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Epidemiology and risk factors of urothelial bladder cancer

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TLDR
UBC is a frequently occurring malignancy with a significant impact on public health and will remain so because of the high prevalence of smoking and the importance of primary prevention must be stressed and smoking cessation programs need to be encouraged and supported.
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This article is published in European Urology.The article was published on 2013-02-01. It has received 1601 citations till now. The article focuses on the topics: Risk factor & Environmental pollution.

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Bladder Cancer Incidence and Mortality: A Global Overview and Recent Trends

TL;DR: The observed patterns and trends of bladder cancer incidence worldwide appear to reflect the prevalence of tobacco smoking, although infection with Schistosoma haematobium and other risk factors are major causes in selected populations.
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Diagnosis and Treatment of Non-Muscle Invasive Bladder Cancer: AUA/SUO Guideline

TL;DR: The intensity and scope of care for NMIBC should focus on patient, disease, and treatment response characteristics, and a risk-stratified approach categorizes patients into broad groups of low-, intermediate-, and high-risk.
References
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Journal ArticleDOI

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008.

TL;DR: The results for 20 world regions are presented, summarizing the global patterns for the eight most common cancers, and striking differences in the patterns of cancer from region to region are observed.
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Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults.

TL;DR: Current patterns of overweight and obesity in the United States could account for 14 percent of all deaths from cancer in men and 20 percent of those in women, and increased body weight was associated with increased death rates for all cancers combined and for cancers at multiple specific sites.
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The present and future burden of urinary bladder cancer in the world

TL;DR: The burden of UBC will increase in less developed areas of the world, and changes can be attributed to global changes in exposure to risk factors for UBC and growth and aging of the World population.
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Association between smoking and risk of bladder cancer among men and women

TL;DR: Compared with a pooled estimate of US data from cohorts initiated between 1963 and 1987, relative risks for smoking in the more recent NIH-AARP Diet and Health Study cohort were higher, with PARs for women comparable with those for men.
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Treatment of muscle-invasive and metastatic bladder cancer: Update of the EAU guidelines

TL;DR: Current data demonstrate that neoadjuvant chemotherapy in conjunction with radical cystectomy (RC) is recommended in certain constellations of MiM-BC, and a new drug for second-line chemotherapy (vinflunine) in metastatic disease has been approved and is recommended.
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