Journal ArticleDOI
Eight-membered ring templates for stereoselective radical cyclizations
Reads0
Chats0
TLDR
The ratio of cyclization to reduction of the cyclodec-6-enylmethyl radical depends critically on the alkene geometry as mentioned in this paper, which is a structural feature of the taxane diterpenes.About:
This article is published in Tetrahedron Letters.The article was published on 1988-01-01. It has received 16 citations till now. The article focuses on the topics: Radical cyclization.read more
Citations
More filters
Journal ArticleDOI
Chemistry and Biology of Taxol
TL;DR: This account attempts to bring together in a cogent overview the chemistry and biology of taxol, one of the few organic compounds, which, like benzene and aspirin, is recognizable by name to the average citizen.
Journal ArticleDOI
The synthesis of carbocyclic eight-membered rings
Journal ArticleDOI
Free radicals in the synthesis of medium-sized rings
TL;DR: In this paper, free radical chemistry in the synthesis of seven-to-nine-membered rings is presented, and applications of free radical chemiques in the synthesisation of seven to nine-memered rings are discussed.
Journal ArticleDOI
Chemie und Biologie von Taxol
TL;DR: Taxus brevifolia, e.g., polyoxygeniertes Diterpen aus der Pazifischen Eibe, wurde in den spaten sechziger Jahren bei einer umfassenden Untersuchung pflanzlicher Stoffe auf antineoplastische Wirkstoffe entdeckt, an which es scheint, das die Medien aufmerksam geworden sind and jede neue Entwicklung gespannt er
Reference EntryDOI
Radical Cyclization Reactions
TL;DR: Radical cyclization reactions are among the most powerful and versatile methods for the construction of mono-and polycyclic systems as discussed by the authors, which offer high functional group tolerance and mild reaction conditions combined with high levels of regio- and stereochemistry.
References
More filters
Journal ArticleDOI
Highly efficient, practical approach to natural taxol
Jean Noel Denis,Andrew E. Greene,Daniel Guenard,Francoise Gueritte-Voegelein,Lydie. Mangatal,Pierre Potier +5 more
Journal ArticleDOI
Chemical consequences of conformation in macrocyclic compounds
W. Clark Still,Igor Galynker +1 more
TL;DR: In this paper, the conformational properties of medium and large-ring organic molecules have profound consequences on the stereochemical course of their chemical reactions, and the diastereomeric composition of the products was determined.
Journal ArticleDOI
Titanium-induced reductive coupling of carbonyls to olefins
Related Papers (5)
Formation of a trans-bicyclo[3.3.0]Octane by tandem anionic cyclization: evidence for the highly stereoselective irreversible nature of 5-hexen-1-yllithium cyclizations
Interconversion of bicyclooctadienes and cyclooctatrienes formed by intramolecular photocycloaddition of phenyl ketones containing remote double bonds
Peter J. Wagner,Keepyung Nahm +1 more