Journal ArticleDOI
Exclusion of Kaposi Sarcoma From Analysis of Cancer Burden-Reply.
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This article is published in JAMA Oncology.The article was published on 2017-10-01. It has received 151 citations till now.read more
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Unravelling the biology of SCLC: implications for therapy
Joshua K. Sabari,Benjamin H. Lok,James Laird,John T. Poirier,Charles M. Rudin,Charles M. Rudin +5 more
TL;DR: Progress made in uncovering aspects of the biology of SCLC and its microenvironment that are defining new therapeutic strategies and offering renewed hope for patients are reviewed.
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METTL14 suppresses proliferation and metastasis of colorectal cancer by down-regulating oncogenic long non-coding RNA XIST
Xiao Yang,Sen Zhang,Changyu He,Pei Xue,Luyang Zhang,Zirui He,Lu Zang,Bo Feng,Jing Sun,Minhua Zheng +9 more
TL;DR: Functionally, knockdown of METTL14 drastically enhanced proliferative and invasive ability of CRC cells in vitro and promoted tumorigenicity and metastasis in vivo and extended the understanding of the importance of RNA epigenetics in cancer biology.
Journal ArticleDOI
Making the first move in EGFR-driven or ALK-driven NSCLC: first-generation or next-generation TKI?
Gonzalo Recondo,Francesco Facchinetti,Ken A. Olaussen,Benjamin Besse,Benjamin Besse,Luc Friboulet +5 more
TL;DR: Preclinical and clinical evidence supporting both treatment strategies — the ‘historical’ sequential treatment strategy and the use of next-generation TKIs — as frontline therapies are described and the suitability of both strategies for patients with EGFR-driven or ALK-driven NSCLC is discussed.
Journal ArticleDOI
Mouse models of hepatocellular carcinoma: an overview and highlights for immunotherapy research
TL;DR: An overview of the different mouse models of hepatocellular carcinoma is provided, presenting techniques to prepare an HCC mouse model and discussing different approaches to help researchers choose an appropriate model for a specific hypothesis.
Journal ArticleDOI
Physical activity programming and counseling preferences among cancer survivors: a systematic review.
TL;DR: Cancer survivors have an interest in participating in PA programs with walking as the primary modality, and morning-based PA programs that can be tapered to home-based programs are desirable, however, there was wide variation in other PA preference variables, suggesting multiple program options would be beneficial.
References
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Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980-2015: the Global Burden of Disease Study 2015
