Estimating Sensitivity and Sojourn Time in Screening for Colorectal Cancer A Comparison of Statistical Approaches
Cites background or methods or result from "Estimating Sensitivity and Sojourn ..."
...To make the results comparable with estimates provided in previous studies [5,12-15], all cases of ductal carcinoma in situ (DCIS) – a noninvasive form of breast tumor – were included....
...time unit (month) without screening – to simplify calculations, the rate is assumed constant over time as in the earlier used Markov model [5,12], probably giving a good approximation in the limited time span used in the estimation – and , i f gs , is the probability that a clinical...
...Overall, sensitivity investigations indicate that the new model is probably less vulnerable to several potential biases than the Markov model [5,12], possibly as a result of more utilized data....
...Generally, this model combines many of the advantages of the large population-based Markov methods [5,12], with more specific tumor growth estimates found in clinical studies of overlooked cancers....
...These studies  are usually analyzed using Markov models [5,6], where the mean time for a breast cancer tumor to growth from screening-detectable size to clinical detection without screening – the so-called mean sojourn time – and the STS are estimated....
Cites methods from "Estimating Sensitivity and Sojourn ..."
...This study was aimed at accurately estimating the lead time affecting semiannual and annual surveillance for HCC through a rigorous mathematical model already proposed in other cancer screening programs [15-16]....
...This distribution was used to calculate the transition rate to symptomatic disease and lead time, using the appropriate formula (equation 4) [15,16,19]....