Evaluation of the Antibacterial Activity of 14 Medicinal Plants in Côte d’Ivoire
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TLDR
The findings provide support for the use of these plants in traditional medicine for treatment of typhoid fever and gastrointestinal disorders, and are thus, potential sources of drugs that would need to be subjected to further studies.Abstract:
Purpose: To evaluate the antibacterial potentials of fourteen ethnobotanically selected plants traditionally used in different parts of Cote d’Ivoire for the treatment of typhoid fever and gastrointestinal disorders. Method: The antimicrobial activity of the extracts of the plant was tested against a collection strain of Salmonella typhimurium, a clinical strain of Salmonella typhi and Pseudomonas aeruginosa by macrobroth dilution method. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined. Results: All the plants had bactericidal activity against at least one of the test microorganisms with both MIC and MBC ranging from 2.5 to > 80 mg/ml. Among the plant extracts, Terminalia glaucescens . (Combretaceae) Bersama abyssinica subsp. paullinioides (Melianthaceae ) and Abrus precatorius (Fabaceae) showed the most promising broad spectrum antibacterial properties, inhibiting all of the strains tested, especially S. Typhi and P. aeruginosa , with MBC ranging from 2.5 to 5 mg/ml. Conclusion: The findings provide support for the use of these plants in traditional medicine for treatment of typhoid fever and gastrointestinal disorders, and are thus, potential sources of drugs that would need to be subjected to further studies. Keywords: Antimicrobial activity, Ivorian medicinal plants, MIC, MBC.read more
Citations
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Antimicrobial Activities of Vernonia amygdalina Del and Prunus africana Extracts against Multidrug Resistant Clinical Strains
Fanta Gashe,Gemechu Zeleke +1 more
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Chemistry and pharmacology of three antiplasmodial traditional medicinal plants from tropical Africa – A review
TL;DR: An extensive investigation is needed to exploit other therapeutic utilities and validate other ethnobotanical uses of these species, including S. tragacantha, Z. gilletii, and A. polycarpa.
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The traditional uses, phytochemistry and pharmacology of Abrus precatorius L.: A comprehensive review.
TL;DR: Abrus precatorius L. as mentioned in this paper is a folk medicine with a long-term medicinal history worldwide, which is extensively applied to various ailments, such as bronchitis, jaundice, hepatitis, contraception, tumor, abortion, malaria, etc.
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Antipyretic Potential of 80% Methanol Extract and Solvent Fractions of Bersama abyssinica Fresen. (Melianthaceae) Leaves Against Yeast-Induced Pyrexia in Mice
TL;DR: In this paper , the antipyretic potential of B. abyssinica leaves was evaluated using a yeast-induced pyrexia model at three different dose ranges (100mg/kg, 200mg/ kg, and 400 mg/kg) methanol extract as well as chloroform, ethyl acetate, and aqueous fractions to mice showing an increase in temperature of ≥ 0.5 °C.
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Phytochemical Screening, Antibacterial Activity And Acute Oral Toxicity Of Aqueous And Ethanolic Extracts Of Harrisonia Abyssinica (Rutaceae) Leaf: Wild Plant Used In Benin Pharmacopeia
Ogougbé Raïmantou Egbèyèmi,Atindéhou Ménonvè Cynthia,Ossé Razack,Hounguè Rodrigue,Laleye Anatole,Djego Julien +5 more
TL;DR: Phytochemical screening revealed the presence of gallic tannins, alkaloids, reducing sugar, coumarins, quinones, steroids, terpene and saponosides in H. abyssinica leaves, and no toxicity was observed in rats.
References
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Performance standards for antimicrobial susceptibility testing
TL;DR: The supplemental information presented in this document is intended for use with the antimicrobial susceptibility testing procedures published in the following Clinical and Laboratory Standards Institute (CLSI)–approved standards.
Journal ArticleDOI
Plant Products as Antimicrobial Agents
TL;DR: The current status of botanical screening efforts, as well as in vivo studies of their effectiveness and toxicity, are summarized and the structure and antimicrobial properties of phytochemicals are addressed.
Plant products as antimicrobial agents
Daciana Ciocan,Bara Ioan +1 more
TL;DR: Plants produce a diverse array of secondary metabolites, many of which have antimicrobial activity, which occur as inactive precursors and are activated in response to tissue damage or pathogen attack.