Journal ArticleDOI
Effect of heavy ion irradiation on DNA DSB repair in Methanosarcina barkeri.
Shaon RayChaudhuri,Parimal Karmakar,Dharamainder Choudhary,A. Sarma,Ashoke Ranjan Thakur,Ashoke Ranjan Thakur +5 more
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TLDR
DNA double strand break repairing ability of mesophilic archaea Methanosarcina barkeri (DSM 804) was studied using (7)Li, (12)C and (16)O heavy ions and compared with that of (60)Co gamma-rays.About:
This article is published in Anaerobe.The article was published on 2003-02-01. It has received 5 citations till now. The article focuses on the topics: Methanosarcina barkeri.read more
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Journal ArticleDOI
Response of the Hyperthermophilic Archaeon Sulfolobus solfataricus to UV Damage
Sabrina Fröls,Paul M. K. Gordon,Mayi Arcellana Panlilio,Iain G. Duggin,Stephen D. Bell,Christoph Wilhelm Sensen,Christa Schleper +6 more
TL;DR: In this paper, high-density DNA microarrays were used to characterize the genome-wide transcriptional response of the hyperthermophilic, aerobic crenarchaeote Sulfolobus solfataricus to UV damage.
Journal ArticleDOI
Desiccation as a long-term survival mechanism for the archaeon Methanosarcina barkeri.
TL;DR: After desiccation M. barkeri has the innate capability to survive extended periods of exposure to air and lethal temperatures, and the protection mechanisms are likely adequate to maintain cell viability during periodic exposure events.
Journal ArticleDOI
Low-dose carbon ion irradiation effects on DNA damage and oxidative stress in the mouse testis
TL;DR: In this paper, the effects of low-dose carbon ion irradiation on reproductive system of mice were investigated by measuring DNA double-strand breaks (DNA DSBs) and oxidative stress parameters including malondialdehyde (MDA) content, superoxide dismutase (SOD) activity, and testis weight and sperm count at 12h, 21d and 35d after irradiation in mouse testis.
Journal ArticleDOI
Radiation Induced DNA Double Strand Break Studies of a Metal Sensitive Novel Bacterial Isolate from East Calcutta Wetland
TL;DR: The strain was one of the members of the group of uncultivated bacterium as evident from phylogenetic analysis, thus indicating the successful cultivation of an as yet uncultivable novel microbe and also the non-specific growth of microbes in prescribed medium.
References
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Journal ArticleDOI
Frequencies of Complex Chromosome Exchange Aberrations Induced by 238Pu α-particles and Detected by Fluorescence in Situ Hybridization Using Single Chromosome-specific Probes
TL;DR: The high level of complex aberrations observed after alpha-particle irradiation indicates that, when chromosome domains are traversed by high linear energy transfer alpha- particle tracks, there is an enhanced probability of production of multiple localized double-strand breaks leading to more complicated interactions.
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DNA damage induced by radiation of different linear energy transfer: initial fragmentation.
TL;DR: A significant non-random contribution to the number of dsb after irradiation with high-LET was confirmed by detailed fragment analysis using pulsed-field gel electrophoresis, and the LET had a strong influence on the initial DNA fragment distribution, and hence also on the induction yields measured.
Journal ArticleDOI
DNA Double-Strand Breaks Induced by High-Energy Neon and Iron Ions in Human Fibroblasts. I. Pulsed-Field Gel Electrophoresis Method
TL;DR: It is concluded that either the initial yield of DNA double-strand breaks induced by the high-energy particles is lower than the yield for X rays, or the breaks induce by heavy ions are present in clusters that cannot be resolved with the technique used.
Journal ArticleDOI
Charged-particle mutagenesis: I. Cytotoxic and mutagenic effects of high- LET charged iron particles on human skin fibroblasts
TL;DR: Cytotoxic and mutagenic effects of high-LET charged iron (56Fe) particles were measured quantitatively using primary cultures of human skin fibroblasts using 6-thio-guanine (6-TG) for selection and fitted by the linear model.
Journal ArticleDOI
Induction of chromosome aberrations in human cells by charged particles
TL;DR: Results of this study showed that complex aberrations have the highest RBE for radiation of high linear energy transfer (LET) for human lymphocytes, but for fibroblasts, the greatest effect was for incomplete exchanges.
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Promotion of double-strand break repair by human nuclear extracts preferentially involves recombination with intact homologous DNA.
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