Journal ArticleDOI
Epigenetic codes in cognition and behaviour.
Reads0
Chats0
TLDR
Recent findings on the role and mechanisms of epigenetic codes in the brain are described, and their implication in synaptic plasticity, cognitive functions and psychiatric disorders are discussed.About:
This article is published in Behavioural Brain Research.The article was published on 2008-09-01. It has received 260 citations till now. The article focuses on the topics: Epigenetic code & Epigenetics.read more
Citations
More filters
Dissertation
Investigating the molecular substrates of goal-directed and habitual behaviour
TL;DR: Evidence is demonstrated consistent with a training-induced shift from goal-directed to habitual instrumental behaviour and the role of epigenetic mechanisms, speci�cally histone acetylation, in the regulation of instrumental behaviour by using the histone deacetylase inhibitor sodium butyrate (NaB) to interfere with endogenous chromatin remodelling processes.
Journal ArticleDOI
Epigenetics and the power of art
Heidrun Karlic,Pia Baurek +1 more
TL;DR: An epigenetic view on complex factors leading to development and perception of “genius” is presented, which indicates that artistic creativity is influenced by epigenetic processes that act both as targets and mediators of neurotransmitters as well as steroid hormones.
Journal ArticleDOI
The impact of generative linguistics on psychology: Language acquisition, a paradigm example
Caterina Marino,Judit Gervain +1 more
TL;DR: In the early 1970s, Noam Chomsky's early work was at the core of the "cognitive revolution" in the 1950s-60s, leading to a paradigm shift from a behavioralist to a mentalistic approach to human psychology.
Dissertation
Information Extraction from Text for Improving Research on Small Molecules and Histone Modifications
Journal ArticleDOI
Ginkgo biloba modulates hippocampal BDNF expression in a rat model of chronic restraint stress-induced depression
Seyed Abdolmajid Ayatollahi,shahrokh khoshsirat,Ali Asghar Peyvandi,Omidvar Rezaei,Fatemeh Zare Mehrjardi,Arezo Nahavandi,Somayeh Niknazar +6 more
TL;DR: Findings suggest that Gb can induce an antidepressant role through its modulation effect on the hippocampus of rats subjected to repeated restraint stress, and inhibited chronic stressinduced alterations in the hippocampal BDNF DNA methylation and protein expression.
References
More filters
Journal ArticleDOI
A synaptic model of memory: long-term potentiation in the hippocampus
TL;DR: The best understood form of long-term potentiation is induced by the activation of the N-methyl-d-aspartate receptor complex, which allows electrical events at the postsynaptic membrane to be transduced into chemical signals which, in turn, are thought to activate both pre- and post Synaptic mechanisms to generate a persistent increase in synaptic strength.
Journal ArticleDOI
Chromatin Modifications and Their Function
TL;DR: The surface of nucleosomes is studded with a multiplicity of modifications that can dictate the higher-order chromatin structure in which DNA is packaged and can orchestrate the ordered recruitment of enzyme complexes to manipulate DNA.
Journal ArticleDOI
Translating the Histone Code
Thomas Jenuwein,C. David Allis +1 more
TL;DR: It is proposed that this epigenetic marking system represents a fundamental regulatory mechanism that has an impact on most, if not all, chromatin-templated processes, with far-reaching consequences for cell fate decisions and both normal and pathological development.
Journal ArticleDOI
DNA methylation patterns and epigenetic memory
TL;DR: The heritability of methylation states and the secondary nature of the decision to invite or exclude methylation support the idea that DNA methylation is adapted for a specific cellular memory function in development.
Journal ArticleDOI
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
Rudolf Jaenisch,Adrian Bird +1 more
TL;DR: Advances in the understanding of the mechanism and role of DNA methylation in biological processes are reviewed, showing that epigenetic mechanisms seem to allow an organism to respond to the environment through changes in gene expression.