Exosomes as biomarker treasure chests for prostate cancer.
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852 citations
Cites background from "Exosomes as biomarker treasure ches..."
...Multiple independent studies have reported that exosomes contain miRNA, and exosomes have been proposed to be treasure chests for biomarker applications (22, 26)....
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792 citations
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542 citations
Cites background from "Exosomes as biomarker treasure ches..."
...The utility of extracellular vesicles as disease biomarkers has attracted considerable interest in recent years (1)....
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425 citations
References
10,484 citations
"Exosomes as biomarker treasure ches..." refers background in this paper
...In terms of RNAs, the first study on exosomes was performed in 2007 [28]....
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...By transferring RNAs, exosomes are capable of transferring genetic information that can be translated into functional proteins in target cells [28]....
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4,492 citations
"Exosomes as biomarker treasure ches..." refers background in this paper
...Exosomes 50–150 CD9, CD63, CD81, CD82, annexins, and RAB proteins PCA3, TMPRSS2:ERG Merocrine Antigen presentation, immune regulatory, and metastatic activity [10,45,67,68]...
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4,380 citations
"Exosomes as biomarker treasure ches..." refers background in this paper
...Their discovery in sheep reticulocyte maturation gave rise to the idea that exosomes may function as a trash bin for unnecessary and redundant proteins and therefore could be an alternative pathway for lysosomal degradation [22]....
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4,118 citations
4,062 citations
"Exosomes as biomarker treasure ches..." refers background in this paper
...The detection sensitivity can increase approximately 100fold by combining these two methods; however, it is still not enough to identify the low-abundance markers [8]....
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