Ethyl 2-[5-(4-chloro-phen-yl)-1-(4-fluoro-phen-yl)-1H-pyrazol-3-yl]-4-methyl-thia-zole-5-carboxyl-ate.
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TLDR
In the title compound, C22H17ClFN3O2S, the pyrazole ring is approximately planar with a maximum deviation of 0.001 (4) Å and makes dihedral angles of 4.95‹(19)‹° with the thiazole, fluorobenzene and chlorobenzenes rings, respectively.Abstract:
In the title compound, C22H17ClFN3O2S, the pyrazole ring is approximately planar with a maximum deviation of 0.001 (4) A and makes dihedral angles of 4.95 (19), 35.78 (18) and 54.73 (18)° with the thiazole, fluorobenzene and chlorobenzene rings, respectively. In the crystal, intermolecular C—H⋯O hydrogen bonds link the molecules into chains along the a axis.read more
Citations
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4-Methyl-5-phenyl-1H-pyrazol-3(2H)-one.
TL;DR: The asymmetric unit of the title compound, C10H10N2O, contains two crystallographically independent molecules with similar geometries, which exist in the keto form, indicating that the compound undergoes enol-to-keto tautomerism during the crystallization process.
Journal ArticleDOI
5-Isobutyl-4-phenyl-sulfonyl-1H-pyrazol-3(2H)-one.
TL;DR: The title compound, C13H16N2O3S, consists of two crystallographically independent mol-ecules with similar geometries and exists in a keto form, the C=O bond lengths being 1.267
References
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A short history of SHELX
TL;DR: This paper could serve as a general literature citation when one or more of the open-source SH ELX programs (and the Bruker AXS version SHELXTL) are employed in the course of a crystal-structure determination.
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A nitrogen‐gas‐stream cryostat for general X‐ray diffraction studies
J. Cosier,A. M. Glazer +1 more
TL;DR: In this paper, a continuous nitrogen-flow cooling device for X-ray diffraction studies is described, which works in the range 77.4 to 323.0 k with a precision of ± 0.1 k and a liquid-nitrogen constant consumption rate of 0.5 k−1 over the whole temperature range.
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Synthesis and antimicrobial activities of novel 1,5-diaryl pyrazoles.
TL;DR: Interestingly all the synthesized compounds exhibited good antibacterial and antifungal activity (except 2a-c, 6a, 8, 9a).
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Synthesis of some novel bioactive 4-oxy/thio substituted-1H-pyrazol-5(4H)-ones via efficient cross-Claisen condensation
TL;DR: alpha-Oxy/thio substituted-beta-keto esters were synthesized through an efficient cross-Claisen condensation of aryl oxy/thIO acetic acid ethyl esters with acid chlorides and screened for their antibacterial, antifungal activities.