Haidong Wang,Timothy M. Wolock,Austin Carter,Grant Nguyen,Hmwe H Kyu,Emmanuela Gakidou,Simon I. Hay,Edward J Mills,Adam Trickey,William Msemburi,Matthew M Coates,Meghan D. Mooney,Maya S Fraser,Amber Sligar,Joshua A. Salomon,Heidi J. Larson,Joseph Friedman,Amanuel Alemu Abajobir,Kalkidan Hassen Abate,Kaja Abbas,Mohamed Magdy Abd El Razek,Foad Abd-Allah,Abdishakur M. Abdulle,Semaw Ferede Abera,Ibrahim Abubakar,Laith J. Abu-Raddad,Niveen M E Abu-Rmeileh,Gebre Yitayih Abyu,Akindele Olupelumi Adebiyi,Isaac Akinkunmi Adedeji,Isaac Akinkunmi Adedeji,Ademola Lukman Adelekan,Koranteng Adofo,Arsène Kouablan Adou,Oluremi N Ajala,Oluremi N Ajala,Tomi Akinyemiju,Nadia Akseer,Faris Lami,Ziyad Al-Aly,Khurshid Alam,Khurshid Alam,Noore Alam,Deena Alasfoor,Saleh F. Aldhahri,Robert W Aldridge,Miguel Angel Alegretti,Alicia Aleman,Zewdie Aderaw Alemu,Rafael Alfonso-Cristancho,Raghib Ali,Ala'a Alkerwi,François Alla,Rajaa Mohammad,Salem Al-Raddadi,Ubai Alsharif,Elena Alvarez,Nelson Alvis-Guzman,Azmeraw T. 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Doyle,Tim Driscoll,Manisha Dubey,Yousef Mohamed Elshrek,Iqbal R. F. Elyazar,Aman Yesuf Endries,Sergey Petrovich Ermakov,Babak Eshrati,Alireza Esteghamati,Imad D A Faghmous,Carla Sofia e Sa Farinha,André Faro,Maryam S. Farvid,Maryam S. Farvid,Farshad Farzadfar,Seyed-Mohammad Fereshtehnejad,João C. Fernandes,Florian Fischer,Joseph R Fitchett,Nataliya Foigt,Nancy Fullman,Thomas Fürst,Fortuné Gbètoho Gankpé,Teshome Gebre,Amanuel Tesfay Gebremedhin,Amanuel Tesfay Gebremedhin,Alemseged Aregay Gebru,Johanna M. Geleijnse,Bradford D. Gessner,Peter W. Gething,Tsegaye Tewelde Ghiwot,Maurice Giroud,Melkamu Dedefo Gishu,Elizabeth Glaser,Shifalika Goenka,Amador Goodridge,Sameer Vali Gopalani,Atsushi Goto,Harish Chander Gugnani,Mark Drew Crosland Guimarães,Rashmi Gupta,Rajeev Gupta,Vipin Gupta,Juanita A. Haagsma,Nima Hafezi-Nejad,Holly Hagan,Gessessew Bugssa Hailu,Randah R. Hamadeh,Samer Hamidi,Mouhanad Hammami,Graeme J. Hankey,Yuantao Hao,Hilda L Harb,Sivadasanpillai Harikrishnan,Josep Maria Haro,Kimani M Harun,Kimani M Harun,Rasmus Havmoeller,Mohammad Taghi Hedayati,Ileana Heredia-Pi,Hans W. Hoek,Masako Horino,Nobuyuki Horita,H. Dean Hosgood,Damian G Hoy,Mohamed Hsairi,Guoqing Hu,Hsiang Huang,John J Huang,Kim Moesgaard Iburg,Bulat Idrisov,Kaire Innos,Veena R. Iyer,Kathryn H. Jacobsen,Nader Jahanmehr,Mihajlo Jakovljevic,Mehdi Javanbakht,Achala Upendra Jayatilleke,Panniyammakal Jeemon,Vivekanand Jha,Guohong Jiang,Ying Jiang,Tariku Jibat,Tariku Jibat,Jost B. Jonas,Zubair Kabir,Ritul Kamal,Haidong Kan,André Karch,Corine Karema,Dimitris Karletsos,Amir Kasaeian,Anil Kaul,Norito Kawakami,Jeanne Françoise Kayibanda,Peter Njenga Keiyoro,Andrew H. Kemp,Andrew H. Kemp,Andre Pascal Kengne,Andre Pascal Kengne,Chandrasekharan Nair Kesavachandran,Yousef Khader,Ibrahim A Khalil,Abdur Rahman Khan,Ejaz Ahmad Khan,Young-Ho Khang,Jagdish Khubchandani,Yun Jin Kim,Yohannes Kinfu,Miia Kivipelto,Yoshihiro Kokubo,Soewarta Kosen,Parvaiz A Koul,Ai Koyanagi,Barthelemy Kuate Defo,Burcu Kucuk Bicer,Veena S. Kulkarni,G Anil Kumar,Dharmesh Kumar Lal,Hilton Lam,Jennifer O Lam,Sinead Langan,Van C. Lansingh,Anders Larsson,James Leigh,Ricky Leung,Yongmei Li,Stephen S Lim,Steven E. Lipshultz,Shiwei