Journal ArticleDOI
Effect of undecanoic acid on the production of exocellular lipolytic and keratinolytic enzymes by undecanoic acid-sensitive and -resistant strains of Trichophyton rubrum
S.K. Das,A.B. Banerjee +1 more
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TLDR
No exocellular keratinase could be detected in the udar strain which had very low capacity for invasion of keratinized tissue.Abstract:
Effects of undecanoic acid on exocellular lipase, phospholipase A and keratinase activities of wild type undecanoic acid-sensitive (udas) and an undecanoic acid-resistant mutant (udar) of Trichophyton rubrum (derived from the udas strain) were determined. Undecanoic acid inhibited the production of exocellular lipase and keratinase but stimulated the production of exocellular phospholipase A in T. rubrum udas. Undecanoic acid did not affect exocellular lipase production by T. rubrum udar. Lipase production by the udar mutant was lower than that of the udas parent. No exocellular keratinase could be detected in the udar strain which had very low capacity for invasion of keratinized tissue.read more
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Keratinolysis by poultry farm soil fungi.
Sanjana Kaul,Geeta Sumbali +1 more
TL;DR: Species of Chrysosporium, Malbranchea, Scopulariopsis, Microascus, and Gliocladium isolated from poultry farm soils were grown on two keratin media and all the test fungi could grow on keratin and degrade it, releasing sulphydryl-containing compounds detected as extracellular keratinase, cysteine and total proteins.
Journal ArticleDOI
Purification and partial characterization of an exocellular proteinase from Trichophyton rubrum
TL;DR: An exocellular proteinase produced by Trichophyton rubrum in a glucose-peptone broth was purified from lyophilized and dialysed culture filtrate of the dermatophyte and showed an alkaline pH optimum and was not activated by divalent metal ions but inhibited strongly by phenylmethylsulfonylfluoride.
Journal ArticleDOI
Current knowledge of host response in human tinea.
TL;DR: The known mechanisms and factors involved in human tinea and important for the host response are briefly delineated and Cellular defence mechanisms appear to be decisive for clearing of infection.
Journal ArticleDOI
Analysis of Trichophyton rubrum gene expression in response to cytotoxic drugs
F. G. Paião,Fernando Segato,Jeny R. Cursino-Santos,Nalu T. A. Peres,Nilce Maria Martinez-Rossi +4 more
TL;DR: In this paper, suppressive subtractive hybridization was used to isolate transcripts specifically upregulated during Trichophyton rubrum exposure to acriflavin, fluconazole, griseofulvin, terbinafine or undecanoic acid.
References
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Journal ArticleDOI
Decomposition of native keratin by streptomyces fradiae
TL;DR: Do the microorganisms decompose native keratin during their growth on keratinaceous substrates, or do they grow at the expense of nonkeratinaceous nutrients that are usually present as minor constituents of such substrates?
Journal ArticleDOI
In vitro hair cultures for differentiating between atypical isolates of Trichophyton mentagrophytes and Trichophyton rubrum.
Libero Ajello,Lucille K. Georg +1 more
TL;DR: Isolates of T. mentagrophytes and T. rubrum are encountered that cannot be distinguished from each other solely on the basis of morphological criteria.