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Open AccessJournal ArticleDOI

Endometrioid carcinoma of the ovary. A clinicopathologic study of 75 cases

Bernard Czernobilsky, +2 more
- 01 Nov 1970 - 
- Vol. 26, Iss: 5, pp 1141-1152
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TLDR
Survival did not differ significantly between various subgroups or with different modalities of treatment and correlated best with clinical staging, and in 11 patients, there was a concomitant endometrial carcinoma.
Abstract
A clinicopathologic study of 75 endometrioid carcinomas of the ovary was carried out. Thirty‐six of the patients were in clinical Stages I and II and 39 in Stages III and IV. There were 49 histologically “pure” endometrioid carcinomas. the remaining 26 showed histologic admixtures of other neoplasms of Müllerian derivation. Thirty‐six of the 75 cases were adenoacanthomas. By histologic grading, 45 were classified as Grades 1 and 2, 30 as Grades 3 and 4. Thirteen of the ovaries with carcinoma also harbored endometriosis. in 11 patients, there was a concomitant endometrial carcinoma. the 5‐ and 10‐year survival figures for the entire series were 40.5% and 32.7%. Survival did not differ significantly between various subgroups or with different modalities of treatment and correlated best with clinical staging. Five‐year survival was 92.5% in Stage I and 27.8%, 3.7%, and 0% in Stages II, III, and IV.

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Journal ArticleDOI

Origins and molecular pathology of ovarian cancer

TL;DR: It is likely that most low-grade, relatively indolent ovarian carcinomas of serous, mucinous and endometrioid type arise from pre-existing cystadenomas orendometriosis whereas most high-grade serous carcinomas arise without an easily identifiable precursor lesion.
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Figo stage, histology, histologic grade, age and race as prognostic factors in determining survival for cancers of the female gynecological system: An analysis of 1973‐87 SEER cases of cancers of the endometrium, cervix, ovary, vulva, and vagina

TL;DR: Analysis of the prognostic impact of FIGO stage, histology, histologic grade, age and race in survival for cancers of the female gynecological were examined and the interaction of factors may be more predictive of outcome than any one factor separately.
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Endometriosis and the development of malignant tumours of the pelvis. A review of literature

TL;DR: Molecular studies have detected common alterations in endometriosis and ovarian cancer, which suggest that some tumours, especiallyendometrioid and clear-cell carcinomas, can arise from endometRIosis.
Journal ArticleDOI

Metastatic and independent cancers of the endometrium and ovary: A clinicopathologic study of 34 cases

TL;DR: Cancers classified as metastatic, with no known spread outside the endometrium-myometrium and ovary, were found to involve other sites significantly more frequently than those classified as independent, supporting the belief that theendometrium is a primary site in both groups.
Journal ArticleDOI

Simultaneous presentation of carcinoma involving the ovary and the uterine corpus

TL;DR: The excellent survival of patients with simultaneous ovarian and uterine endometrioid carcinomas is better than would be expected for either Stage III adenocarcinoma of the endometrium or Stage II ovarian carcinoma.
References
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Journal ArticleDOI

Endometrial carcinoma of the ovary, arising in endometrial tissue in that organ

TL;DR: Many interesting and important problems have presented themselves to clinicians and pathologists, who have appreciated the frequency of ectopic endometrium-like tissue in the pelvis and have had an opportunity to observe the various lesions in the ovaries and other pelvic structures resulting from this tissue.
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“Mesonephroma” of ovary. Tumor of müllerian nature related to the endometrioid carcinoma

TL;DR: The authors believe that ovarian tumors are müllerian, not mesonephric, and that they are closely related to endometrioid tumors, which have possible therapeutic implications, inasmuch as carcinomas of the uterine endometrium may respond to progestational drugs.
Journal ArticleDOI

The development of malignancy in endometriosis.

TL;DR: The aim of this work was to demonstrate the efforts towards in-situ applicability of EMT in the context of women’s sexual development and Obstetrics and Gynecology.
Journal ArticleDOI

Endometrioid carcinoma of the ovary

TL;DR: Certain morphological and biological characteristics seem to support the contention that this is a distinct type of ovarian tumor, and the possibilities that this tumor is derived from benign endometriosis and that in contrast to other malignant tumors of the ovary it provides a relatively favorable prognosis are pointed out.
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