Extent of recovery from the effects of visual deprivation in kittens.
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Cites background from "Extent of recovery from the effects..."
...…the visually excitable cells are still orientation selective at 6 weeks (and even beyond 24 months of age) and the proportion of binocular cells is less than normal (Wiesel and Hubel, 1965; Blakemore and Van Sluyters, 1975; Kratz and Spear, 1976; Leventhal and Hirsch, 1977; Watkins et al., 1978 )....
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...…during a " critical " period (ranging from about 3 to about 12 weeks), results in a rapid loss of binocularity, to the profit of the open eye (Wiesel and Hubel, 1963, 1965); then, opening the closed eye and closing the experienced one may result in a complete reversal of ocular dominance…...
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...Of all visual deprivation paradigms, putting one eye in a competitive advantage over the other has probably the most striking consequences: monocular lid suture (MD), if it is performed during a “critical” period (ranging from about 3 to about 12 weeks), results in a rapid loss of binocularity, to the profit of the open eye ( Wiesel and Hubel, 1963, 1965 ); then, opening the closed eye and closing the experienced one may result in a complete ......
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...In animals whose eyelids have been sutured at birth and which are thus binocularly deprived of pattern vision (BD), a somewhat higher proportion (from 12 to 50%) of the visually excitable cells are still orientation selective at 6 weeks (and even beyond 24 months of age) and the proportion of binocular cells is less than normal ( Wiesel and Hubel, 1965; Blakemore and Van Sluyters, 1975; Kratz and Spear, 1976; Leventhal and Hirsch, 1977; ......
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2,281 citations
Cites background from "Extent of recovery from the effects..."
...Hubel and Wiesel established a programme to examine the effects of selective visual deprivation during development on the anatomy and physiology of the visual corte...
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References
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"Extent of recovery from the effects..." refers background or result in this paper
...Taken together, these two results reinforce our conclusions from the binocular closures and strabismus experiments (8, 3) in suggesting a strong interdependence in the pathways originating from the two eyes....
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...The change resembles that seen in animals raised with squint or with alternating contact occluders (3), both conditions in which the synergic action of the two eyes is eliminated without the complication of complete disuse....
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1,238 citations
"Extent of recovery from the effects..." refers background or methods in this paper
...(As discussed previously (6), cell sizes vary to some extent from one animal to the next, partly, no doubt, because of differences in fixation....
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...Several kittens were therefore raised with the lids of one or both eyes sutured t !ogether for 3 months, as in previous experiments (6), and then the closed eye was reo pened and the animals were allowed to live for another 3-14 months before making observations....
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...These include behavioral blindness, morphological changes in the lateral geniculate body, and disruption of innately determined cortical connections (2, 6-8)....
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...Anatomica and physiological methods are described in other papers (1, 6, 8)....
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