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Journal ArticleDOI

Evanescent wave absorbance based fiber optic biosensor for label-free detection of E. coli at 280 nm wavelength.

TL;DR: It is shown that the enhanced EWA response from such U-bent probes, caused by the inherent optical absorbance properties of bacterial cells or biomolecules specifically bound to the sensor surface, can be exploited for the detection of pathogens.
About: This article is published in Biosensors and Bioelectronics.The article was published on 2011-03-15. It has received 101 citations till now. The article focuses on the topics: Fiber optic sensor & Optical fiber.
Citations
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Journal ArticleDOI
TL;DR: This paper presents a meta-anatomy of the response of the immune system to PNA-Based Biosensors (DNA, Aptamers) and some of the mechanisms leading to cell reprograming and apoptosis.
Abstract: ■ CONTENTS Books, Reviews, and Articles of General Interest 488 Sensors for (Dissolved) Gases and Vapors 489 Hydrogen 489 Hydrocarbons 490 Oxygen 491 Ammonia 493 Carbon Dioxide 494 Nitrogen Oxides 494 Vapors of Organic Solvents 495 Sensors for Humidity, Water Fractions, Hydrogen Peroxide, and Hydrazine 495 Humidity 495 Water Fractions 496 Hydrogen Peroxide and Hydrazine 496 Sensors for pH Values, Ions, and Salinity 496 pH Values 496 Ions 497 Salinity and Ionic Strength 499 Sensors for Organic Species 499 Biosensors 500 Immunosensors 500 PNA-Based Biosensors (DNA, Aptamers) 501 Other Affinity Sensors 501 Enzymatic Biosensors 502 Whole Cell Sensors 502 Advanced Optical Sensing Schemes and Materials 503 Author Information 505 Corresponding Author 505 Notes 505 Biographies 505 Acknowledgments 505 References 505

419 citations

Journal ArticleDOI
16 Aug 2017-Sensors
TL;DR: This paper reviews different methodologies to detect pathogens and toxins in foods and beverages and concludes that smart sensors can play a major role, ensuring greater food quality and safety by low cost, fast, reliable, and profitable methods of detection.
Abstract: Pathogen and toxin-contaminated foods and beverages are a major source of illnesses, even death, and have a significant economic impact worldwide. Human health is always under a potential threat, including from biological warfare, due to these dangerous pathogens. The agricultural and food production chain consists of many steps such as harvesting, handling, processing, packaging, storage, distribution, preparation, and consumption. Each step is susceptible to threats of environmental contamination or failure to safeguard the processes. The production process can be controlled in the food and agricultural sector, where smart sensors can play a major role, ensuring greater food quality and safety by low cost, fast, reliable, and profitable methods of detection. Techniques for the detection of pathogens and toxins may vary in cost, size, and specificity, speed of response, sensitivity, and precision. Smart sensors can detect, analyse and quantify at molecular levels contents of different biological origin and ensure quality of foods against spiking with pesticides, fertilizers, dioxin, modified organisms, anti-nutrients, allergens, drugs and so on. This paper reviews different methodologies to detect pathogens and toxins in foods and beverages.

123 citations


Cites background from "Evanescent wave absorbance based fi..."

  • ...coli [72,73], Salmonella [74,75], Listeria [76,77], and others [78,79]....

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  • ...coli [72,73], Salmonella [74,75], Listeria [76,77], and others [78,79]]....

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Journal ArticleDOI
TL;DR: A compact, portable, label-free, and ultra-sensitive sensor is proposed to detect cancerous cells based on Multi-Core Fiber comprising of seven cores arranged in a hexagonal shape spliced with Single-Mode Fiber for efficient detection of different types of cancer cells.

