Endogenous Superoxide Dismutase Levels Regulate Iron-Dependent Hydroxyl Radical Formation in Escherichia coli Exposed to Hydrogen Peroxide
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21,528 citations
"Endogenous Superoxide Dismutase Lev..." refers background in this paper
...rapidly reacts with itself (dismutes) to form H2O2 (7)....
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...Although the aerobic metabolism of bacteria optimally results in the near simultaneous four-electron reduction of O2 to H2O, a variable percentage of O2 reduction occurs initially via either one-electron reduction of O2 to superoxide (O2 ) or divalent reduction to H2O2 (7)....
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1,997 citations
"Endogenous Superoxide Dismutase Lev..." refers background in this paper
...Pretreatment of the JI132 (SOD-deficient) bacteria with DFO greatly reduced the magnitude of OH generation, confirming that it arose as a consequence of Fenton chemistry, as iron bound to DFO is no longer available for this redox chemistry (10)....
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974 citations
"Endogenous Superoxide Dismutase Lev..." refers background in this paper
...Most bacteria, including Escherichia coli, contain superoxide dismutase (SOD) and catalase as means of eliminating O2 z2 and H2O2, respectively (16, 17)....
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851 citations
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