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Experimental radiation-induced heart disease. I. Light microscopic studies.

Luis F. Fajardo, +1 more
- 01 May 1970 - 
- Vol. 59, Iss: 2, pp 299-316
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This article is published in American Journal of Pathology.The article was published on 1970-05-01 and is currently open access. It has received 151 citations till now.

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Tolerance of normal tissue to therapeutic irradiation.

TL;DR: The updated information on tolerance of normal tissues of concern in the protocols of this contract, based on available data, is presented, with a special emphasis on partial volume effects.
Journal ArticleDOI

ICRP PUBLICATION 118: ICRP Statement on Tissue Reactions and Early and Late Effects of Radiation in Normal Tissues and Organs – Threshold Doses for Tissue Reactions in a Radiation Protection Context

TL;DR: Estimates of ‘practical’ threshold doses for tissue injury defined at the level of 1% incidence are provided and it appears that the rate of dose delivery does not modify the low incidence for reactions manifesting very late after low total doses, particularly for cataracts and circulatory disease.

ICRP statement on tissue reactions and early and late effects of radiation in normal tissues and organs -- threshold doses for tissue reactions in a radiation protection context

TL;DR: In this paper, the authors present a statement on the early and late effects of ionising radiation in normal tumor and kidney responses to irradiation, as well as some modifications of normal tumor response.
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The war on cancer

TL;DR: It is 25 years since then President Nixon "declared" War on Cancer and substantial advances in molecular oncology have yet to impinge on mortality statistics.
Journal ArticleDOI

Pathological Mechanisms of Fatal Late Coronary Stent Thrombosis in Humans

TL;DR: Stenting across branch ostia, disruption of adjacent vulnerable plaques, radiation therapy, and extensive plaque prolapse can precipitate late stent thrombosis, a potentially fatal complication of coronary stenting.
References
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Dose, time and fractionation: A clinical hypothesis

TL;DR: A formula is suggested which relates total dose, number of fractions and overall treatment time to a quantity termed ‘Nominal Standard Dose’, which represents the biological effect of a given treatment regime.
Journal ArticleDOI

The synergism of x-irradiation and cholesterol-fat feeding on the development of coronary artery lesions.

TL;DR: High cholesterol diet produced xanthomatoses limited to the origins of the major coronary arteries and intramyocardial branches of rabbits, and deposition of lipid in portions of vessels damaged by X-irradiation was probably one of the prime mechanisms in the genesis of these lesions.
Journal ArticleDOI

Effects of Radiations on the Heart

TL;DR: A clinical and electrocardiographic study of the effects of radiations on the heart is prefaced by a critical review of the clinical and experimental literature.
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