compared to pelvis and spine, but bone loss with age is found to be high in pelvis and spine. Age is negatively correlated to BMD and found very significant in post-menopausal women (P<0.0005) compared to pre-menopausal women (P<0.04). Bone mineral loss is found to be at higher rate immediately after menopause.
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Book•
15 Jan 1995
TL;DR: This chapter discusses the management of the patient with osteoporosis and the biomechanical markers of bone turnover, as well as the cells of bone and the biochemistry of bone bone remodelling and bone structure, which play a role in the development of fractures.
Abstract: Part 1 Basic science: the cells of bone the biochemistry of bone bone remodelling and bone structure the biomechanics of fractures. Part 2 Pathophysiology: inadequate peak bone mass sex steroid deficiency age-related factors sporadic factors. Part 3 Clinical presentation: clinical spectrum of osteoporosis epidemiology of fractures. Part 4 Diagnosis: vertebral morphometry and radiology bone densitometry and ultrasonography bone histomorhometry biomechanical markers of bone turnover. Part 5 Management: prevention management of menopausal-related problems drug therapy - calcium, oestrogen and Vitamin D metabolites drug therapy - calcitonin, bisphosphonates, anabolic steroids drug therapy - formation-stimulating regimens physical therapy and rehabilitation design and operation of an osteoporosis clinic practical management of the patient with osteoporosis.
601 citations
Journal Article•
119 citations
TL;DR: In this article, the authors used dual energy X-ray absorptiometry (DXA) at the radius (proximal site), lumbar spine, femoral neck, and total proximal femur regions in 537 consecutive white females age 50 and older referred by community physicians for bone densitometry.
53 citations
Journal Article•
TL;DR: The speed of sound and the broadband ultrasound attenuation, as determined by quantitative ultrasound at the calcaneum, were correlated with the bone mineral density measurements using dual-energy X-ray absorptiometry at the femoral neck and the lumbar spine in 110 females, suggesting that quantitative ultrasound may be reasonably accurate and useful for the assessment of osteoporosis.
Abstract: The speed of sound (SOS) and the broadband ultrasound attenuation (BUA), as determined by quantitative ultrasound at the calcaneum, were correlated with the bone mineral density (BMD) measurements using dual-energy X-ray absorptiometry at the femoral neck and the lumbar spine in 110 females. There were moderate correlations of 0.629, 0.623 and 0.594 between the BMD at the anterior-posterior lumbar spine, lateral lumbar spine and femoral neck with the SOS at the calcaneum (all P < 0.001). The corresponding correlations with BUA were 0.646, 0.643 and 0.628 respectively (all P < 0.001). This suggests that quantitative ultrasound may be reasonably accurate and useful for the assessment of osteoporosis.
12 citations