Journal ArticleDOI
Effects of intranasal oxytocin on the neural basis of face processing in autism spectrum disorder
Gregor Domes,Markus Heinrichs,Ekkehardt Kumbier,Annette Grossmann,Karlheinz Hauenstein,Sabine C. Herpertz +5 more
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It is suggested that oxytocin might promote face processing and eye contact in individuals with ASD as prerequisites for neurotypical social interaction.About:
This article is published in Biological Psychiatry.The article was published on 2013-08-01. It has received 223 citations till now. The article focuses on the topics: Fusiform gyrus & Autism spectrum disorder.read more
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Vasopressin and oxytocin receptor systems in the brain: Sex differences and sex-specific regulation of social behavior.
Kelly M. Dumais,Alexa H. Veenema +1 more
TL;DR: This review discusses the evidence showing the presence or absence of sex differences in VP and OT receptors in rodents and humans, as well as showing new data of sexually dimorphic V1a receptor binding in the rat brain.
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Autism, oxytocin and interoception.
E. Quattrocki,Karl J. Friston +1 more
TL;DR: A model for impaired interoception giving rise to the autistic phenotype is proposed and how this analysis could suggest therapeutic strategies is described.
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Oxytocin enhances brain function in children with autism
Ilanit Gordon,Brent C. Vander Wyk,Randi H. Bennett,Cara Cordeaux,Molly V. Lucas,Jeffrey Eilbott,Orna Zagoory-Sharon,James F. Leckman,Ruth Feldman,Ruth Feldman,Kevin A. Pelphrey +10 more
TL;DR: It is found that intranasal administration of oxytocin enhances activity in the brain for socially meaningful stimuli and attenuates its response to nonsocially meaningful stimuli in children with autism spectrum disorder as measured via functional MRI.
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Autism Spectrum Disorder: Classification, diagnosis and therapy
TL;DR: Developing novel disease‐modifying therapies may prove to be the ultimate intervention for sustained improvement of symptoms in ASD.
Journal ArticleDOI
Oxytocin Enhances Social Recognition by Modulating Cortical Control of Early Olfactory Processing
Lars-Lennart Oettl,Namasivayam Ravi,Miriam Schneider,Max Scheller,Peggy Schneider,Mariela Mitre,Miriam da Silva Gouveia,Robert C. Froemke,Moses V. Chao,W. Scott Young,Andreas Meyer-Lindenberg,Valery Grinevich,Valery Grinevich,Roman Shusterman,Wolfgang Kelsch +14 more
TL;DR: It is observed that optogenetically induced oxytocin release enhanced olfactory exploration and same-sex recognition of adult rats and generates states for optimized information extraction in an early cortical top-down network that is required for social interactions with potential implications for sensory processing deficits in autism spectrum disorders.
References
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Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders
TL;DR: The revised interview has been reorganized, shortened, modified to be appropriate for children with mental ages from about 18 months into adulthood and linked to ICD-10 and DSM-IV criteria.
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The autism diagnostic observation schedule-generic: a standard measure of social and communication deficits associated with the spectrum of autism.
Catherine Lord,Susan Risi,Linda Lambrecht,Edwin H. Cook,Bennett L. Leventhal,Pamela C. DiLavore,Andrew Pickles,Michael Rutter +7 more
TL;DR: Algorithm sensitivities and specificities for autism and PD DNOS relative to nonspectrum disorders were excellent, with moderate differentiation of autism from PDDNOS.
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The ''Reading the Mind in the Eyes'' Test Revised Version: A Study with Normal Adults, and Adults with Asperger Syndrome or High-functioning Autism
TL;DR: The Revised Eyes Test has improved power to detect subtle individual differences in social sensitivity and was inversely correlated with the Autism Spectrum Quotient (the AQ), a measure of autistic traits in adults of normal intelligence.
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Oxytocin increases trust in humans
TL;DR: It is shown that intranasal administration of oxytocin, a neuropeptide that plays a key role in social attachment and affiliation in non-human mammals, causes a substantial increase in trust among humans, thereby greatly increasing the benefits from social interactions.