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Open AccessJournal ArticleDOI

Effects of prior influenza virus vaccination on maternal antibody responses: Implications for achieving protection in the newborns.

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TLDR
In this cohort of pregnant women, receipt of influenza vaccine the previous year predicted higher baseline antibody titers and decreased antibody responses at one month post-vaccination against all influenza strains, but prior maternal vaccination did not significantly affect either maternal antibody levels at delivery or antibody levels transferred to the neonate.
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This article is published in Vaccine.The article was published on 2017-09-18 and is currently open access. It has received 11 citations till now. The article focuses on the topics: Influenza vaccine & Seroconversion.

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Pathways linking childhood abuse history and current socioeconomic status to inflammation during pregnancy.

TL;DR: Pre-pregnancy BMI and interpersonal conflict are two independent mechanisms by which adversity is associated with increased inflammation during pregnancy, with implications for immune dysregulation during pregnancy.
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Influenza Vaccination, Pregnancy Safety, and Risk of Early Pregnancy Loss.

TL;DR: The study's reported observation is not definitive and needs be replicated in appropriately designed studies before changing clinical practice, and the lack of a biologically plausible mechanism for the suggested association between previous influenza vaccination and early pregnancy loss is of concern.
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Influenza in High-Risk Hosts—Lessons Learned from Animal Models

TL;DR: By using varied animal models, researchers have identified molecular mechanisms underpinning the increased likelihood for infection due to obesity and malnourishment, as well as insight into the role sex hormones play in antiviral immunity in males, in females, and across the life span.
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Influenza Vaccination Rates Among Parents and Health Care Personnel in a German Neonatology Department.

TL;DR: The influenza vaccine uptake rate of 10% in mothers of hospitalized newborns and HCP in neonatal units is disappointingly low, resulting in 90% of hospitalized neonates being potentially vulnerable to influenza infection at a time where the risk for influenza-related complication can be severe.
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The Effects of Birth Year, Age and Sex on Hemagglutination Inhibition Antibody Responses to Influenza Vaccination

TL;DR: Data suggest that HI antibody production, in response to influenza vaccination, is affected by factors related to age, sex, prior vaccination, deployment and birth year, and the magnitude of this antibody response is associated with the influenza strain that circulated following birth.
References
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Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices - United States, 2020-21 Influenza Season.

TL;DR: This report updates the 2017–18 recommendations of the Advisory Committee on Immunization Practices regarding the use of seasonal influenza vaccines in the United States and focuses on the recommendations for use of vaccines for the prevention and control of influenza during the 2018–19 season.
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Effectiveness of maternal influenza immunization in mothers and infants.

TL;DR: Inactivated influenza vaccine reduced proven influenza illness by 63% in infants up to 6 months of age and averted approximately a third of all febrile respiratory illnesses in mothers and young infants in Bangladesh.
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Antibody response to influenza vaccination in the elderly: a quantitative review.

TL;DR: It is concluded that the antibody response in the elderly is considerably lower than in younger adults, which highlights the need for more immunogenic vaccine formulations for the elderly.
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The Underrecognized Burden of Influenza in Young Children

TL;DR: Among young children, outpatient visits associated with influenza were 10 to 250 times as common as hospitalizations, and few influenza infections were recognized clinically.
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