Liu,Belinda K Lloyd,Belinda K Lloyd,Giancarlo Logroscino,Paulo A. Lotufo,Raimundas Lunevicius,Raimundas Lunevicius,Hassan Magdy Abd El Razek,Mahdi Mahdavi,Padukudru Anand Mahesh,Marek Majdan,Azeem Majeed,Carla Makhlouf,Reza Malekzadeh,Chabila C Mapoma,Wagner Marcenes,Jose Martinez-Raga,Melvin Barrientos Marzan,Felix Masiye,Amanda J. Mason-Jones,Bongani M. Mayosi,Martin McKee,Peter A. Meaney,Peter A. Meaney,Man Mohan Mehndiratta,Alemayehu B. Mekonnen,Alemayehu B. Mekonnen,Yohannes Adama Melaku,Yohannes Adama Melaku,Peter Memiah,Peter Memiah,Ziad A. Memish,Ziad A. Memish,Walter Mendoza,Atte Meretoja,Atte Meretoja,Tuomo J. Meretoja,Tuomo J. Meretoja,Francis Apolinary Mhimbira,Ted R. Miller,Ted R. Miller,Joseph Mikesell,Mojde Mirarefin,Karzan Abdulmuhsin Mohammad,Shafiu Mohammed,Shafiu Mohammed,Ali H. Mokdad,Lorenzo Monasta,Maziar Moradi-Lakeh,Maziar Moradi-Lakeh,Rintaro Mori,Ulrich O Mueller,Brighton Murimira,Gudlavalleti V S Murthy,Aliya Naheed,Luigi Naldi,Vinay Nangia,Denis Nash,Haseeb Nawaz,Chakib Nejjari,Frida Namnyak Ngalesoni,Jean de Dieu Ngirabega,Quyen Nguyen,Muhammad Imran Nisar,Ole Frithjof Norheim,Rosana E. Norman,Luke Nyakarahuka,Felix Akpojene Ogbo,In-Hwan Oh,Foluke Adetola Ojelabi,Bolajoko O. Olusanya,Jacob Olusegun Olusanya,John Nelson Opio,Eyal Oren,Erika Ota,Hye-Youn Park,Jae-Hyun Park,Snehal Patil,Scott B. Patten,Vinod K. Paul,Katherine Pearson,Emmanuel Peprah,David M. Pereira,Norberto Perico,Konrad Pesudovs,Max Petzold,Michael R. Phillips,Michael R. Phillips,Julian David Pillay,Dietrich Plass,Suzanne Polinder,Farshad Pourmalek,David M. Prokop,Mostafa Qorbani,Anwar Rafay,Kazem Rahimi,Vafa Rahimi-Movaghar,Mahfuzar Rahman,Mohammad Hifz Ur Rahman,Sajjad Ur Rahman,Rajesh Kumar Rai,Sasa Rajsic,Usha Ram,Saleem M Rana,P. V. Rao,Giuseppe Remuzzi,David Rojas-Rueda,Luca Ronfani,Gholamreza Roshandel,Gholamreza Roshandel,Ambuj Roy,George Mugambage Ruhago,Mohammad Yahya Saeedi,Rajesh Sagar,Muhammad Muhammad Saleh,Juan Sanabria,Itamar S. Santos,Rodrigo Sarmiento-Suarez,Benn Sartorius,Monika Sawhney,Aletta E. Schutte,David C. Schwebel,Soraya Seedat,Sadaf G. Sepanlou,Edson Serván-Mori,Masood Ali Shaikh,Rajesh Sharma,Jun She,Sara Sheikhbahaei,Jiabin Shen,Jiabin Shen,Kenji Shibuya,Hwashin Hyun Shin,Inga Dora Sigfusdottir,Naris Silpakit,Diego Augusto Santos Silva,Dayane Gabriele Alves Silveira,Edgar P. Simard,Shireen Sindi,Jasvinder A. Singh,Om P. Singh,Prashant Singh,Vegard Skirbekk,Karen Sliwa,Samir Soneji,Reed J D Sorensen,Joan B. Soriano,David O Soti,Chandrashekhar T Sreeramareddy,Vasiliki Stathopoulou,Nicholas Steel,Bruno F. Sunguya,Soumya Swaminathan,Bryan L. Sykes,Rafael Tabarés-Seisdedos,Roberto Tchio Talongwa,Mohammad Tavakkoli,Bineyam Taye,Bemnet Amare Tedla,Bemnet Amare Tedla,Tesfaye Tekle,Girma Temam Shifa,Girma Temam Shifa,Awoke Misganaw Temesgen,Abdullah Sulieman Terkawi,Abdullah Sulieman Terkawi,Fisaha Haile Tesfay,Fisaha Haile Tesfay,Gizachew Assefa Tessema,Gizachew Assefa Tessema,Kiran Thapa,Alan J Thomson,Andrew