Endogenous Superoxide Dismutase Levels Regulate Iron-Dependent Hydroxyl Radical Formation in Escherichia coli Exposed to Hydrogen Peroxide
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Cites background from "Endogenous Superoxide Dismutase Lev..."
...SOD catalyses the dismutation of SOR to hydrogen peroxide and oxygen (McCormick et al. 1998)....
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...D ow nloaded from https://academ ic.oup.com /pcp/article-abstract/57/9/1899/2223193 by guest on 06 M arch 2019 presence of reduced metal ions, such as Fe2+, which is generated by the reduction of Fe3+ by O2 – (Keyer and Imlay 1996, McCormick et al. 1998)....
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References
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"Endogenous Superoxide Dismutase Lev..." refers background in this paper
...rapidly reacts with itself (dismutes) to form H2O2 (7)....
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...Although the aerobic metabolism of bacteria optimally results in the near simultaneous four-electron reduction of O2 to H2O, a variable percentage of O2 reduction occurs initially via either one-electron reduction of O2 to superoxide (O2 ) or divalent reduction to H2O2 (7)....
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"Endogenous Superoxide Dismutase Lev..." refers background in this paper
...Pretreatment of the JI132 (SOD-deficient) bacteria with DFO greatly reduced the magnitude of OH generation, confirming that it arose as a consequence of Fenton chemistry, as iron bound to DFO is no longer available for this redox chemistry (10)....
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"Endogenous Superoxide Dismutase Lev..." refers background in this paper
...Most bacteria, including Escherichia coli, contain superoxide dismutase (SOD) and catalase as means of eliminating O2 z2 and H2O2, respectively (16, 17)....
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