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Exploring the Role of Heavy Metals and Their Derivatives on the Pathophysiology of COVID-19.

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TLDR
In this paper, the effects of heavy metals and heavy metal nanoparticles on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its disease, COVID-19, have been studied to determine its properties, transmission mechanisms, and pathology.
Abstract
Many aspects of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its disease, COVID-19, have been studied to determine its properties, transmission mechanisms, and pathology. These efforts are aimed at identifying potential approaches to control or treat the disease. Early treatment of novel SARS-CoV-2 infection to minimize symptom progression has minimal evidence; however, many researchers and firms are working on vaccines, and only a few vaccines exist. COVID-19 is affected by several heavy metals and their nanoparticles. We investigated the effects of heavy metals and heavy metal nanoparticles on SARS-CoV-2 and their roles in COVID-19 pathogenesis. AgNPs, AuNPs, gold-silver hybrid NPs, copper nanoparticles, zinc oxide, vanadium, gallium, bismuth, titanium, palladium, silver grafted graphene oxide, and some quantum dots were tested to see if they could minimize the severity or duration of symptoms in patients with SARS-CoV-2 infection when compared to standard therapy.

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Comparative Analysis of Serum Zinc, Copper and Magnesium Level and Their Relations in Association with Severity and Mortality in SARS-CoV-2 Patients

TL;DR: In this paper , the relationship of trace metals in association with severity and mortality in SARS-CoV-2 patients was studied, where a total of 150 individuals infected with COVID-19 and 50 healthy individuals were recruited, and cases were divided based on severity (mild, moderate and severe) and outcome (discharged or deceased).
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Beneficial Effects of Vitamins, Minerals, and Bioactive Peptides on Strengthening the Immune System Against COVID-19 and the Role of Cow’s Milk in the Supply of These Nutrients

TL;DR: In this article, the effects of cow's milk vitamins, minerals, and bioactive peptides on general health in humans to combat viral diseases, especially COVID-19, and to what extent cow milk consumption plays a role in providing these metabolites.
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Antibacterial and Antiviral Effects of Ag, Cu and Zn Metals, Respective Nanoparticles and Filter Materials Thereof against Coronavirus SARS-CoV-2 and Influenza A Virus

TL;DR: In this article , metal-based nanoparticles (NPs) were used for filtering cellulose acetate (CA) fibers to produce antiviral and antibacterial filter materials for face masks.
Journal ArticleDOI

Current Trends and Prospects for Application of Green Synthesized Metal Nanoparticles in Cancer and COVID-19 Therapies

TL;DR: In this paper , a review of metal nanoparticles and their potential application in cancer and COVID-19 treatments is presented, where the authors highlight the great potential of metal and metal oxide nanoparticles as alternative nanotherapeutics, issues of nanotoxicity, complex methods of preparation, biodegradability and clearance are lingering challenges for the successful clinical application of the NPs.
References
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Journal ArticleDOI

Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics

TL;DR: The new generations of qdots have far-reaching potential for the study of intracellular processes at the single-molecule level, high-resolution cellular imaging, long-term in vivo observation of cell trafficking, tumor targeting, and diagnostics.
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Nanocarriers as an emerging platform for cancer therapy

TL;DR: The arsenal of nanocarriers and molecules available for selective tumour targeting, and the challenges in cancer treatment are detailed and emphasized.
Journal ArticleDOI

Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China.

TL;DR: This study conducted a retrospective multicenter study of 68 death cases and 82 discharged cases with laboratory-confirmed infection of SARS-CoV-2 and confirmed that some patients died of fulminant myocarditis, which is characterized by a rapid progress and a severe state of illness.
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