L. Thorne-Lyman,Ruoyan Tobe-Gai,Roman Topor-Madry,Jeffrey A. Towbin,Jeffrey A. Towbin,Bach Xuan Tran,Zacharie Tsala Dimbuene,Nikolaos Tsilimparis,Abera Kenay Tura,Kingsley N. Ukwaja,Chigozie Jesse Uneke,Olalekan A. Uthman,Narayanaswamy Venketasubramanian,Sergey K Vladimirov,Vasiliy Victorovich Vlassov,Stein Emil Vollset,Stein Emil Vollset,Linhong Wang,Elisabete Weiderpass,Robert G. Weintraub,Andrea Werdecker,Ronny Westerman,Tissa Wijeratne,James D. Wilkinson,James D. Wilkinson,Charles Shey Wiysonge,Charles D.A. Wolfe,Charles D.A. Wolfe,Sungho Won,Sungho Won,John Q. Wong,Gelin Xu,Ajit Kumar Yadav,Bereket Yakob,Ayalnesh Zemene Yalew,Yuichiro Yano,Mehdi Yaseri,Mehdi Yaseri,Henock Yebyo,Henock Yebyo,Paul S. F. Yip,Naohiro Yonemoto,Seok Jun Yoon,Mustafa Z. Younis,Chuanhua Yu,Shicheng Yu,Zoubida Zaidi,Maysaa El Sayed Zaki,Hajo Zeeb,Hao Zhang,Yong Zhao,Sanjay Zodpey,Leo Zoeckler,Liesl Zühlke,Alan D. Lopez,Christopher J L Murray +500 more
TL;DR: This report provides national estimates of levels and trends of HIV/AIDS incidence, prevalence, coverage of antiretroviral therapy (ART), and mortality for 195 countries and territories from 1980 to 2015.
Journal ArticleDOI
A prospective ascertainment of cancer incidence in sub-Saharan Africa: The case of Kaposi sarcoma.
Aggrey Semeere,Megan Wenger,Naftali Busakhala,Nathan Buziba,Mwebesa Bwana,Winnie Muyindike,Erin Amerson,Toby Maurer,Timothy H. McCalmont,Philip E. LeBoit,Beverly Musick,Constantin T. Yiannoutsos,Robert Lukande,Barbara Castelnuovo,Miriam Laker-Oketta,Miriam Laker-Oketta,Andrew Kambugu,David V. Glidden,Kara Wools-Kaloustian,Jeffrey N. Martin +19 more
TL;DR: Despite reductions over time coincident with the expansion of ART, KS incidence among HIV‐infected adults in East Africa equals or exceeds the most common cancers in resource‐replete settings.
Journal ArticleDOI
Accuracy of Clinical Suspicion and Pathologic Diagnosis of Kaposi Sarcoma in East Africa.
Erin Amerson,Carina M. Woodruff,Amy K. Forrestel,Megan Wenger,Timothy H. McCalmont,Philip E. LeBoit,Toby Maurer,Miriam Laker-Oketta,Winnie Muyindike,Mwebesa Bwana,Nathan Buziba,Naftali Busakhala,Kara Wools-Kaloustian,Jeffrey N. Martin +13 more
TL;DR: Suboptimal positive predictive value of clinical suspicion of KS and specific, but not sensitive, histopathologic interpretation are found among East African HIV-infected patients, calling for abandonment of isolated clinical diagnosis of KS in the region and augmentation of local dermatopathologic services.
Journal ArticleDOI
HIV/AIDS in South Africa: How Many People Died From the Disease Between 1997 and 2010?
Debbie Bradshaw,William Msemburi,Rob E. Dorrington,Victoria Pillay-van Wyk,Ria Laubscher,Pam Groenewald +5 more
TL;DR: Empirically based estimates confirm the considerable loss of life from HIV/AIDS and should be used for calibrating models of the AIDS epidemic which generally appear too low for infants but too high for other ages.
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