Elucidation of extracellular matrix mechanics from muscle fibers and fiber bundles.
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TLDR
A new method to quantify viscoelastic ECM modulus is presented by combining tests of single muscle fibers and fiber bundles, which demonstrate that ECM is a highly nonlinearly elastic material, while muscle fibers are linearly elastic.About:
This article is published in Journal of Biomechanics.The article was published on 2011-02-24 and is currently open access. It has received 156 citations till now. The article focuses on the topics: Skeletal muscle.read more
Citations
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Aging and the Pelvic Floor
Karla Wente,Christina Dolan +1 more
TL;DR: There are numerous unique considerations in the treatment of the older adult with pelvic floor dysfunction, due to muscular, hormonal, and neurological changes with age, and Conservative management, including physical therapy, should be considered prior to surgical intervention.
Lateral force transmission between human tendon fascicles
Bjarki Haraldsson,Per Aagaard,Klaus Qvortrup,Jens Bojsen-Møller,Michael Krogsgaard,S. O. A. Koskinen,Michael Kjaer,Peter Magnusson +7 more
TL;DR: The present data demonstrate that lateral force transmission between adjacent collagen fascicles in human tendons is small or negligible, suggesting that tendon fascicles largely act as independent structures and that force transmission principally takes place within the individual fascicles.
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Correlation Between Muscle Structures and Electrical Properties of the Tibialis Anterior in Subacute Stroke Survivors: A Pilot Study.
TL;DR: A correlation between the EIM and the ultrasonography parameters at different joint angles was demonstrated, indicating that both methods could jointly be applied in patients with stroke to detect changes in the muscle inherent properties and muscle architecture.
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Non-invasive assessment of skeletal muscle fibrosis in mice using nuclear magnetic resonance imaging and ultrasound shear wave elastography.
A.B. Martins-Bach,Damien Bachasson,Ericky C. A. Araujo,Lucas Soustelle,Paulo Loureiro de Sousa,Yves Fromes,Pierre G. Carlier +6 more
TL;DR: In this paper, a mouse model with variable levels of induced skeletal muscle fibrosis displaying minimal inflammation and no fat infiltration was described, and how fibrosis affects non-invasive metrics derived from nuclear magnetic resonance (NMR) and ultrasound shear-wave elastography (SWE) associated with a passive biomechanical assay.
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On the local identifiability of constituent stress–strain laws for hyperelastic composite materials
TL;DR: In this article, the authors examined macroscopic samples whose constituent architecture is accessible and investigated whether it is possible to conclude on the stress-strain behavior of individual constituents based on experimental measurements from standard material tests.
References
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Matrix elasticity directs stem cell lineage specification.
TL;DR: Naive mesenchymal stem cells are shown here to specify lineage and commit to phenotypes with extreme sensitivity to tissue-level elasticity, consistent with the elasticity-insensitive commitment of differentiated cell types.
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Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture
Penney M. Gilbert,Karen Havenstrite,Klas E. G. Magnusson,Klas E. G. Magnusson,Alessandra Sacco,Nora Leonardi,Nora Leonardi,Peggy E. Kraft,N. K. Nguyen,Sebastian Thrun,Matthias P. Lutolf,Helen M. Blau +11 more
TL;DR: Using a bioengineered substrate to recapitulate key biophysical and biochemical niche features in conjunction with a highly automated single-cell tracking algorithm, it is shown that substrate elasticity is a potent regulator of MuSC fate in culture.
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Matrix elasticity directs stem cell lineage — Soluble factors that limit osteogenesis
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Cell surface receptors for extracellular matrix molecules
Clayton A. Buck,Alan F. Horwitz +1 more
TL;DR: Avian integrin shows little specificity and appears to behave as a multifunctional, promiscuous receptor for extracellular matrix molecules, and post-translational modifications provide yet another mechanism for regulating integrin-ligand binding.
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Passive tension in cardiac muscle: contribution of collagen, titin, microtubules, and intermediate filaments.
Henk Granzier,Thomas C. Irving +1 more
TL;DR: The passive tension-sarcomere length relation of rat cardiac muscle was investigated by studying passive (or not activated) single myocytes and trabeculae and the contribution of collagen, titin, microtubules, and intermediate filaments to tension and stiffness was investigated.