Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P 1 antagonist in vivo
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"Enhancement of capillary leakage an..." refers background in this paper
...and abnormalities in the development of the immune syste...
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2,008 citations
"Enhancement of capillary leakage an..." refers background in this paper
...We have characterized selective, reversible chemical tools that acutely alter the set point of S1P-S1P 1 rheostat...
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1,641 citations
"Enhancement of capillary leakage an..." refers background in this paper
...Reverse pharmacology using compounds of unknown molecular interaction that induce disappearance of lymphocytes from the blood and that proved to be S1P receptor agonists first identified the S1P 1 receptor as a target capable of inducing clinically useful immunosuppressio...
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1,159 citations
"Enhancement of capillary leakage an..." refers background in this paper
...Genetic deletions of S1P 1 have revealed the receptor's essential endothelial functions in arterial smooth muscle cell migration; absence of S1P 1 results in embryonic lethalit...
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1,046 citations