Journal ArticleDOI
Epigenetic codes in cognition and behaviour.
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TLDR
Recent findings on the role and mechanisms of epigenetic codes in the brain are described, and their implication in synaptic plasticity, cognitive functions and psychiatric disorders are discussed.About:
This article is published in Behavioural Brain Research.The article was published on 2008-09-01. It has received 260 citations till now. The article focuses on the topics: Epigenetic code & Epigenetics.read more
Citations
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Examining Hippocampal Reelin Expression and Neural Plasticity in an Animal Model of Depression
TL;DR: Using nanofiltration membranes for recovery of phosphorous with a second type of technology for the recovery of nitrogen is suggest to be a viable process.
Journal ArticleDOI
Effects of Maternal High-Fructose Diet on Long Non-Coding RNAs and Anxiety-like Behaviors in Offspring
TL;DR: In this article , a maternal high-fructose diet during gestation and lactation could affect nervous system development in offspring, and the mechanism whereby maternal highfructose diets influence offspring brain development by affecting lncRNAs is still unclear.
Dissertation
Impact des obstacles aquatiques sur la migration des jeunes stades d’Anguilla anguilla
TL;DR: L’anguille europeenne Anguilla anguilla est une espece catadrome avec un cycle of vie complexe incluant des migrations entre la mer de Sargasses et l’Europe and l‘Afrique du Nord, on la considere aujourd’hui comme ‘en danger critique’.
Review Article Epigenetic Studies in Human Diseases
TL;DR: The studies of epigenetic dysregulations in cancer as well as the studies of methylation changes and aberrant histone modifications in neurodegenerative, autoimmune, cardiovascular and other diseases are reviewed.
References
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Journal ArticleDOI
A synaptic model of memory: long-term potentiation in the hippocampus
TL;DR: The best understood form of long-term potentiation is induced by the activation of the N-methyl-d-aspartate receptor complex, which allows electrical events at the postsynaptic membrane to be transduced into chemical signals which, in turn, are thought to activate both pre- and post Synaptic mechanisms to generate a persistent increase in synaptic strength.
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Chromatin Modifications and Their Function
TL;DR: The surface of nucleosomes is studded with a multiplicity of modifications that can dictate the higher-order chromatin structure in which DNA is packaged and can orchestrate the ordered recruitment of enzyme complexes to manipulate DNA.
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Translating the Histone Code
Thomas Jenuwein,C. David Allis +1 more
TL;DR: It is proposed that this epigenetic marking system represents a fundamental regulatory mechanism that has an impact on most, if not all, chromatin-templated processes, with far-reaching consequences for cell fate decisions and both normal and pathological development.
Journal ArticleDOI
DNA methylation patterns and epigenetic memory
TL;DR: The heritability of methylation states and the secondary nature of the decision to invite or exclude methylation support the idea that DNA methylation is adapted for a specific cellular memory function in development.
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Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
Rudolf Jaenisch,Adrian Bird +1 more
TL;DR: Advances in the understanding of the mechanism and role of DNA methylation in biological processes are reviewed, showing that epigenetic mechanisms seem to allow an organism to respond to the environment through changes in gene expression.