94 citations

Journal ArticleDOI
TL;DR: In this paper, a chemical sensor utilizing localized surface plasmon resonance (LSPR) of gold nanoparticles (GNP) for vapour phase detection of explosives like 2,4,6-trinitrotoluene (TNT) and cyclotrimethylenetrinitramine (RDX).
Abstract: In this study, we report a chemical sensor utilizing localized surface plasmon resonance (LSPR) of gold nanoparticles (GNP) for vapour phase detection of explosives like 2,4,6-trinitrotoluene (TNT) and cyclotrimethylenetrinitramine (RDX). The GNP were immobilized on a U-bend fibre optic sensor probe of 200 μm core diameter and bend diameter of 1.5 mm for evanescent field based excitation of localized surface plasmons of the GNP. The immobilized GNP were functionalized with receptor molecules viz. 4-mercaptobenzoic acid (4-MBA), l -cysteine and cysteamine to provide the binding sites for the nitro-based explosive molecules. Binding of the explosive analytes to the surface moieties of the GNP was found to elicit refractive index changes in the environment surrounding the nanoparticles. This led to changes in the absorbance characteristics of the GNP-LSPR spectrum. Furthermore, the GNP coated probes modified with l -cysteine and cysteamine exhibited a high degree of selectivity towards TNT. The detection limit of the LSPR fibre optic probe for TNT vapours was found to be in the lower parts per billion (ppb) with further scope for improvement.

67 citations

Journal ArticleDOI
TL;DR: It has been shown that the system is capable of providing positive response to the bacterial concentration in less than 10 min, demonstrating good possibilities to be commercially developed as a portable field sensor.

67 citations

References
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Journal ArticleDOI
TL;DR: This work presents a meta-analysis of the literature on food quality and safety analysis and its applications in the context of veterinary drugs and drugs and drug-Induced Antibodies, which focuses on the role of canine coronavirus in the veterinary industry.
Abstract: 5.1. Detection Formats 475 5.2. Food Quality and Safety Analysis 477 5.2.1. Pathogens 477 5.2.2. Toxins 479 5.2.3. Veterinary Drugs 479 5.2.4. Vitamins 480 5.2.5. Hormones 480 5.2.6. Diagnostic Antibodies 480 5.2.7. Allergens 481 5.2.8. Proteins 481 5.2.9. Chemical Contaminants 481 5.3. Medical Diagnostics 481 5.3.1. Cancer Markers 481 5.3.2. Antibodies against Viral Pathogens 482 5.3.3. Drugs and Drug-Induced Antibodies 483 5.3.4. Hormones 483 5.3.5. Allergy Markers 483 5.3.6. Heart Attack Markers 484 5.3.7. Other Molecular Biomarkers 484 5.4. Environmental Monitoring 484 5.4.1. Pesticides 484 5.4.2. 2,4,6-Trinitrotoluene (TNT) 485 5.4.3. Aromatic Hydrocarbons 485 5.4.4. Heavy Metals 485 5.4.5. Phenols 485 5.4.6. Polychlorinated Biphenyls 487 5.4.7. Dioxins 487 5.5. Summary 488 6. Conclusions 489 7. Abbreviations 489 8. Acknowledgment 489 9. References 489

3,698 citations


"Evanescent wave absorbance based fi..." refers background in this paper

  • ...The demonstrated detection limit of these probes is better han or equal to most label-free optical sensors reported hitherto 104 cfu/ml as in Fan et al., 2008; Homola, 2008 to 102 cfu/ml as n Waswa et al., 2006; Oh et al., 2003)....

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Journal ArticleDOI
TL;DR: This article reviews the recent progress in optical biosensors that use the label-free detection protocol, in which biomolecules are unlabeled or unmodified, and are detected in their natural forms, and focuses on the optical biosENSors that utilize the refractive index change as the sensing transduction signal.

2,060 citations


"Evanescent wave absorbance based fi..." refers background in this paper

  • ...The demonstrated detection limit of these probes is better han or equal to most label-free optical sensors reported hitherto 104 cfu/ml as in Fan et al., 2008; Homola, 2008 to 102 cfu/ml as n Waswa et al., 2006; Oh et al., 2003)....

