Journal ArticleDOI
Extensive intestinal spirochaetosis in pigs challenged with Brachyspira pilosicoli.
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TLDR
This study is the first to report extensive intestinal spirochaetosis in pigs challenged with B. pilosicoli, and revealed extensively on the mucosal surface of the large intestines by light microscopy and fluorescent in situ hybridization.Abstract:
A field isolate of Brachyspira pilosicoli, the aetiological agent of porcine intestinal spirochaetosis, was inoculated by stomach tube into six 6-week-old pigs. All animals developed loose to watery faeces and were killed successively on days 8, 14 or 17 post-inoculation (day 17 being the end of the study). Mild mucosal reddening and flecks of pus characterized the gross lesions, while diffuse, catarrhal colitis was revealed microscopically in all animals. Intestinal spirochaetosis with moderate to densely packed end-attached B. pilosicoli organisms was revealed extensively on the mucosal surface of the large intestines by light microscopy and fluorescent in situ hybridization. This study is the first to report extensive intestinal spirochaetosis in pigs challenged with B. pilosicoli.read more
Citations
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Journal ArticleDOI
The Histological Features of Intestinal Spirochetosis in a Series of 113 Patients
TL;DR: It is concluded that spirochetosis in an unselected general population is unlikely to be of pathological significance and if spirochetes are observed in an inflamed biopsy, it is most likely to be an incidental finding.
Journal ArticleDOI
The Spirochete Brachyspira pilosicoli, Enteric Pathogen of Animals and Humans.
TL;DR: Clinicians and clinical microbiologists are encouraged to consider B. pilosicoli in their differential diagnoses and to develop and use appropriate diagnostic protocols to identify the spirochete in clinical specimens.
Journal ArticleDOI
First isolation of “Brachyspira hampsonii” from pigs in Europe
Maxime Mahu,E. de Jong,N. De Pauw,L. Vande Maele,Virginie Vandenbroucke,Tamara Vandersmissen,C. Miry,Frank Pasmans,Freddy Haesebrouck,An Martel,Filip Boyen +10 more
TL;DR: Three more weakly haemolytic Brachyspira species are designated, namely Brachypira intermedia , Brachys Pira murdochii and BrachysPira pilosicoli, which diverge in the severity of clinical symptoms they cause.
Journal ArticleDOI
Etiology of Colitis-Complex Diarrhea in Growing Pigs: A Review.
TL;DR: The exact etiology of CCD is still unclear; however, pathogens including Brachyspira (B.) hyodysenteriae, B. pilosicoli, and swine whipworms such as Trichuris (T.) suis have been involved in specific colitis (SC).
Journal ArticleDOI
Neither Hippurate-negative Brachyspira pilosicoli nor Brachyspira pilosicoli Type Strain Caused Diarrhoea in Early-weaned Pigs by Experimental Infection
M. Fossi,K. Ahlsten,Tarja Pohjanvirta,M. Anttila,T. Kokkonen,Tim Kåre Jensen,Mette Boye,Antti Sukura,K. Pelkola,Sinikka Pelkonen +9 more
TL;DR: The failure of B. pilosicoli strains to cause diarrhoea is discussed with respect to infectivity of the challenge strains, absence of certain intestinal pathogens and feed and management factors.
References
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Journal ArticleDOI
Serpulina pilosicoli sp. nov., the Agent of Porcine Intestinal Spirochetosis
Darren J. Trott,Thaddeus B. Stanton,Neil S. Jensen,Gerald E. Duhamel,John L. Johnson,David J. Hampson +5 more
TL;DR: DNA-DNA relative reassociation experiments in which the S1 nuclease method was used revealed that intestinal spirochete strain P43/6/78T was related to, but was genetically distinct from, both S. hyodysenteriae B78T and S. innocens B256T, and it is proposed that strain P 43/ 6/78 should be designated as the type strain of a new species, Serpulina pilosicoli.
Journal ArticleDOI
Production of diarrhoea and dysentery in pigs by feeding pure cultures of a spirochaete differing from Treponema hyodysenteriae.
DJ Taylor,JR Simmons,HM Laird +2 more
TL;DR: A weakly beta-haemolytic spirochaete, isolate P43/6/78, was isolated from a pig with diarrhoea and found not to fluoresce with a specific fluorescent antiserum to Treponema hyodysenteriae, and was considered to belong to a species other than T hyodysteriae.
Journal ArticleDOI
Detection of Lawsonia intracellularis, Serpulina hyodysenteriae, weakly beta-haemolytic intestinal spirochaetes, Salmonella enterica, and haemolytic Escherichia coli from swine herds with and without diarrhoea among growing pigs
TL;DR: Herd-type had a significant impact, that is specific pathogen-free herds showed an odds ratio at 0.2 relative to conventional herds for the development of diarrhoea.
Journal ArticleDOI
Experimental infection of newly weaned pigs with human and porcine strains of Serpulina pilosicoli.
TL;DR: The role of S. pilosicoli in the etiology of PIS is confirmed and evidence that S. Pilosicol strains of human origin have pathogenic potential in an animal model is provided.
Journal ArticleDOI
Investigations into field cases of porcine colitis with particular reference to infection with Serpulina pilosicoli
TL;DR: Despite the successful treatment of batches of pig units with tiamulin or lincomycin, S pilosicoli infection persisted as a chronic problem on many units, with diarrhoea and colitis in successive batches of pigs unless prophylactic medication was used.
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