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Journal ArticleDOI

Enhanced transmembrane transport of reactive oxygen species by electroporation effect of plasma

08 Aug 2021-Plasma Processes and Polymers (John Wiley & Sons, Ltd)-Vol. 18, Iss: 11, pp 2100054
About: This article is published in Plasma Processes and Polymers.The article was published on 2021-08-08. It has received 3 citations till now. The article focuses on the topics: Electroporation & Reactive oxygen species.
Citations
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Journal ArticleDOI
TL;DR: In this paper , the authors introduced the device structure and physicochemical parameters of the two types of plasma scalpels, namely, a single-electrode Ar discharge device (argon plasma coagulation) and a two-Electrode discharge device in normal saline.
Abstract: The plasma scalpel is an application of gas discharges in electrosurgery. This paper introduces the device structure and physicochemical parameters of the two types of plasma scalpels, namely, a single-electrode Ar discharge device (argon plasma coagulation) and a two-electrode discharge device in normal saline. The diagnostic methods, including the voltage and current characteristics, optical emission spectroscopy, electron spin resonance, and high-speed imaging, are introduced to determine the critical process parameters, such as the plasma power, the gas temperature, the electron density, and the density of active species, and study the ignition dynamics of the plasma discharges in water. The efficacy of the plasma scalpel is mainly based on the physical effects of the electric current and electric field, in addition to the chemical effects of high-density energetic electrons and reactive species. These two effects can be adjusted separately to increase the treatment efficacy of the plasma scalpel. Specific guidance on further improvements of the plasma scalpel devices is also provided.
References
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Journal ArticleDOI
TL;DR: To test this hypothesis, peak-to-peak headgroup thicknesses h(pp) of bilayers were obtained from x-ray diffraction of multibilayer arrays at controlled relative humidities and showed that poly-cis unsaturated chain bilayers are thinner and more flexible than saturated/monounsaturated chain Bilayers.

1,725 citations

Journal ArticleDOI
TL;DR: This review of the essential features of theoretical models of electroporation focuses on transient aqueous pore models, which can account for key features of mechanical instability and dramatic reversible electrical behavior of certain planar membranes and of cell membranes, and some features of molecular transport.

1,539 citations

Journal ArticleDOI
TL;DR: Low temperature, high pressure, non-equilibrium plAsmas are now routinely used in several material processing applications, and in some cases are competing with low pressure plasmas in areas where these have historically been dominant.
Abstract: Summary: Low temperature, high pressure, non-equilibrium plasmas are now routinely used in several material processing applications, and in some cases are competing with low pressure plasmas in areas where these have historically been dominant. Etching and deposition are examples of such applications. Amongst the novel applications of non-equilibrium plasmas, biomedical applications such as electrosurgery, surface modification of biocompatible materials, and the sterilization of heat-sensitive medical tools are particularly interesting. In this paper, first a brief overview of recent research on reduced-pressure plasma-based sterilization/decontamination methods is given. Then a detailed review and discussion on the effects of atmospheric pressure non-equilibrium plasmas on the cells of bacteria is presented. This includes the evaluation of the inactivation kinetics and the roles of the various plasma agents in the inactivation process. Measurements of the plasma temperature, the UV emission, and concentrations of various reactive species for the case of air plasma are presented. Plasma sub-lethal effects are also briefly discussed, and the prospects of the use of “cold” plasmas in the biomedical field are outlined.

992 citations

Journal ArticleDOI
TL;DR: In this paper, the most important mechanisms of generation and transport of the key species in the plasmas of atmospheric-pressure plasma jets and other non-equilibrium atmospheric pressure plasms are introduced and examined from the viewpoint of their applications in plasma hygiene and medicine and other relevant fields.

825 citations

Journal ArticleDOI
TL;DR: In this article, the authors used a Coulter Counter with a hydrodynamic focusing orifice to measure the dielectric breakdown of human and bovine red blood cells in a homogeneous electric field between two flat platinum electrodes.

756 citations