Journal ArticleDOI
Endobronchial ultrasound-guided transbronchial needle aspiration of lymph nodes in the radiologically and positron emission tomography-normal mediastinum in patients with lung cancer.
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TLDR
EBUS-TBNA can be used to accurately sample and stage patients with clinical stage 1 lung cancer and no evidence of mediastinal involvement on CT and PET and the negative predictive value was 98.9%.About:
This article is published in Chest.The article was published on 2008-04-01. It has received 353 citations till now. The article focuses on the topics: Mediastinal lymphadenopathy & Mediastinum.read more
Citations
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Journal ArticleDOI
Methods for Staging Non-small Cell Lung Cancer: Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
Gerard A. Silvestri,Anne V. Gonzalez,Michael A. Jantz,Mitchell L. Margolis,Michael K. Gould,Lynn T. Tanoue,Loren J. Harris,Frank C. Detterbeck +7 more
TL;DR: It is demonstrated that PET scanning is more accurate than CT scanning, but tissue biopsy is still required to confirm PET scan findings, and evidence suggests that more complete staging improves patient outcomes.
Journal ArticleDOI
Management of non-small-cell lung cancer: recent developments.
TL;DR: The evolution of lung cancer staging towards more non-invasive, endoscopy-based, and image-based methods, and the development of stage-adapted treatment is discussed, with an emphasis on targeted therapies based on the assumption that a treatable driver mutation or gene rearrangement is present within the tumour.
Journal ArticleDOI
Revised ESTS guidelines for preoperative mediastinal lymph node staging for non-small-cell lung cancer.
Paul De Leyn,Christophe Dooms,Jarosław Kużdżał,Didier Lardinois,Bernward Passlick,Ramón Rami-Porta,Akif Turna,Paul Van Schil,Frederico Venuta,David A. Waller,Walter Weder,Marcin Zieliński +11 more
TL;DR: A revision of the ESTS guidelines was needed because more evidence of the different mediastinal staging technique has become available and both endoscopic techniques and surgical procedures are available, but their negative predictive value is lower compared with the results obtained in baseline staging.
Journal ArticleDOI
Endobronchial ultrasound-guided transbronchial needle aspiration for staging of lung cancer: A systematic review and meta-analysis
TL;DR: EBUS-TBNA was an accurate, safe and cost-effective tool in lung cancer staging and the selection of patients who had positive results of suspected lymph node metastasis in CT or PET may improve the sensitivity of EBUS- TBNA.
Journal ArticleDOI
Mediastinoscopy vs Endosonography for Mediastinal Nodal Staging of Lung Cancer: A Randomized Trial
Jouke T. Annema,Jan P. van Meerbeeck,Robert C. Rintoul,Christophe Dooms,Ellen Deschepper,Olaf M. Dekkers,Paul De Leyn,Jerry Braun,Nicholas Carroll,Marleen Praet,Frederick de Ryck,Johan Vansteenkiste,Frank Vermassen,Michel I.M. Versteegh,Maud Veselic,Andrew G. Nicholson,Klaus F. Rabe,Kurt G. Tournoy +17 more
TL;DR: Among patients with (suspected) NSCLC, a staging strategy combining endosonography and surgical staging compared with surgical staging alone resulted in greater sensitivity for mediastinal nodal metastases and fewer unnecessary thoracotomies.
References
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Journal ArticleDOI
Multidisciplinary management of lung cancer.
TL;DR: This review considers the treatment of each type of lung cancer in the framework of multidisciplinary management and recent clinical trials for the more aggressive small-cell lung cancer.
Journal ArticleDOI
Noninvasive Staging of Non-small Cell Lung Cancer*: A Review of the Current Evidence
TL;DR: PET scanning is more accurate than CT scanning or EUS for detecting mediastinal metastases and the NPVs of the clinical evaluations for brain, abdominal, and bone metastases are > or = 90%, suggesting that routinely imaging asymptomatic lung cancer patients may not be necessary.
Journal ArticleDOI
Invasive mediastinal staging of lung cancer: ACCP evidence-based clinical practice guidelines (2nd edition).
Frank C. Detterbeck,Michael A. Jantz,Michael B. Wallace,Johan Vansteenkiste,Gerard A. Silvestri +4 more
TL;DR: In patients with extensive mediastinal infiltration, invasive staging is not needed and patients with a peripheral clinical stage I NSCLC do not usually need invasive confirmation of mediastsinal nodes unless a PET scan finding is positive in the nodes.
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Test performance of positron emission tomography and computed tomography for mediastinal staging in patients with non-small-cell lung cancer: a meta-analysis.
Michael K. Gould,Ware G. Kuschner,Chara E. Rydzak,Courtney C. Maclean,Anita N Demas,Hidenobu Shigemitsu,Jo Kay Chan,Douglas K Owens +7 more
TL;DR: A synthesis of 39 studies found that FDG-PET was more accurate than CT for identifying lymph node involvement and CT was more sensitive but less specific in patients with lymph node enlargement on CT.
Journal ArticleDOI
Noninvasive Staging of Non-small Cell Lung Cancer: ACCP Evidenced-Based Clinical Practice Guidelines (2nd Edition)
Gerard A. Silvestri,Michael K. Gould,Mitchell L. Margolis,Lynn T. Tanoue,Douglas C McCrory,Eric M. Toloza,Frank C. Detterbeck +6 more
TL;DR: In this paper, the authors show that PET scanning is more accurate than CT scanning for detecting mediastinal lymph node metastasis than chest CT scanning, with a pooled sensitivity and specificity of 51% (95% confidence interval [CI], 47 to 54%) and 85%(95% CI, 84 to 88%), respectively.