Effect of catecholamine-receptor stimulating agents on blood pressure after local application in the nucleus tractus solitarii of the medulla oblongata.
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TLDR
The present data suggest that the catecholaminergic receptors in the A2-region of the NTS differ from the classic vascular alpha-receptor and that the NTS also may contain structures which can antagonize the decrease in blood pressure.About:
This article is published in European Journal of Pharmacology.The article was published on 1979-04-01 and is currently open access. It has received 167 citations till now. The article focuses on the topics: Decreased blood pressure & Dopamine.read more
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Distribution of α2 agonist binding sites in the rat and human central nervous system: Analysis of some functional, anatomic correlates of the pharmacologic effects of clonidine and related adrenergic agents
TL;DR: These functional, anatomical and neurochemical correlates of the alpha 2 binding site distribution establish a neurological basis for the complex pharmacological effects of centrally acting alpha 2 agonists.
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Distribution of glucagonlike peptide I (GLP‐I), glucagon, and glicentin in the rat brain: An immunocytochemical study
TL;DR: The anatomical distribution of three different antigenic determinants of pancreatic proglucagon‐‐glucagonlike peptide I (GLP‐I), glucagon, and glicentin was mapped in the brain of colchicine‐treated rats by immunocytochemistry using the avidin‐biotin‐peroxidase method.
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Growth hormone and other responses to clonidine in patients with endogenous depression.
TL;DR: The growth hormone response to clonidine was significantly less in 10 drug-free patients with endogenous depression than in normal subjects who were individually matched with the patients for age and sex, indicating a defect at central adrenoceptors at least in neuroendocrine systems.
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Neurochemical modulation of cardiovascular control in the nucleus tractus solitarius.
Andrew J Lawrence,Bevyn Jarrott +1 more
TL;DR: This review will attempt to collate the current knowledge regarding the roles of neuromodulators in the NTS, the receptor types involved in mediating observed responses and the degree of importance of such neurochemicals in the tonic regulation of the cardiovascular system.
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Effects of chronic morphine administration on mu opioid receptor-stimulated [35S]GTPgammaS autoradiography in rat brain.
TL;DR: Data indicate that chronic morphine administration results in reductions in mu opioid activation of G-proteins in specific brainstem nuclei involved in physiological homeostasis and autonomic function, which may have implications in the development of opiate tolerance and physical dependence.
References
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Journal Article
Evidence for the existence of monoamine-containing neurons in the central nervous system. i. demonstration of monoamines in the cell bodies of brain stem neurons.
Dahlstroem A,Fuxe K +1 more
Journal ArticleDOI
Evidence for the existence of monoamine neurons in the central nervous system. 3. the monoamine nerve terminal.
TL;DR: All the data strongly support the view that the specific central neurons giving rise to the terminals are monoaminergic, i.e. function by releasing their amines from the synaptic terminals, Consequently, DA, NA and 5-HT seem to be central neurotransmitters.
Journal Article
Evidence for the existence of monoamine neurons in the central nervous system. iv. distribution of monoamine nerve terminals in the central nervous system.
Journal Article
Dopamine (3-hydroxytyramine) and brain function
TL;DR: A good case can be made for the concept that the physiological activity of the brain dopamine is quite different from that of brain norepinephrine, although there are as yet no experiments to positively show that dopamine is a true neuro-transmitter substance in the brain.
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Evidence for the existence of monoamine-containing neurons in the central nervous system. i. demonstration of monoamines in the cell bodies of brain stem neurons.
Dahlstroem A,Fuxe K +1 more