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Journal ArticleDOI
TL;DR: Tapered fiber-optic biosensors (TFOBS) as mentioned in this paper are a type of FOBS which rely on special geometries to expose the evanescent field to interact with samples.
Abstract: Fiber-optic biosensors (FOBS) are optical fiber-derived devices which use optical field to measure biological species such as cells, proteins, and DNA. Because of their efficiency, accuracy, low cost, and convenience, FOBS are promising alternatives to traditional immunological methods for biomolecule measurements. Tapered fiber-optic biosensors (TFOBS) are a type of FOBS which rely on special geometries to expose the evanescent field to interact with samples. In order to amplify sensitivity and selectivity, TFOBS are often used with various optical transduction mechanisms such as changes in refractive index, absorption, fluorescence, and Surface Plasmon Resonance. In this review, the basic principles of TFOBS are summarized. Various common geometries for evanescent sensing and the influence of geometric parameters on optical principles are reviewed. Finally, a detailed account of the studies done to date for biomolecules detection using TFOBS will be provided. © 2007 Elsevier B.V. All rights reserved.

623 citations


"Evanescent wave absorbance based fi..." refers background in this paper

  • ...The evanescent field intensity and/or its penetration depth can be improved by modifying the fiber probe geometry (Leung et al., 2007)....

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Journal ArticleDOI
TL;DR: The quantitative and simultaneous detection of four species of bacteria, Escherichia coli O157:H7, Salmonella choleraesuis serotype typhimurium, Listeria monocytogenes, and Campylobacter jejuni, using an eight-channel surface plasmon resonance (SPR) sensor based on wavelength division multiplexing is reported.

303 citations


"Evanescent wave absorbance based fi..." refers background in this paper

  • ...Several abel-free optical sensing techniques such as, surface plasmon esonance (SPR) (Taylor et al., 2006), grating coupled wavegides (Hórváth et al., 2003), metal clad waveguides (Zourob et al., 005), ring resonator (Ramachandran et al., 2008), photonic crysals (Ouyang et al., 2007), and fiber Bragg’s gratings (DeLisa et al., 000) have been investigated for pathogen detection....

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  • ...Several abel-free optical sensing techniques such as, surface plasmon esonance (SPR) (Taylor et al., 2006), grating coupled wavegides (Hórváth et al., 2003), metal clad waveguides (Zourob et al., 005), ring resonator (Ramachandran et al., 2008), photonic crysals (Ouyang et al., 2007), and fiber…...

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  • ...In addition, these probes re at least an order less sensitive to bulk refractive index changes han SPR based biosensors (Sai et al., 2009) due to higher numerical perture of the probes UV region (Sai et al., 2010)....

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  • ...Recently, we have shown the advantages of U-bent fiber probes over straight fiber probes by developing a sensitive EWA based localized surface plasmon resonance (LSPR) biosensor (Sai et al., 2009)....

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Journal ArticleDOI
TL;DR: A sensor for sensitive measurement of refractive index (RI) with the help of optical absorbance properties of gold nanoparticles (GNP) coupled to an efficient optical transducer in the form of a U-bent fiber optic probe is described.

261 citations


"Evanescent wave absorbance based fi..." refers background or methods in this paper

  • ...Fiber optic probe preparation Fiber optic probes were fabricated as described in our earlier ork (Sai et al., 2009)....

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  • ...Optical setup The optical set-up (Figure S-2 of Supplementary mateial) used for the experiments is similar to our previous tudies (Sai et al., 2009)....

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  • ...In addition, these probes re at least an order less sensitive to bulk refractive index changes han SPR based biosensors (Sai et al., 2009) due to higher numerical perture of the probes UV region (Sai et al., 2010)....

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  • ...Recently, we have shown the advantages of U-bent fiber probes over straight fiber probes by developing a sensitive EWA based localized surface plasmon resonance (LSPR) biosensor (Sai et al., 2009)....

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