Estimates of the cancer incidence and mortality in Europe in 2006
TL;DR: The total number of new cases of cancer in Europe appears to have increased by 300,000 since 2004 and the ageing of the European population will cause these numbers to continue to increase even if age-specific rates remain constant.
About: This article is published in Annals of Oncology.The article was published on 2006-11-02 and is currently open access. It has received 4155 citations till now. The article focuses on the topics: Cancer & Breast cancer.
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TL;DR: The results for 20 world regions are presented, summarizing the global patterns for the eight most common cancers, and striking differences in the patterns of cancer from region to region are observed.
Abstract: Estimates of the worldwide incidence and mortality from 27 cancers in 2008 have been prepared for 182 countries as part of the GLOBOCAN series published by the International Agency for Research on Cancer. In this article, we present the results for 20 world regions, summarizing the global patterns for the eight most common cancers. Overall, an estimated 12.7 million new cancer cases and 7.6 million cancer deaths occur in 2008, with 56% of new cancer cases and 63% of the cancer deaths occurring in the less developed regions of the world. The most commonly diagnosed cancers worldwide are lung (1.61 million, 12.7% of the total), breast (1.38 million, 10.9%) and colorectal cancers (1.23 million, 9.7%). The most common causes of cancer death are lung cancer (1.38 million, 18.2% of the total), stomach cancer (738,000 deaths, 9.7%) and liver cancer (696,000 deaths, 9.2%). Cancer is neither rare anywhere in the world, nor mainly confined to high-resource countries. Striking differences in the patterns of cancer from region to region are observed.
21,040 citations
TL;DR: Up-to-date estimates of the cancer burden in Europe alongside the description of the varying distribution of common cancers at both the regional and country level provide a basis for establishing priorities to cancer control actions in Europe.
4,722 citations
Umeå University1, University of Rennes2, University of Texas at Austin3, Charles University in Prague4, Hanover College5, University of Aberdeen6, University of Coimbra7, Radboud University Nijmegen8, St Bartholomew's Hospital9, Ludwig Maximilian University of Munich10, University of Eastern Piedmont11, Netherlands Cancer Institute12
TL;DR: The 2014 RCC guideline has been updated by a multidisciplinary panel using the highest methodological standards, and provides the best and most reliable contemporary evidence base for RCC management.
3,100 citations
TL;DR: The statistical models used used to estimate incidence and mortality data for 25 cancers in 40 European countries in 2008 used to obtain an estimate of the numbers of cancer cases and deaths in Europe in 2008.
2,358 citations
TL;DR: In this article, the authors investigated the combination treatment of the humanised anti-VEGF monoclonal antibody bevacizumab with interferon alfa, and reported a significant improvement in progression-free survival.
2,167 citations
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National Institutes of Health1, Saint Louis University2, University of California, Berkeley3, United States Environmental Protection Agency4, University of Oxford5, Louisiana State University6, Fudan University7, Tata Institute of Fundamental Research8, Queen Mary University of London9, University of Minnesota10, Finnish Institute of Occupational Health11, University of Buenos Aires12, Johns Hopkins University13, Ohio State University14, American Cancer Society15, University of Paris16, University of Turin17, University of Southern California18, Russian Academy19
1,761 citations
TL;DR: Estimates of the cancer burden in Europe in 2004 are presented, including data for the (25 Member States) European Union, to make a concerted attack on the big killers: lung, colorectal, breast and stomach cancer.
1,272 citations
TL;DR: On peut constater qu'il existe au sein of l'Europe un intervalle de variation des taux nettement plus large que dans les autres régions développées du monde.
Abstract: Cet ouvrage de reference, essentiellement descriptif, presente sous une forme principalement graphique, accompagnee de tres brefs commentaires, les elements suivants: 1. les taux d'incidence, standardis es par rapport a la population mondiale, pour 31 localisations ou groupes de localisations cancereuses de 45 regions appartenant a 19 pays europeens qui figurent dans le volume 5 de la serie «Cancer Incidence in Five Continents»; 2. les donnees officielles de mortalite fournies par l'Organisation mondiale de la Sante pour 27 localisations et 26 pays pour la periode correspondant a l'incidence, comprise entre 1978 et 1982. Le supplement fournit egalement les rapports homme/femme d'incidence et de mortalite pour chaque pays et region d'Europe consideres, ainsi que le rang de chaque localisation ou pays/region, respectivement au sein de chaque pays/region ou localisation. Parmi les constatations les plus importantes de ce rapport on relevera:
les taux eleves d'incidence et de mortalite par cancer pulmonaire en Ecosse dans les deux sexes et en Angleterre, les plus bas etant enregistres en Scandinavie, Espagne et Italie du Sud;
les niveaux eleves des neoplasies liees a l'exposition conjointe au tabac et a l'alcool en France, en Suisse romande, en Italie du Nord et en Ecosse, surtout chez la femme;
les taux generalement faibles dans les populations mediterraneennes (Espagne, Italie du Sud et Grece) pour la plupart des autres tumeurs frequentes, notamment de l'estomac, du colorectum et du sein;
les rangs particulierement eleves des cancers genitaux en Scandinavie, en Suisse et en Italie du Nord, de l'incidence des tumeurs de la vessie dans les regions a haute concentration d'industries chimiques, des tumeurs thyroidiennes en Scandinavie et en Suisse, et des tumeurs lymphatiques en Ecosse, en Suisse et en Italie du Nord.
1,263 citations
TL;DR: Cancer incidence and mortality estimates for 1995 are presented for the 38 countries in the four United Nations-defined areas of Europe, using World Health Organization mortality data and published estimates of incidence from national cancer registries to demonstrate the very substantial burden of cancer in Europe, and the scope for prevention.
1,216 citations