Effect of exogenous melatonin on X-ray induced cellular toxicity in lymphatic tissue of Indian tropical male squirrel, Funambulus pennanti.
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54 citations
Cites background from "Effect of exogenous melatonin on X-..."
...In the case of mature T lymphocytes, exogenous melatonin was able to diminish the cytotoxicity of x-ray irradiation (45) or idarubicin (46)....
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48 citations
43 citations
Cites background from "Effect of exogenous melatonin on X-..."
...organs including the spleen (8, 11, 22), liver (5, 9, 20),...
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...Melatonin (N-acetyl-5-methoxytryptamine) is an endogenous compound synthesized by the pineal gland in the human brain (10-12)....
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41 citations
Cites background from "Effect of exogenous melatonin on X-..."
...06 Gy X-ray-induced cellular toxicity [31]....
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...spinal cord [24e26], lens [27], liver [28e30], spleen [2,31,32], lung, colon and ileum [29]....
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...[2,31,32] studies when reported that pre-treatment with melatonin increased lymphocyte count in irradiated groups....
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37 citations
References
18,580 citations
"Effect of exogenous melatonin on X-..." refers methods in this paper
...The radical scavenging activity of antioxidants for ABTS radical cations was measured according to the method of Re et al. (1999)....
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9,597 citations
"Effect of exogenous melatonin on X-..." refers methods in this paper
...OH DNA ends accompanying chromatin fragmentation can be detected by the TUNEL assay (Gavrieli et al. 1992)....
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...Free 30-OH DNA ends accompanying chromatin fragmentation can be detected by the TUNEL assay (Gavrieli et al. 1992)....
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1,824 citations
"Effect of exogenous melatonin on X-..." refers background in this paper
...Melatonin regulates antioxidant enzyme gene expression and activity with activation of MT1/2 receptors, via G inhibitory (Gi) protein (Mayo et al. 2002, Rodriguez et al. 2004)....
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...…discovery of melatonin as a direct free radical scavenger (Tan et al. 1993) and as an indirect antioxidant via its stimulatory actions on antioxidative enzymes (Reiter et al. 2000, Rodriguez et al. 2004) has greatly increased interest in the use of this agent in experimental and clinical settings....
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...The oxidative status of the cell is the primary factor regulating gene expression and activity of these enzymes (Rodriguez et al. 2004)....
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1,495 citations
1,074 citations
"Effect of exogenous melatonin on X-..." refers background in this paper
...…discovery of melatonin as a direct free radical scavenger (Tan et al. 1993) and as an indirect antioxidant via its stimulatory actions on antioxidative enzymes (Reiter et al. 2000, Rodriguez et al. 2004) has greatly increased interest in the use of this agent in experimental and clinical settings....
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