Expression of M-N#1, a histo-blood group B–like antigen, is strongly up-regulated in nonapoptosing mammary epithelial cells during rat mammary gland involution
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20 citations
Cites background from "Expression of M-N#1, a histo-blood ..."
...Note that the lactating mammary gland sample is overloaded to permit a glyceraldehyde-3-phosphate dehydrogenase (GAPDH) signal to be seen because we have previously shown that GAPDH expression is up-regulated during mammary gland involution (Mengwasser and Sleeman, 2001)....
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...The essentially blood group B antigen M-N1 is strongly up-regulated in involuting mammary glands (Mengwasser and Sleeman, 2001)....
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...Additionally, dexamethasone treatment inhibits tissue remodeling but not apoptosis in involuting mammary glands (Lund et al., 1996; Li et al., 1997; Mengwasser and Sleeman, 2001; data presented herein) and also suppresses galectin-3 expression (Figure 3, Figure 5, Table II)....
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...We have previously demonstrated that the M-N1 antigen is not expressed on apoptosing cells in this context (Mengwasser and Sleeman, 2001)....
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...Glucocorticoid hormones have been reported to be able to inhibit the second stage of involution in postlactating animals (Lund et al., 1996; Li et al., 1997; Mengwasser and Sleeman, 2001)....
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3 citations
Cites background from "Expression of M-N#1, a histo-blood ..."
...It was shown that a histo-blood group B-like antigen is strongly upregulated during rat mammary gland involution, implying that this antigen might either provide a survival function and/ or be expressed in epithelial cells destined to remodel mammary ducts (Mengwasser and Sleeman 2001)....
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References
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"Expression of M-N#1, a histo-blood ..." refers background in this paper
...Only humans and certain primates carry ABH antigens on endothelial cells and on erythrocytes (Oriol et al., 1994)....
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