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El café y sus efectos en la salud cardiovascular y en la salud materna

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TLDR
La conclusion general es that el consumo of cafeina, hasta 300 mg/dia, no constituye un mayor riesgo of infarto al miocardio, of hipertension, o of modificacion of los niveles plasmaticos de indicadores of riesgos cardiovascular, como the proteina C reactiva y the homocisteina.
Abstract
La cafeina es el principal componente activo del cafe y los efectos del consumo de cafe se asocian mayoritariamente a la cafeina, una metilxantina que actua como antagonista de los receptores de adenina en el sistema nervioso. Son numerosos los efectos en la salud atribuidos a la cafeina, siendo algunos beneficos y otros deletereos: en la salud cardiovascular, diabetes tipo 2, tolerancia a la glucosa y sensibilidad a la insulina, en la cinosis hepatica y el carcinoma hepatocelular, entre otros efectos. Este articulo realiza una revision de dos aspectos de preocupacion en la salud publica relacionados con el consumo de cafe y la cafeina: su efecto en la salud cardiovascular y en la salud maternal (periodo perinatal). La conclusion general es que el consumo de cafeina, hasta 300 mg/dia, no constituye un mayor riesgo de infarto al miocardio, de hipertension, o de modificacion de los niveles plasmaticos de indicadores de riesgo cardiovascular, como la proteina C reactiva y la homocisteina. En relacion a la salud maternal, las conclusiones son similares, un consumo moderado de cafeina (300 mg/dia o menos) no constituye un riesgo de menor concepcion, de diabetes gestacional, de menor crecimiento fetal, o de defectos congenitos. La ausencia de riesgo, sin embargo, no constituye un estimulo al consumo de cafe durante el embarazo. Si el consumo de cafe por parte de la futura madre es moderado, puede considerarse la continuacion del consumo durante el embarazo bajo supervision medica

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Citations
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Anthropogenic contaminants of high concern: Existence in water resources and their adverse effects.

TL;DR: This work provides a detailed overview of ACs occurrence in water bodies along with their toxicological effect on living organisms and robust detection and removal strategies must be considered in the design of WWTPs and DWTPs.
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Caracterización fisicoquímica y microbiológica de aguas mieles del beneficio del café

TL;DR: In this paper, the authors evaluated the potential in the extraction of biocomponents in the coffee processing process using two water samples (M1, M2) and found mesophiles, coliforms and staphylococci in both samples.

Influencia de la fitohormona kinetina en el crecimiento de plántulas de Coffea arábiga L. injertadas sobre patrón robusta en vivero

TL;DR: The objective of determining the incidence of phytohormone kinetin in the growth of four varieties of Arabica coffee, grafted on robust pattern, was executed in the nursery of the experimental farm of the Southern State University of Manabi.
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Consumo de psicoestimulantes lícitos en estudiantes de doctorado en Medicina

TL;DR: The number of medical students dependent on tobacco increases as they advance in the clinical area, despite this, the percentage of UEES medicine students who smoke is almost half of the prevalence of smoking in young Latin Americans.
References
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Journal ArticleDOI

Caffeine metabolism, genetics, and perinatal outcomes: a review of exposure assessment considerations during pregnancy.

TL;DR: Research on the genetic polymorphisms affecting caffeine metabolism may further explain the potential effects of caffeine and its metabolites on perinatal outcomes.
Journal Article

Neuroprotective role of adenosine in the CNS.

TL;DR: It might be suggested that adenosine A2A receptor antagonists may represent a novel strategy in the therapeutic approach to pathologies characterized by acute or chronic neurodegenerative events, since they not only reverse motor impairment but can act as neuroprotective compunds by promoting cell survival.
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Caffeine effects on cardiovascular and neuroendocrine responses to acute psychosocial stress and their relationship to level of habitual caffeine consumption.

TL;DR: Results indicate that caffeine can potentiate both cardiovascular and neuroendocrine stress reactivity and that the habitual use of caffeine is not necessarily associated with the development of tolerance to these effects.
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Maternal Serum Paraxanthine, a Caffeine Metabolite, and the Risk of Spontaneous Abortion

TL;DR: It is suggested that moderate consumption of caffeine is unlikely to increase the risk of spontaneous abortion, and only extremely high serum paraxanthine concentrations are associated with spontaneous abortion.
Journal ArticleDOI

Heavy coffee consumption and plasma homocysteine: a randomized controlled trial in healthy volunteers

TL;DR: In this paper, the authors found that drinking large quantities of paper-filtered coffee raises fasting plasma concentrations of total homocysteine in healthy individuals, which is considered to be a strong risk factor for cardiovascular disease.