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Journal ArticleDOI

Electrowetting-based actuation of liquid droplets for microfluidic applications

Michael G. Pollack, +2 more
- 05 Sep 2000 - 
- Vol. 77, Iss: 11, pp 1725-1726
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TLDR
In this article, a microactuator for rapid manipulation of discrete microdroplets is presented, which is accomplished by direct electrical control of the surface tension through two sets of opposing planar electrodes fabricated on glass.
Abstract
A microactuator for rapid manipulation of discrete microdroplets is presented. Microactuation is accomplished by direct electrical control of the surface tension through two sets of opposing planar electrodes fabricated on glass. A prototype device consisting of a linear array of seven electrodes at 1.5 mm pitch was fabricated and tested. Droplets (0.7–1.0 μl) of 100 mM KCl solution were successfully transferred between adjacent electrodes at voltages of 40–80 V. Repeatable transport of droplets at electrode switching rates of up to 20 Hz and average velocities of 30 mm/s have been demonstrated. This speed represents a nearly 100-fold increase over previously demonstrated electrical methods for the transport of droplets on solid surfaces.

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Citations
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Journal ArticleDOI

Microfluidics: Fluid physics at the nanoliter scale

TL;DR: A review of the physics of small volumes (nanoliters) of fluids is presented, as parametrized by a series of dimensionless numbers expressing the relative importance of various physical phenomena as mentioned in this paper.
Journal ArticleDOI

Engineering flows in small devices

TL;DR: An overview of flows in microdevices with focus on electrokinetics, mixing and dispersion, and multiphase flows is provided, highlighting topics important for the description of the fluid dynamics: driving forces, geometry, and the chemical characteristics of surfaces.
Journal ArticleDOI

Electrowetting: from basics to applications

TL;DR: In this paper, the authors compare the various approaches used to derive the basic electrowetting equation, which has been shown to be very reliable as long as the applied voltage is not too high.
Journal ArticleDOI

Physics and applications of microfluidics in biology.

TL;DR: The focus of this review is microscale phenomena and the use of the physics of the scale to create devices and systems that provide functionality useful to the life sciences.
Journal ArticleDOI

Reactions in Droplets in Microfluidic Channels

TL;DR: Fundamental and applied research in chemistry and biology benefits from opportunities provided by droplet-based microfluidic systems, which enable the miniaturization of reactions by compartmentalizing reactions in droplets of femoliter to microliter volumes.
References
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Journal ArticleDOI

Electrochemical Principles for Active Control of Liquids on Submillimeter Scales

TL;DR: Electrochemical methods were combined with redox-active surfactants to actively control the motions and positions of aqueous and organic liquids on millimeter and smaller scales to guide droplets of organic liquids through simple fluidic networks.
Journal ArticleDOI

Electrostatic actuation of liquid droplets for micro-reactor applications

TL;DR: In this paper, a device for the electrostatic actuation of liquid droplets on a solid surface is developed, where arrays of electrodes are micro-fabricated on a substrate, which is covered by a hydrophobic layer.
Journal ArticleDOI

Microfabricated structures for integrated DNA analysis

TL;DR: A surface-tension-based pump able to move discrete nanoliter drops through enclosed channels using only local heating is described, which may provide significant improvements in DNA analysis speed, portability, and cost.
Journal ArticleDOI

Thermocapillary Pumping of Discrete Drops in Microfabricated Analysis Devices

TL;DR: The thermocapillary pumping TCP (TCP) as discussed by the authors is a non-mechanical pumping mechanism for dropping nanoliter and picoliter-sized drops of liquid within microfabricated flow channels.
Journal ArticleDOI

Electrowetting of water and aqueous solutions on poly(ethylene terephthalate) insulating films

TL;DR: In this article, the authors show that the electrowetting effect can decrease contact angles by more than 30° under applied voltages of 200 V eff, but for high voltage, the electrowsetting saturates, with other poly(ethylene terephthalate) films.
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